HUE059560T2 - Elõrehaladott rákban szenvedõ alanyok részére való aktivált dendritikus sejtkészítményekkel kapcsolatos eljárások - Google Patents
Elõrehaladott rákban szenvedõ alanyok részére való aktivált dendritikus sejtkészítményekkel kapcsolatos eljárásokInfo
- Publication number
- HUE059560T2 HUE059560T2 HUE16847253A HUE16847253A HUE059560T2 HU E059560 T2 HUE059560 T2 HU E059560T2 HU E16847253 A HUE16847253 A HU E16847253A HU E16847253 A HUE16847253 A HU E16847253A HU E059560 T2 HUE059560 T2 HU E059560T2
- Authority
- HU
- Hungary
- Prior art keywords
- subjects
- procedures
- dendritic cell
- cell preparations
- advanced cancer
- Prior art date
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A—HUMAN NECESSITIES
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
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- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/35—Cytokines
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- A—HUMAN NECESSITIES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5421—IL-8
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G01N33/56972—White blood cells
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
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- Urology & Nephrology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Food Science & Technology (AREA)
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- Epidemiology (AREA)
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- Wood Science & Technology (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562219058P | 2015-09-15 | 2015-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE059560T2 true HUE059560T2 (hu) | 2022-11-28 |
Family
ID=58289879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16847253A HUE059560T2 (hu) | 2015-09-15 | 2016-09-14 | Elõrehaladott rákban szenvedõ alanyok részére való aktivált dendritikus sejtkészítményekkel kapcsolatos eljárások |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20190046568A1 (enExample) |
| EP (2) | EP3350318B1 (enExample) |
| JP (3) | JP6980650B2 (enExample) |
| KR (1) | KR20180044430A (enExample) |
| CN (2) | CN108291204A (enExample) |
| AU (2) | AU2016323066B2 (enExample) |
| BR (1) | BR112018005180B1 (enExample) |
| CA (1) | CA2998614A1 (enExample) |
| DK (1) | DK3350318T3 (enExample) |
| ES (1) | ES2923769T3 (enExample) |
| HU (1) | HUE059560T2 (enExample) |
| IL (3) | IL286225B2 (enExample) |
| MX (2) | MX393996B (enExample) |
| PL (1) | PL3350318T3 (enExample) |
| RU (1) | RU2749610C2 (enExample) |
| WO (1) | WO2017048875A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190076473A1 (en) * | 2017-09-14 | 2019-03-14 | Cellular Approaches, Inc. | Autologous and allogenic macrophages and monocytes for use in therapeutic methods |
| CN110106145B (zh) * | 2019-06-12 | 2021-02-12 | 蓝莲(杭州)生物科技有限公司 | 一种未成熟树突状细胞培养液及其未成熟树突状细胞的制备方法 |
| WO2021071977A1 (en) * | 2019-10-07 | 2021-04-15 | Northwest Biotherapeutics, Inc. | In vitro methods and compositions for enhancing the activation of dendritic cells and t cells, and for inducing a th-1 immune response |
| CN119286782B (zh) * | 2024-12-11 | 2025-04-04 | 上海赛笠百傲生物医药有限公司 | 一种高效诱导外周血来源单核细胞至不成熟树突状细胞的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69333433T2 (de) | 1992-04-01 | 2004-12-02 | The Rockefeller University | Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung |
| US7659119B2 (en) | 1996-02-12 | 2010-02-09 | Argos Therapeutics, Inc. | Method and compositions for obtaining mature dendritic cells |
| US6558951B1 (en) * | 1999-02-11 | 2003-05-06 | 3M Innovative Properties Company | Maturation of dendritic cells with immune response modifying compounds |
