HUE065201T2 - Heterociklusos szubsztituált piridinszármazék gombaellenes szerek - Google Patents
Heterociklusos szubsztituált piridinszármazék gombaellenes szerekInfo
- Publication number
- HUE065201T2 HUE065201T2 HUE18885399A HUE18885399A HUE065201T2 HU E065201 T2 HUE065201 T2 HU E065201T2 HU E18885399 A HUE18885399 A HU E18885399A HU E18885399 A HUE18885399 A HU E18885399A HU E065201 T2 HUE065201 T2 HU E065201T2
- Authority
- HU
- Hungary
- Prior art keywords
- antifungal agents
- pyridine derivative
- substituted pyridine
- heterocycle substituted
- derivative antifungal
- Prior art date
Links
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003429 antifungal agent Substances 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762595894P | 2017-12-07 | 2017-12-07 | |
| US201862649225P | 2018-03-28 | 2018-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE065201T2 true HUE065201T2 (hu) | 2024-05-28 |
Family
ID=66751743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18885399A HUE065201T2 (hu) | 2017-12-07 | 2018-12-07 | Heterociklusos szubsztituált piridinszármazék gombaellenes szerek |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11512079B2 (hu) |
| EP (1) | EP3720438B1 (hu) |
| JP (2) | JP7292299B2 (hu) |
| KR (1) | KR20200096941A (hu) |
| CN (1) | CN111698989B (hu) |
| AU (1) | AU2018379077B2 (hu) |
| BR (1) | BR112020011162A2 (hu) |
| CA (1) | CA3084298A1 (hu) |
| DK (1) | DK3720438T3 (hu) |
| ES (1) | ES2962986T3 (hu) |
| FI (1) | FI3720438T3 (hu) |
| HU (1) | HUE065201T2 (hu) |
| IL (1) | IL275121A (hu) |
| MA (1) | MA51052A (hu) |
| MX (1) | MX2020005927A (hu) |
| PL (1) | PL3720438T3 (hu) |
| PT (1) | PT3720438T (hu) |
| WO (1) | WO2019113542A1 (hu) |
| ZA (1) | ZA202003281B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019113542A1 (en) | 2017-12-07 | 2019-06-13 | Amplyx Pharmaceuticals, Inc. | Heterocycle substituted pyridine derivative antifungal agents |
| CA3104653A1 (en) | 2018-06-25 | 2020-01-02 | Amplyx Pharmaceuticals, Inc. | Pyridine derivatives substituted by heterocyclic ring and amino group |
| WO2020247804A1 (en) * | 2019-06-07 | 2020-12-10 | Amplyx Pharmaceuticals, Inc. | Heterocycle substituted pyridine derivative antifungal agents |
| WO2021178406A1 (en) * | 2020-03-04 | 2021-09-10 | Amplyx Pharmaceuticals, Inc. | Use of compounds in the treatment of fungal infections |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| AU2002253432B2 (en) | 2001-04-05 | 2005-03-24 | Torrent Pharmaceuticals Ltd. | Heterocyclic compounds for aging-related and diabetic vascular complications |
| JO2785B1 (en) * | 2003-05-27 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinazoline derivatives |
| AU2006309762B2 (en) * | 2005-10-31 | 2010-02-25 | Eisai R&D Management Co., Ltd. | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| JP5525812B2 (ja) * | 2006-04-19 | 2014-06-18 | メルク セローノ ソシエテ アノニム | Ｍｅｋインヒビターとしての新規ヘテロアリール置換アリールアミノピリジン誘導体 |
| DE102006020327A1 (de) * | 2006-04-27 | 2007-12-27 | Bayer Healthcare Ag | Heterocyclisch substituierte, anellierte Pyrazol-Derivate und ihre Verwendung |
| KR20100015897A (ko) | 2007-04-27 | 2010-02-12 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 헤테로환 치환 피리딘 유도체의 염 또는 그의 결정 |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| US20100284993A1 (en) * | 2007-10-24 | 2010-11-11 | Mutz Mitchell W | Enhancing the Efficacy of Anti-Infective Therapeutics |
| RU2474581C2 (ru) | 2007-12-26 | 2013-02-10 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Способ получения замещенных гетероциклом производных пиридина |
| US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
| WO2010032874A1 (ja) * | 2008-09-19 | 2010-03-25 | 住友化学株式会社 | 農業用組成物 |
| US8188119B2 (en) | 2008-10-24 | 2012-05-29 | Eisai R&D Management Co., Ltd | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same |
| JP2012176900A (ja) | 2009-06-24 | 2012-09-13 | Eisai R & D Management Co Ltd | （（ホスホノオキシ）メチル）ピリジニウム環を有するピリジン誘導体およびそれらを含有する抗真菌剤 |
| WO2011051198A2 (de) * | 2009-10-30 | 2011-05-05 | Bayer Cropscience Ag | Pyridin-derivate als pflanzenschutzmittel |
| WO2019113542A1 (en) | 2017-12-07 | 2019-06-13 | Amplyx Pharmaceuticals, Inc. | Heterocycle substituted pyridine derivative antifungal agents |
| CA3104653A1 (en) | 2018-06-25 | 2020-01-02 | Amplyx Pharmaceuticals, Inc. | Pyridine derivatives substituted by heterocyclic ring and amino group |
