HUP0001808A2 - Antitestek, amelyek a laminin nidogén-kötődoménjéhez kötődnek, előállításuk és alkalmazásuk - Google Patents
Antitestek, amelyek a laminin nidogén-kötődoménjéhez kötődnek, előállításuk és alkalmazásukInfo
- Publication number
- HUP0001808A2 HUP0001808A2 HU0001808A HUP0001808A HUP0001808A2 HU P0001808 A2 HUP0001808 A2 HU P0001808A2 HU 0001808 A HU0001808 A HU 0001808A HU P0001808 A HUP0001808 A HU P0001808A HU P0001808 A2 HUP0001808 A2 HU P0001808A2
- Authority
- HU
- Hungary
- Prior art keywords
- laminin
- antibodies
- bind
- nidogen
- binding domain
- Prior art date
Links
- 108010008217 nidogen Proteins 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011435 rock Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A találmány fajlagősan a laminin nidőgén-kötődőménjéhez kötődőmőnőklónális és pőliklónális antitestekre, részeikre, az antitestekelőállítására irányűló eljárásra, és gyógyszerkénti, laminin-izőfőrmákkiműtatására szőlgáló diagnősztikűmkénti, valamint a nidőgén/laminin-interakciók befőlyásőló anyagők kifejlesztése és értékelése sőránmődellanyagkénti alkalmazásűkra vőnatkőzik. A találmány szerintiantitestek vagy részeik, főleg a laminin g1 III 4-kötődőménjéhez, ezenbelül az a-hűrők illetve a- és c-hűrők erősen kőnzervált tartőmányábanlévő lényeges nidőgénkötőhelyekhez kötődnek, és a laminin és nidőgénösszekapcsőlódását gátőlhatják. ŕ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19701607A DE19701607A1 (de) | 1997-01-17 | 1997-01-17 | Anitkörper, die an die Nidogen-Bindungsdomäne des Laminins binden, deren Herstellung und Verwendung |
| PCT/EP1997/007241 WO1998031709A1 (de) | 1997-01-17 | 1997-12-22 | Antikörper, die an die nidogen-bindungsdomäne des laminins binden, deren herstellung und verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0001808A2 true HUP0001808A2 (hu) | 2000-09-28 |
| HUP0001808A3 HUP0001808A3 (en) | 2001-09-28 |
Family
ID=7817701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0001808A HUP0001808A3 (en) | 1997-01-17 | 1997-12-22 | Antibodies that bind to the nidogen-binding domain of laminin, their production and use |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20010007020A1 (hu) |
| EP (1) | EP0954535A1 (hu) |
| JP (1) | JP2001509020A (hu) |
| KR (1) | KR20000070256A (hu) |
| CN (1) | CN1244873A (hu) |
| AR (1) | AR011074A1 (hu) |
| AU (1) | AU5985398A (hu) |
| BR (1) | BR9714207A (hu) |
| CA (1) | CA2278477A1 (hu) |
| CZ (1) | CZ253899A3 (hu) |
| DE (1) | DE19701607A1 (hu) |
| HU (1) | HUP0001808A3 (hu) |
| ID (1) | ID21895A (hu) |
| IL (1) | IL130808A0 (hu) |
| PL (1) | PL334956A1 (hu) |
| TR (1) | TR199901648T2 (hu) |
| WO (1) | WO1998031709A1 (hu) |
| ZA (1) | ZA98367B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030087318A1 (en) * | 1994-04-18 | 2003-05-08 | Lallone Roger L. | Antibodies against an extracellular matrix complex and their use in the detection of cancer |
| EP1070727A1 (en) | 1999-03-01 | 2001-01-24 | Aventis Pharma Deutschland GmbH | Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction |
| CA2389751A1 (en) * | 1999-11-01 | 2001-05-10 | Curagen Corporation | Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same |
| AU2001237068A1 (en) * | 2000-02-18 | 2001-08-27 | Jagat Narula | Detection of microbial deposition and immune response at the basement membrane |