| US20020094545A1 (en) | 2000-11-30 | 2002-07-18 | Harris Paul E. | Growth of human dendritic cells for cancer immunotherapy in closed system using microcarrier beads |
| AU2002326463A1 (en) | 2001-07-25 | 2003-02-17 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
| ES2755552T3 (es) | 2002-06-19 | 2020-04-22 | Northwest Biotherapeutics Inc | Dispositivos de filtración de flujo tangencial y métodos para el enriquecimiento de leucocitos |
| WO2004039968A1 (ja) * | 2002-10-30 | 2004-05-13 | Japan Science And Technology Agency | 骨髄由来の不死化樹状細胞株 |
| BRPI0317064B8 (pt) | 2002-12-06 | 2021-05-25 | Northwest Biotherapeutics Inc | composições compreendendo células dendríticas parcialmente amadurecidas in vitro |
| AU2004214896A1 (en) | 2003-02-27 | 2004-09-10 | Northwest Biotherapeutics, Inc. | Generation of dendritic cells from monocytic dendritic precursor cells with GM-CSF in the absence of additional cytokines |
| US20060257359A1 (en) * | 2005-02-28 | 2006-11-16 | Cedric Francois | Modifying macrophage phenotype for treatment of disease |
| KR20220113543A (ko) * | 2005-12-08 | 2022-08-12 | 노쓰웨스트 바이오써라퓨틱스, 인크. | 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 |
| EP2199793A4 (en) * | 2007-09-10 | 2012-01-11 | Riken | METHOD FOR EVALUATING HUMAN DENDRITIC CELLS AND HUMAN-CELL IMMUNOTHERAPEUTICS |
| EP2072617A1 (en) * | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
| EP2429585B1 (en) * | 2009-05-15 | 2018-04-18 | IRX Therapeutics, Inc. | Vaccine immunotherapy |
| CN103638517A (zh) * | 2013-12-04 | 2014-03-19 | 深圳市合一康生物科技有限公司 | 人树突状细胞疫苗制备的专用试剂盒 |
| WO2016048872A1 (en) * | 2014-09-23 | 2016-03-31 | Neostem Oncology, Llc | Compositions, methods and kits used to determine potency of dendritic cells in cancer immunitherpay |
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2016
- 2016-09-14 CN CN201680066721.XA patent/CN108291204A/zh active Pending
- 2016-09-14 IL IL286225A patent/IL286225B2/en unknown
- 2016-09-14 HU HUE16847253A patent/HUE059560T2/hu unknown
- 2016-09-14 CN CN202211533672.XA patent/CN116413420A/zh active Pending
- 2016-09-14 KR KR1020187010610A patent/KR20180044430A/ko active Pending
- 2016-09-14 WO PCT/US2016/051781 patent/WO2017048875A1/en not_active Ceased
- 2016-09-14 AU AU2016323066A patent/AU2016323066B2/en active Active
- 2016-09-14 EP EP16847253.8A patent/EP3350318B1/en active Active
- 2016-09-14 US US15/759,699 patent/US20190046568A1/en active Pending
- 2016-09-14 JP JP2018513634A patent/JP6980650B2/ja active Active
- 2016-09-14 PL PL16847253.8T patent/PL3350318T3/pl unknown
- 2016-09-14 MX MX2018003197A patent/MX393996B/es unknown
- 2016-09-14 EP EP21189488.6A patent/EP3971285A3/en active Pending
- 2016-09-14 CA CA2998614A patent/CA2998614A1/en active Pending
- 2016-09-14 DK DK16847253.8T patent/DK3350318T3/da active
- 2016-09-14 RU RU2018113435A patent/RU2749610C2/ru active
- 2016-09-14 IL IL313283A patent/IL313283B1/en unknown
- 2016-09-14 BR BR112018005180-2A patent/BR112018005180B1/pt active IP Right Grant
- 2016-09-14 ES ES16847253T patent/ES2923769T3/es active Active
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2018
- 2018-03-13 IL IL258071A patent/IL258071B/en unknown
- 2018-03-14 MX MX2022008806A patent/MX2022008806A/es unknown
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2021
- 2021-11-17 JP JP2021186960A patent/JP2022028818A/ja not_active Withdrawn
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2023
- 2023-07-27 AU AU2023208190A patent/AU2023208190A1/en active Pending
- 2023-11-28 JP JP2023200819A patent/JP2024019229A/ja active Pending
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