HUE050975T2 - Adapter-asszociált kináz 1 inhibitorai, azokat tartalmazó kompozíciók és eljárások alkalmazásukra - Google Patents
Adapter-asszociált kináz 1 inhibitorai, azokat tartalmazó kompozíciók és eljárások alkalmazásukraInfo
- Publication number
- HUE050975T2 HUE050975T2 HUE15712026A HUE15712026A HUE050975T2 HU E050975 T2 HUE050975 T2 HU E050975T2 HU E15712026 A HUE15712026 A HU E15712026A HU E15712026 A HUE15712026 A HU E15712026A HU E050975 T2 HUE050975 T2 HU E050975T2
- Authority
- HU
- Hungary
- Prior art keywords
- inhibitors
- compositions
- methods
- associated kinase
- adapter associated
- Prior art date
Links
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953976P | 2014-03-17 | 2014-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE050975T2 true HUE050975T2 (hu) | 2021-01-28 |
Family
ID=52727478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE15712026A HUE050975T2 (hu) | 2014-03-17 | 2015-03-16 | Adapter-asszociált kináz 1 inhibitorai, azokat tartalmazó kompozíciók és eljárások alkalmazásukra |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9682982B2 (enExample) |
| EP (2) | EP3119783B1 (enExample) |
| JP (1) | JP6553081B2 (enExample) |
| CN (1) | CN106103447B (enExample) |
| AR (1) | AR099766A1 (enExample) |
| AU (1) | AU2015231672B2 (enExample) |
| CA (1) | CA2941870C (enExample) |
| DK (2) | DK3119783T3 (enExample) |
| ES (2) | ES2911388T3 (enExample) |
| HU (1) | HUE050975T2 (enExample) |
| PL (2) | PL3119783T3 (enExample) |
| PT (2) | PT3719021T (enExample) |
| TW (1) | TW201620911A (enExample) |
| WO (1) | WO2015142714A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104302649B (zh) * | 2012-03-09 | 2017-06-23 | 莱西肯医药有限公司 | 基于吡唑并[1,5‑a]嘧啶的化合物、包含它们的组合物及其使用方法 |
| JP6473146B2 (ja) | 2013-10-11 | 2019-02-20 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ピロロトリアジンキナーゼ阻害剤 |
| CN109369576B (zh) * | 2018-09-19 | 2020-11-27 | 上海凌凯医药科技有限公司 | 一种合成3-甲基氧杂环丁烷-3-(4-硝基苯基)碳酸酯的方法 |
| US11730723B2 (en) | 2020-04-21 | 2023-08-22 | Lexicon Pharmaceuticals, Inc. | Compounds and methods for treating viral infections |
| CN115427045A (zh) * | 2020-04-21 | 2022-12-02 | 莱西肯医药有限公司 | 用于治疗cov-229e或cov-oc43冠状病毒感染的4-(3-(吡啶-3-基)吡唑并[1，5-a]嘧啶-5-基)哌嗪 |
| WO2023196584A2 (en) * | 2022-04-08 | 2023-10-12 | New York University | Endocytosis inhibitors and their use for pain treatment |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| US6194410B1 (en) * | 1998-03-11 | 2001-02-27 | Hoffman-La Roche Inc. | Pyrazolopyrimidine and pyrazolines and process for preparation thereof |
| EP1873157A1 (en) * | 2006-06-21 | 2008-01-02 | Bayer Schering Pharma Aktiengesellschaft | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
| WO2010118207A1 (en) * | 2009-04-09 | 2010-10-14 | Schering Corporation | Pyrazolo [1, 5-a] pyrimidine derivatives as mtor inhibitors |
| UA110324C2 (en) * | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
