HUE053558T2 - Adenozin A3 receptor ligandum felhasználásra ektopikus zsírfelhalmozódás kezelésében - Google Patents

Adenozin A3 receptor ligandum felhasználásra ektopikus zsírfelhalmozódás kezelésében

Info

Publication number
HUE053558T2
HUE053558T2 HUE16806299A HUE16806299A HUE053558T2 HU E053558 T2 HUE053558 T2 HU E053558T2 HU E16806299 A HUE16806299 A HU E16806299A HU E16806299 A HUE16806299 A HU E16806299A HU E053558 T2 HUE053558 T2 HU E053558T2
Authority
HU
Hungary
Prior art keywords
receptor ligand
adenosine receptor
fat accumulation
ectopic fat
treating ectopic
Prior art date
Application number
HUE16806299A
Other languages
English (en)
Inventor
Pnina Fishman
Shira Cohen
Original Assignee
Can Fite Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Can Fite Biopharma Ltd filed Critical Can Fite Biopharma Ltd
Publication of HUE053558T2 publication Critical patent/HUE053558T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
HUE16806299A 2015-11-23 2016-11-22 Adenozin A3 receptor ligandum felhasználásra ektopikus zsírfelhalmozódás kezelésében HUE053558T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL242723A IL242723B (en) 2015-11-23 2015-11-23 A3 adenosine receptor ligand for the treatment of ectopic fat accumulation

Publications (1)

Publication Number Publication Date
HUE053558T2 true HUE053558T2 (hu) 2021-07-28

Family

ID=57485841

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16806299A HUE053558T2 (hu) 2015-11-23 2016-11-22 Adenozin A3 receptor ligandum felhasználásra ektopikus zsírfelhalmozódás kezelésében

Country Status (19)

Country Link
US (2) US10780106B2 (hu)
EP (1) EP3380104B1 (hu)
JP (2) JP6980655B2 (hu)
KR (1) KR102103657B1 (hu)
CN (1) CN108367016B (hu)
BR (1) BR112018010391A8 (hu)
CA (1) CA3005961C (hu)
DK (1) DK3380104T3 (hu)
ES (1) ES2848150T3 (hu)
HR (1) HRP20210020T1 (hu)
HU (1) HUE053558T2 (hu)
IL (3) IL242723B (hu)
LT (1) LT3380104T (hu)
MX (1) MX2018006026A (hu)
PL (1) PL3380104T3 (hu)
PT (1) PT3380104T (hu)
RS (1) RS61372B1 (hu)
SI (1) SI3380104T1 (hu)
WO (1) WO2017090036A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL254535A0 (en) * 2017-09-17 2017-11-30 Can Fite Biopharma Ltd Adenosine a3 receptor ligand for use in the management of cytokine release syndrome
IL264112A (en) * 2019-01-06 2020-07-30 Fishman Pnina Adenosine a3 receptor ligand for use in lowering adipocyte levels
IL272078A (en) 2020-01-16 2021-07-29 Can Fite Biopharma Ltd Cannabinoids for use in therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443836A (en) 1993-03-15 1995-08-22 Gensia, Inc. Methods for protecting tissues and organs from ischemic damage
US5688774A (en) 1993-07-13 1997-11-18 The United States Of America As Represented By The Department Of Health And Human Services A3 adenosine receptor agonists
US5773423A (en) 1993-07-13 1998-06-30 The United States Of America As Represented By The Department Of Health And Human Services A3 adenosine receptor agonists
AU1399297A (en) 1996-01-24 1997-08-20 Sumitomo Chemical Company, Limited Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production
JP2003517423A (ja) 1997-07-29 2003-05-27 メドコ リサーチ、インコーポレイテッド アデノシンレセプターモジュレーターとしてのn6−置換アデノシン−5′−ウロナミド
US6048865A (en) 1997-07-29 2000-04-11 Medco Research, Inc. N6 -substituted-adenosine-5'-uronamides as adenosine receptor modulator
WO1999020284A1 (en) 1997-10-23 1999-04-29 Trustees Of The University Of Pennsylvania Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid a and adenosine receptor agents
IL133680A0 (en) 1999-09-10 2001-04-30 Can Fite Technologies Ltd Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
JP4012070B2 (ja) * 2001-01-16 2007-11-21 カン−フィテ・バイオファーマ・リミテッド ウイルスの複製を阻害するためのアデノシンa3受容体アゴニストの使用
KR101383228B1 (ko) 2006-01-26 2014-04-09 더 가번먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 레프리젠티드 바이 더 세크러터리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비스즈 A3 아데노신 수용체 알로스테릭 조절제
EP2227234B1 (en) 2007-10-15 2014-05-07 Can-Fite Biopharma Ltd. Method for inducing hepatocyte proliferation and uses thereof
JP2015504088A (ja) * 2012-01-23 2015-02-05 キャン−ファイト バイオファーマ リミテッドCan−Fite BioPharma Ltd. 肝疾患の治療

Also Published As

Publication number Publication date
BR112018010391A8 (pt) 2019-02-26
US10780106B2 (en) 2020-09-22
BR112018010391A2 (pt) 2018-11-21
EP3380104B1 (en) 2020-11-11
US20180264022A1 (en) 2018-09-20
HRP20210020T1 (hr) 2021-03-05
RS61372B1 (sr) 2021-02-26
DK3380104T3 (da) 2021-02-08
CA3005961C (en) 2024-06-04
IL259396B (en) 2022-02-01
JP6980655B2 (ja) 2021-12-15
CN108367016B (zh) 2021-07-16
CN108367016A (zh) 2018-08-03
LT3380104T (lt) 2021-05-10
IL242723A0 (en) 2016-02-29
KR102103657B1 (ko) 2020-04-23
IL242723B (en) 2019-12-31
SI3380104T1 (sl) 2021-05-31
ES2848150T3 (es) 2021-08-05
US20200384009A1 (en) 2020-12-10
KR20180081595A (ko) 2018-07-16
PL3380104T3 (pl) 2021-08-02
IL289841B (en) 2022-07-01
US11291681B2 (en) 2022-04-05
JP2020090532A (ja) 2020-06-11
EP3380104A1 (en) 2018-10-03
JP2018534333A (ja) 2018-11-22
JP6990934B2 (ja) 2022-01-12
PT3380104T (pt) 2021-02-05
IL289841A (en) 2022-03-01
WO2017090036A1 (en) 2017-06-01
IL259396A (en) 2018-07-31
MX2018006026A (es) 2019-01-28
CA3005961A1 (en) 2017-06-01

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