DE69802789D1 - Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-carnitin-oder alkanoyl-l-carnitin mit 2-aminosulfonsäure enthalten - Google Patents

Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-carnitin-oder alkanoyl-l-carnitin mit 2-aminosulfonsäure enthalten

Info

Publication number
DE69802789D1
DE69802789D1 DE69802789T DE69802789T DE69802789D1 DE 69802789 D1 DE69802789 D1 DE 69802789D1 DE 69802789 T DE69802789 T DE 69802789T DE 69802789 T DE69802789 T DE 69802789T DE 69802789 D1 DE69802789 D1 DE 69802789D1
Authority
DE
Germany
Prior art keywords
carnitine
solid compositions
pct
alkanoyl
carnitin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69802789T
Other languages
English (en)
Other versions
DE69802789T2 (de
Inventor
Nazareno Scafetta
Ornella Tinti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE69802789D1 publication Critical patent/DE69802789D1/de
Application granted granted Critical
Publication of DE69802789T2 publication Critical patent/DE69802789T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Husbandry (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
DE69802789T 1997-04-01 1998-03-19 Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-carnitin-oder alkanoyl-l-carnitin mit 2-aminosulfonsäure enthalten Expired - Lifetime DE69802789T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97RM000184A IT1291126B1 (it) 1997-04-01 1997-04-01 Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
PCT/IT1998/000060 WO1998043945A1 (en) 1997-04-01 1998-03-19 Solid compositions suitable for oral administration comprising non hygroscopic salts of l-carnitine and alkanoyl-l-carnitine with 2-aminoethanesulfonic acid

Publications (2)

Publication Number Publication Date
DE69802789D1 true DE69802789D1 (de) 2002-01-17
DE69802789T2 DE69802789T2 (de) 2002-07-18

Family

ID=11404924

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802789T Expired - Lifetime DE69802789T2 (de) 1997-04-01 1998-03-19 Feste zusammensetzungen für orale verabreichung die nicht-hygroskopische salze von l-carnitin-oder alkanoyl-l-carnitin mit 2-aminosulfonsäure enthalten

Country Status (23)

Country Link
US (1) US6124360A (de)
EP (1) EP0971880B1 (de)
JP (1) JP4047935B2 (de)
KR (1) KR100562055B1 (de)
CN (1) CN1187318C (de)
AT (1) ATE210111T1 (de)
AU (1) AU733272B2 (de)
BR (1) BR9808461A (de)
CA (1) CA2285380C (de)
CZ (1) CZ296465B6 (de)
DE (1) DE69802789T2 (de)
DK (1) DK0971880T3 (de)
ES (1) ES2167878T3 (de)
HK (1) HK1025560A1 (de)
HU (1) HU226109B1 (de)
IL (2) IL131956A0 (de)
IT (1) IT1291126B1 (de)
NZ (1) NZ500537A (de)
PL (1) PL189488B1 (de)
PT (1) PT971880E (de)
SI (1) SI0971880T1 (de)
SK (1) SK283392B6 (de)
WO (1) WO1998043945A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090849A (en) * 1999-03-23 2000-07-18 The Board Of Regents For Oklahoma State University Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry
IT1305308B1 (it) * 1999-03-26 2001-05-04 Biosint S P A Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione
IT1317924B1 (it) 2000-10-31 2003-07-15 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
DE20321010U1 (de) * 2003-03-28 2005-12-29 Schymura, Martin Fruchtgummizusammensetzung
CN104276986B (zh) * 2013-07-12 2016-07-06 辽宁科硕营养科技有限公司 左旋肉碱牛磺酸盐的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1153640A (en) * 1967-04-10 1969-05-29 Soc D Etudes Prod Chimique A Carnitin Salt
FR2529545B1 (fr) * 1982-07-02 1985-05-31 Sanofi Sa Nouveaux sels de carnitine ainsi que leur procede de preparation
EP0150688B1 (de) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salze von L-Carnitin und Alkanoyl-L-Carnitinen sowie Verfahren zur Herstellung derselben
IT1188176B (it) * 1985-07-05 1988-01-07 Bicresearch Spa Sali della carnitina particolarmente idonei per uso orale
SE8701662L (sv) * 1987-04-22 1988-10-23 Gelder Nico M Van Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
US5073376A (en) * 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine
US5571783A (en) * 1993-03-09 1996-11-05 Clintec Nutrition Company Composition and method for treating patients with hepatic disease
IT1261688B (it) * 1993-05-28 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
US5589468A (en) * 1995-01-13 1996-12-31 Clintec Nutrition Co. Method for providing nutrition to elderly patients

Also Published As

Publication number Publication date
CZ296465B6 (cs) 2006-03-15
US6124360A (en) 2000-09-26
SI0971880T1 (en) 2002-06-30
NZ500537A (en) 2001-03-30
DK0971880T3 (da) 2002-03-04
EP0971880A1 (de) 2000-01-19
BR9808461A (pt) 2000-05-23
EP0971880B1 (de) 2001-12-05
ES2167878T3 (es) 2002-05-16
HU226109B1 (en) 2008-04-28
ITRM970184A1 (it) 1998-10-01
IT1291126B1 (it) 1998-12-29
JP2001517227A (ja) 2001-10-02
CN1187318C (zh) 2005-02-02
PL189488B1 (pl) 2005-08-31
CA2285380A1 (en) 1998-10-08
SK135099A3 (en) 2000-05-16
SK283392B6 (sk) 2003-07-01
HUP0001866A2 (hu) 2000-11-28
HK1025560A1 (en) 2000-11-17
PL335937A1 (en) 2000-05-22
WO1998043945A1 (en) 1998-10-08
CN1251573A (zh) 2000-04-26
PT971880E (pt) 2002-05-31
AU6745598A (en) 1998-10-22
CA2285380C (en) 2008-07-08
HUP0001866A3 (en) 2002-09-30
AU733272B2 (en) 2001-05-10
CZ347899A3 (cs) 2000-04-12
KR100562055B1 (ko) 2006-03-17
IL131956A0 (en) 2001-03-19
ATE210111T1 (de) 2001-12-15
DE69802789T2 (de) 2002-07-18
KR20010005867A (ko) 2001-01-15
IL131956A (en) 2007-09-20
JP4047935B2 (ja) 2008-02-13

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Legal Events

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