| WO2011030139A1 (en) * | 2009-09-11 | 2011-03-17 | Astrazeneca Ab | 4- (pyrimidin-2-yl) -piperazine and 4- (pyrimidin-2-yl) -piperidine derivatives as gpr119 modulators |
| WO2011087999A1 (en) * | 2010-01-14 | 2011-07-21 | Merck Sharp & Dohme Corp. | Pyrazolo[1,5-a]pyrimidines as mark inhibitors |
| WO2012034095A1 (en) * | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| HUE036040T2 (hu) * | 2012-03-09 | 2018-06-28 | Lexicon Pharmaceuticals Inc | Adaptor-asszociált kináz 1 gátlása fájdalom kezelésére |
| CN104302649B (zh) | 2012-03-09 | 2017-06-23 | 莱西肯医药有限公司 | 基于吡唑并[1,5‑a]嘧啶的化合物、包含它们的组合物及其使用方法 |
| US8969565B2 (en) * | 2012-03-09 | 2015-03-03 | Lexicon Pharmaceuticals, Inc. | Imidazo[1,2-b]pyridazine-based compounds, compositions comprising them, and methods of their use |
-
2015
- 2015-03-04 TW TW104106872A patent/TW201620911A/zh unknown
- 2015-03-16 EP EP15712026.2A patent/EP3119783B1/en active Active
- 2015-03-16 PL PL15712026T patent/PL3119783T3/pl unknown
- 2015-03-16 JP JP2016557251A patent/JP6553081B2/ja active Active
- 2015-03-16 CA CA2941870A patent/CA2941870C/en active Active
- 2015-03-16 PT PT201776044T patent/PT3719021T/pt unknown
- 2015-03-16 AU AU2015231672A patent/AU2015231672B2/en active Active
- 2015-03-16 DK DK15712026.2T patent/DK3119783T3/da active
- 2015-03-16 DK DK20177604.4T patent/DK3719021T3/da active
- 2015-03-16 AR ARP150100787A patent/AR099766A1/es unknown
- 2015-03-16 PT PT157120262T patent/PT3119783T/pt unknown
- 2015-03-16 CN CN201580014255.6A patent/CN106103447B/zh active Active
- 2015-03-16 ES ES20177604T patent/ES2911388T3/es active Active
- 2015-03-16 WO PCT/US2015/020696 patent/WO2015142714A1/en not_active Ceased
- 2015-03-16 PL PL20177604T patent/PL3719021T3/pl unknown
- 2015-03-16 ES ES15712026T patent/ES2821441T3/es active Active
- 2015-03-16 US US14/658,653 patent/US9682982B2/en active Active
- 2015-03-16 HU HUE15712026A patent/HUE050975T2/hu unknown
- 2015-03-16 EP EP20177604.4A patent/EP3719021B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN106103447B (zh) | 2019-07-16 |
| EP3119783B1 (en) | 2020-06-24 |
| JP6553081B2 (ja) | 2019-07-31 |
| AU2015231672A1 (en) | 2016-09-15 |
| EP3719021B1 (en) | 2022-03-09 |
| DK3719021T3 (da) | 2022-06-13 |
| HK1226065A1 (zh) | 2017-09-22 |
| PT3119783T (pt) | 2020-09-24 |
| PL3119783T3 (pl) | 2021-01-11 |
| EP3719021A1 (en) | 2020-10-07 |
| ES2821441T3 (es) | 2021-04-26 |
| PT3719021T (pt) | 2022-04-08 |
| US9682982B2 (en) | 2017-06-20 |
| US20160039824A1 (en) | 2016-02-11 |
| CA2941870A1 (en) | 2015-09-24 |
| TW201620911A (zh) | 2016-06-16 |
| DK3119783T3 (da) | 2020-09-28 |
| JP2017507980A (ja) | 2017-03-23 |
| CA2941870C (en) | 2022-07-19 |
| CN106103447A (zh) | 2016-11-09 |
| EP3119783A1 (en) | 2017-01-25 |
| AU2015231672B2 (en) | 2019-06-20 |
| ES2911388T3 (es) | 2022-05-19 |
| WO2015142714A1 (en) | 2015-09-24 |
| PL3719021T3 (pl) | 2022-06-20 |
| AR099766A1 (es) | 2016-08-17 |
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