HUE042720T2 - Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén - Google Patents

Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén

Info

Publication number
HUE042720T2
HUE042720T2 HUE12813295A HUE12813295A HUE042720T2 HU E042720 T2 HUE042720 T2 HU E042720T2 HU E12813295 A HUE12813295 A HU E12813295A HU E12813295 A HUE12813295 A HU E12813295A HU E042720 T2 HUE042720 T2 HU E042720T2
Authority
HU
Hungary
Prior art keywords
preventing
methods
inhibiting binding
treating certain
certain disorders
Prior art date
Application number
HUE12813295A
Other languages
English (en)
Hungarian (hu)
Inventor
Andreas Hohlbaum
Laurent Audoly
Beverly Koller
Original Assignee
Pieris Pharmaceuticals Gmbh
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieris Pharmaceuticals Gmbh, Astrazeneca Ab filed Critical Pieris Pharmaceuticals Gmbh
Publication of HUE042720T2 publication Critical patent/HUE042720T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
HUE12813295A 2011-12-13 2012-12-12 Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén HUE042720T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161570018P 2011-12-13 2011-12-13

Publications (1)

Publication Number Publication Date
HUE042720T2 true HUE042720T2 (hu) 2019-07-29

Family

ID=47552959

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE12813295A HUE042720T2 (hu) 2011-12-13 2012-12-12 Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén
HUE18197286A HUE054342T2 (hu) 2011-12-13 2012-12-12 Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére render IL-4 és/vagy IL-13 receptorához történõ kötõdésének gátlásával

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE18197286A HUE054342T2 (hu) 2011-12-13 2012-12-12 Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére render IL-4 és/vagy IL-13 receptorához történõ kötõdésének gátlásával

Country Status (13)

Country Link
US (6) US9572863B2 (cg-RX-API-DMAC7.html)
EP (3) EP2790719B1 (cg-RX-API-DMAC7.html)
JP (5) JP6163162B2 (cg-RX-API-DMAC7.html)
CN (2) CN109432402B (cg-RX-API-DMAC7.html)
AU (1) AU2012350660B2 (cg-RX-API-DMAC7.html)
CA (1) CA2858962C (cg-RX-API-DMAC7.html)
DK (2) DK3453400T3 (cg-RX-API-DMAC7.html)
ES (2) ES2863410T3 (cg-RX-API-DMAC7.html)
HU (2) HUE042720T2 (cg-RX-API-DMAC7.html)
PL (2) PL3453400T3 (cg-RX-API-DMAC7.html)
SG (2) SG10201604566QA (cg-RX-API-DMAC7.html)
TR (1) TR201901826T4 (cg-RX-API-DMAC7.html)
WO (1) WO2013087660A1 (cg-RX-API-DMAC7.html)

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US8986951B2 (en) * 2010-06-08 2015-03-24 Pieris Ag Tear lipocalin in muteins binding IL-4 R alpha
TR201901826T4 (tr) * 2011-12-13 2019-03-21 Astrazeneca Ab Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler.
SG10201912019WA (en) * 2014-05-22 2020-02-27 Pieris Pharmaceuticals Gmbh Novel specific-binding polypeptides and uses thereof
JP7108535B2 (ja) 2015-07-15 2022-07-28 ピエリス ファーマシューティカルズ ゲーエムベーハー Lag-3に特異的な新規タンパク質
CN113372446A (zh) * 2016-06-08 2021-09-10 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
KR20190104409A (ko) 2017-01-18 2019-09-09 피어이스 파마슈티컬즈 게엠베하 Lag-3에 대하여 결합 친화성을 갖는 리포칼린 뮤테인
AU2018254542B2 (en) * 2017-04-21 2022-12-22 Elanco Us Inc. IL4/IL13 receptor molecule for veterinary use
CN111494625B (zh) 2018-12-25 2022-06-21 江苏荃信生物医药股份有限公司 用于治疗il-4和/或il-13介导的信号转导相关的疾病的药物组合物
SG11202109839YA (en) 2019-03-29 2021-10-28 Astrazeneca Ab Lipocalin mutein for treatment of asthma
CA3127973A1 (en) * 2019-03-29 2020-10-08 Pieris Pharmaceuticals Gmbh Inhaled administration of lipocalin muteins
CR20230265A (es) 2020-12-18 2023-09-29 Astrazeneca Ab Formulación de polvo seco de muteína de lipocalina para el tratamiento del asma
CN115414467B (zh) * 2022-10-14 2023-06-06 中国人民解放军陆军军医大学第二附属医院 载脂蛋白d在制备治疗脑出血药物中的用途