| WO2020247804A1 (en) | 2019-06-07 | 2020-12-10 | Amplyx Pharmaceuticals, Inc. | Heterocycle substituted pyridine derivative antifungal agents |
-
2018
- 2018-12-07 WO PCT/US2018/064609 patent/WO2019113542A1/en active Search and Examination
- 2018-12-07 JP JP2020550050A patent/JP7292299B2/ja active Active
- 2018-12-07 AU AU2018379077A patent/AU2018379077B2/en active Active
- 2018-12-07 EP EP18885399.8A patent/EP3720438B1/en active Active
- 2018-12-07 CA CA3084298A patent/CA3084298A1/en active Pending
- 2018-12-07 CN CN201880088941.1A patent/CN111698989B/zh active Active
- 2018-12-07 KR KR1020207019209A patent/KR20200096941A/ko not_active Application Discontinuation
- 2018-12-07 FI FIEP18885399.8T patent/FI3720438T3/fi active
- 2018-12-07 PL PL18885399.8T patent/PL3720438T3/pl unknown
- 2018-12-07 PT PT188853998T patent/PT3720438T/pt unknown
- 2018-12-07 MA MA051052A patent/MA51052A/fr unknown
- 2018-12-07 MX MX2020005927A patent/MX2020005927A/es unknown
- 2018-12-07 BR BR112020011162-7A patent/BR112020011162A2/pt unknown
- 2018-12-07 US US16/770,476 patent/US11512079B2/en active Active
- 2018-12-07 DK DK18885399.8T patent/DK3720438T3/da active
- 2018-12-07 ES ES18885399T patent/ES2962986T3/es active Active
- 2018-12-07 HU HUE18885399A patent/HUE065201T2/hu unknown
-
2020
- 2020-06-02 ZA ZA2020/03281A patent/ZA202003281B/en unknown
- 2020-06-04 IL IL275121A patent/IL275121A/en unknown
-
2022
- 2022-09-23 US US17/934,629 patent/US20230065881A1/en active Pending
-
2023
- 2023-06-06 JP JP2023092871A patent/JP2023113800A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2962986T3 (es) | 2024-03-22 |
| CA3084298A1 (en) | 2019-06-13 |
| IL275121A (en) | 2020-07-30 |
| PT3720438T (pt) | 2023-12-07 |
| EP3720438A1 (en) | 2020-10-14 |
| EP3720438A4 (en) | 2021-06-16 |
| EP3720438B1 (en) | 2023-08-30 |
| MA51052A (fr) | 2021-04-21 |
| CN111698989A (zh) | 2020-09-22 |
| WO2019113542A1 (en) | 2019-06-13 |
| BR112020011162A2 (pt) | 2020-11-17 |
| US11512079B2 (en) | 2022-11-29 |
| US20230065881A1 (en) | 2023-03-02 |
| JP7292299B2 (ja) | 2023-06-16 |
| KR20200096941A (ko) | 2020-08-14 |
| FI3720438T3 (fi) | 2023-09-01 |
| PL3720438T3 (pl) | 2024-03-18 |
| US20210163461A1 (en) | 2021-06-03 |
| AU2018379077A1 (en) | 2020-06-25 |
| MX2020005927A (es) | 2020-10-07 |
| ZA202003281B (en) | 2023-10-25 |
| AU2018379077B2 (en) | 2023-04-27 |
| JP2023113800A (ja) | 2023-08-16 |
| CN111698989B (zh) | 2023-08-01 |
| DK3720438T3 (da) | 2023-10-02 |
| JP2021505672A (ja) | 2021-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL280573A (en) | 2-(het)aryl-converted compressed heterocycles as pest control agents | |
| ZA201807249B (en) | Heterocyclic compound | |
| ZA201803475B (en) | Condensed bicyclic heterocycle derivatives as pest control agents | |
| ZA201902232B (en) | Pyridine compound | |
| IL267850A (en) | Heterocyclic derivatives as pest control agents | |
| IL260908B (en) | Substituted 2-(het)aryl-imidazolyl-carboxyamides as pest control agents | |
| IL275121A (en) | Heterocycle-modified pyridine derivatives antifungal agents | |
| ZA201901596B (en) | Condensed bicyclic heterocycle derivatives as pest control agents | |
| IL267844A (en) | Heterocyclic derivatives as pest control agents | |
| IL260148A (en) | Heterocyclene derivatives as pest control agents | |
| IL260829B (en) | Substituted imidazolyl-carboxamides as pest control agents | |
| ZA201901024B (en) | Condensed bicyclic heterocycle derivatives as pest control agents | |
| IL272482A (en) | A pyridine compound is transformed with an azole | |
| PT3643718T (pt) | Composto heterocíclico e seu uso como modulador alostérico positivo do recetor muscarínico colinérgico m1 | |
| IL260640B (en) | Substituted 2-oxyimidazolyl-carboxamides as pest control agents | |
| HK1256022A1 (zh) | 唑類取代的吡啶化合物 | |
| EP3660003C0 (en) | HETEROCYCLIC COMPOUND | |
| ZA201701093B (en) | Aryl-triazolyl pyridines as pest control agents | |
| EP3693360C0 (en) | HETEROCYCLIC COMPOUNDS | |
| EP3693368C0 (en) | HETEROCYCLIC COMPOUND | |
| IL265578A (en) | 5-substituted imidazolylmethyldioxolane derivatives as fungicides | |
| ZA201807933B (en) | Substituted 2-alkylimidazolyl-carboxamides as pest control agents | |
| IL265638A (en) | 5-substituted imidazolylmethyloxirane derivatives as fungicides | |
| ZA201907793B (en) | Heterocyclic compound | |
| ZA201907792B (en) | Heterocyclic compound |