| WO2001073033A2 (en) * | 2000-03-29 | 2001-10-04 | Beth Israel Deaconess Medical Center, Inc. | Anti-angiogenic and anti-tumor properties of matin and other laminin domains |
| US20030119739A1 (en) * | 2000-03-29 | 2003-06-26 | Beth Israel Deaconess Medical Center | Anti-angiogenic and anti-tumor properties of Vascostatin and other nidogen domains |
| WO2004093892A2 (en) | 2003-04-16 | 2004-11-04 | Genentech, Inc. | Stanniocalcin-1, variant or antagonists thereof for selective modulation of vascularization |
| US20140045196A1 (en) * | 2012-08-13 | 2014-02-13 | University Of Tokyo | Methods of prognosis and diagnosis of cancer |
| CN110860766A (zh) * | 2019-10-22 | 2020-03-06 | 广东开放大学（广东理工职业学院） | 铝合金薄板的调制脉冲电流焊接方法、系统及存储介质 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211657A (en) * | 1988-11-07 | 1993-05-18 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides |
| EP1942116B1 (de) * | 1994-08-11 | 2014-01-22 | Sanofi-Aventis Deutschland GmbH | Monoklonale Antikörper zur selektiven immunologischen Bestimmung von hochmolekularen, intakten Lamininformen in Körperflüssigkeiten |
| US5493008A (en) * | 1994-08-15 | 1996-02-20 | The University Of Virginia Patent Foundation | Two non-contiguous regions contribute to nidogen binding to a single EGF-like motif of the laminin γ1 chain |
-
1997
- 1997-01-17 DE DE19701607A patent/DE19701607A1/de not_active Withdrawn
- 1997-12-22 EP EP97954750A patent/EP0954535A1/de not_active Withdrawn
- 1997-12-22 BR BR9714207-7A patent/BR9714207A/pt not_active IP Right Cessation
- 1997-12-22 US US09/341,643 patent/US20010007020A1/en not_active Abandoned
- 1997-12-22 PL PL97334956A patent/PL334956A1/xx unknown
- 1997-12-22 HU HU0001808A patent/HUP0001808A3/hu unknown
- 1997-12-22 CA CA002278477A patent/CA2278477A1/en not_active Abandoned
- 1997-12-22 JP JP53230298A patent/JP2001509020A/ja active Pending
- 1997-12-22 CN CN97181412A patent/CN1244873A/zh active Pending
- 1997-12-22 AU AU59853/98A patent/AU5985398A/en not_active Abandoned
- 1997-12-22 ID IDW990701A patent/ID21895A/id unknown
- 1997-12-22 TR TR1999/01648T patent/TR199901648T2/xx unknown
- 1997-12-22 KR KR1019997006484A patent/KR20000070256A/ko not_active Application Discontinuation
- 1997-12-22 IL IL13080897A patent/IL130808A0/xx unknown
- 1997-12-22 CZ CZ992538A patent/CZ253899A3/cs unknown
- 1997-12-22 WO PCT/EP1997/007241 patent/WO1998031709A1/de not_active Application Discontinuation
-
1998
- 1998-01-15 AR ARP980100177A patent/AR011074A1/es unknown
- 1998-01-16 ZA ZA98367A patent/ZA98367B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0001808A3 (en) | 2001-09-28 |
| CN1244873A (zh) | 2000-02-16 |
| AR011074A1 (es) | 2000-08-02 |
| ZA98367B (en) | 1998-07-17 |
| CA2278477A1 (en) | 1998-07-23 |
| AU5985398A (en) | 1998-08-07 |
| US20010007020A1 (en) | 2001-07-05 |
| IL130808A0 (en) | 2001-01-28 |
| EP0954535A1 (de) | 1999-11-10 |
| KR20000070256A (ko) | 2000-11-25 |
| DE19701607A1 (de) | 1998-07-23 |
| ID21895A (id) | 1999-08-05 |
| JP2001509020A (ja) | 2001-07-10 |
| WO1998031709A1 (de) | 1998-07-23 |
| TR199901648T2 (xx) | 1999-10-21 |
| PL334956A1 (en) | 2000-03-27 |
| CZ253899A3 (cs) | 1999-10-13 |
| BR9714207A (pt) | 2000-03-28 |
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