DK3380104T3 - A3-adenosinreceptorligand til anvendelse i behandling af ektopisk fedtophobning - Google Patents

A3-adenosinreceptorligand til anvendelse i behandling af ektopisk fedtophobning Download PDF

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Publication number
DK3380104T3
DK3380104T3 DK16806299.0T DK16806299T DK3380104T3 DK 3380104 T3 DK3380104 T3 DK 3380104T3 DK 16806299 T DK16806299 T DK 16806299T DK 3380104 T3 DK3380104 T3 DK 3380104T3
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DK
Denmark
Prior art keywords
treatment
receptor ligand
fat accumulation
ectopic fat
adenosin
Prior art date
Application number
DK16806299.0T
Other languages
English (en)
Inventor
Pnina Fishman
Shira Cohen
Original Assignee
Can Fite Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Can Fite Biopharma Ltd filed Critical Can Fite Biopharma Ltd
Application granted granted Critical
Publication of DK3380104T3 publication Critical patent/DK3380104T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16806299.0T 2015-11-23 2016-11-22 A3-adenosinreceptorligand til anvendelse i behandling af ektopisk fedtophobning DK3380104T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL242723A IL242723B (en) 2015-11-23 2015-11-23 A3 adenosine receptor ligand for the treatment of ectopic fat accumulation
PCT/IL2016/051258 WO2017090036A1 (en) 2015-11-23 2016-11-22 An a3 adenosine receptor ligand for use in treating ectopic fat accumulation

Publications (1)

Publication Number Publication Date
DK3380104T3 true DK3380104T3 (da) 2021-02-08

Family

ID=57485841

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16806299.0T DK3380104T3 (da) 2015-11-23 2016-11-22 A3-adenosinreceptorligand til anvendelse i behandling af ektopisk fedtophobning

Country Status (19)

Country Link
US (2) US10780106B2 (da)
EP (1) EP3380104B1 (da)
JP (2) JP6980655B2 (da)
KR (1) KR102103657B1 (da)
CN (1) CN108367016B (da)
BR (1) BR112018010391A8 (da)
CA (1) CA3005961C (da)
DK (1) DK3380104T3 (da)
ES (1) ES2848150T3 (da)
HR (1) HRP20210020T1 (da)
HU (1) HUE053558T2 (da)
IL (3) IL242723B (da)
LT (1) LT3380104T (da)
MX (1) MX2018006026A (da)
PL (1) PL3380104T3 (da)
PT (1) PT3380104T (da)
RS (1) RS61372B1 (da)
SI (1) SI3380104T1 (da)
WO (1) WO2017090036A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL254535A0 (en) * 2017-09-17 2017-11-30 Can Fite Biopharma Ltd Adenosine a3 receptor ligand for use in the management of cytokine release syndrome
IL264112A (en) * 2019-01-06 2020-07-30 Fishman Pnina Adenosine a3 receptor ligand for use in lowering adipocyte levels
IL272078A (en) 2020-01-16 2021-07-29 Can Fite Biopharma Ltd Cannabinoids for use in therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443836A (en) 1993-03-15 1995-08-22 Gensia, Inc. Methods for protecting tissues and organs from ischemic damage
US5688774A (en) 1993-07-13 1997-11-18 The United States Of America As Represented By The Department Of Health And Human Services A3 adenosine receptor agonists
EP0708781B1 (en) 1993-07-13 2001-10-04 THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services A 3 adenosine receptor agonists
WO1997027173A2 (en) 1996-01-24 1997-07-31 Sumitomo Chemical Company, Limited Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production
US6048865A (en) 1997-07-29 2000-04-11 Medco Research, Inc. N6 -substituted-adenosine-5'-uronamides as adenosine receptor modulator
EP1019427A4 (en) 1997-07-29 2000-07-19 Medco Res Inc N? 6 -SUBSTITUES-ADENOSINE-5'-URONAMIDES USEFUL AS MODULATORS OF ADENOSINE RECEPTORS
WO1999020284A1 (en) 1997-10-23 1999-04-29 Trustees Of The University Of Pennsylvania Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid a and adenosine receptor agents
IL133680A0 (en) 1999-09-10 2001-04-30 Can Fite Technologies Ltd Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
CA2434906C (en) * 2001-01-16 2008-08-19 Can-Fite Biopharma Ltd. Use of an adenosine a3 receptor agonist for inhibition of viral replication
EP1983990B1 (en) 2006-01-26 2011-03-23 Government of the United States of America, Represented by the Secretary, Department of Health and Human Services A3 adenosine receptor allosteric modulators
DK2227234T3 (da) * 2007-10-15 2014-08-11 Can Fite Biopharma Ltd Fremgangsmåde til induktion af hepatocytproliferering og anvendelserderaf
US20150018299A1 (en) 2012-01-23 2015-01-15 Can-Fite Biopharma Ltd. Treatment of liver conditions

Also Published As

Publication number Publication date
BR112018010391A8 (pt) 2019-02-26
WO2017090036A1 (en) 2017-06-01
LT3380104T (lt) 2021-05-10
PL3380104T3 (pl) 2021-08-02
IL289841B (en) 2022-07-01
PT3380104T (pt) 2021-02-05
ES2848150T3 (es) 2021-08-05
HRP20210020T1 (hr) 2021-03-05
CA3005961C (en) 2024-06-04
IL242723A0 (en) 2016-02-29
US11291681B2 (en) 2022-04-05
KR102103657B1 (ko) 2020-04-23
US10780106B2 (en) 2020-09-22
HUE053558T2 (hu) 2021-07-28
JP2020090532A (ja) 2020-06-11
IL242723B (en) 2019-12-31
JP6980655B2 (ja) 2021-12-15
IL259396A (en) 2018-07-31
IL289841A (en) 2022-03-01
MX2018006026A (es) 2019-01-28
CN108367016A (zh) 2018-08-03
US20180264022A1 (en) 2018-09-20
EP3380104B1 (en) 2020-11-11
JP2018534333A (ja) 2018-11-22
BR112018010391A2 (pt) 2018-11-21
KR20180081595A (ko) 2018-07-16
JP6990934B2 (ja) 2022-01-12
CN108367016B (zh) 2021-07-16
IL259396B (en) 2022-02-01
CA3005961A1 (en) 2017-06-01
SI3380104T1 (sl) 2021-05-31
US20200384009A1 (en) 2020-12-10
RS61372B1 (sr) 2021-02-26
EP3380104A1 (en) 2018-10-03

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