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FR2649991B2 (fr) 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
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WO2003029462A1 (en) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
AU2001298053A1 (en) 2001-09-27 2003-04-14 Pieris Proteolab Ag Muteins of apolipoprotein D
AU2003233583A1 (en) * 2002-05-24 2003-12-12 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
US7691970B2 (en) 2003-08-25 2010-04-06 Pieris Ag Muteins of a bilin-binding protein with affinity for a given target
AU2003275958A1 (en) 2003-08-25 2005-03-10 Pieris Proteolab Ag Muteins of tear lipocalin
RU2389796C2 (ru) 2003-08-29 2010-05-20 Аэровэнс, Инк. Модифицированный антагонист рецептора il-4 и предназначенный для его получения очищенный полинуклеотид
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US8598317B2 (en) 2006-03-20 2013-12-03 Technische Universitaet Muenchen Muteins of tear lipocalin with affinity for the T-cell coreceptor CD4
JP5608368B2 (ja) 2006-08-01 2014-10-15 ピエリス アーゲー 涙リポカリンの突然変異タンパク質およびそれを得るための方法
KR20100047866A (ko) * 2007-07-11 2010-05-10 애로반스, 인코포레이티드 약제학적 폴리펩타이드 건조 분말 에어로졸 제형 및 이의 제조 방법
US8986951B2 (en) 2010-06-08 2015-03-24 Pieris Ag Tear lipocalin in muteins binding IL-4 R alpha
TR201901826T4 (tr) 2011-12-13 2019-03-21 Astrazeneca Ab Il-4 ve/veya ıl-13'ün ilgili reseptörlerine bağlanmasını inhibe ederek belirli rahatsızlıkların önlenmesi ya da tedavi edilmesi için yöntemler.

Also Published As

Publication number Publication date
JP2019116499A (ja) 2019-07-18
EP2790719B1 (en) 2018-11-21
JP6889201B2 (ja) 2021-06-18
EP3453400A1 (en) 2019-03-13
TR201901826T4 (tr) 2019-03-21
EP3453400B1 (en) 2021-01-20
CN103998053B9 (zh) 2020-07-21
US11382951B2 (en) 2022-07-12
US20200009223A1 (en) 2020-01-09
JP6163162B2 (ja) 2017-07-12
EP3842058A1 (en) 2021-06-30
PL3453400T3 (pl) 2021-08-09
US20210145934A1 (en) 2021-05-20
US20230021168A1 (en) 2023-01-19
US10398754B2 (en) 2019-09-03
ES2710384T3 (es) 2019-04-24
SG11201402992SA (en) 2014-07-30
US10016483B2 (en) 2018-07-10
JP6725447B2 (ja) 2020-07-15
US20190030121A1 (en) 2019-01-31
JP2015505303A (ja) 2015-02-19
EP3842058B1 (en) 2023-08-23
EP2790719A1 (en) 2014-10-22
PL2790719T3 (pl) 2019-05-31
CA2858962C (en) 2023-09-05
JP2022084854A (ja) 2022-06-07
US20170112900A1 (en) 2017-04-27
CN109432402B (zh) 2022-04-29
CN109432402A (zh) 2019-03-08
CA2858962A1 (en) 2013-06-20
DK2790719T3 (en) 2019-02-11
HUE054342T2 (hu) 2021-08-30
US10857202B2 (en) 2020-12-08
JP2020164532A (ja) 2020-10-08
JP7441589B2 (ja) 2024-03-01
CN103998053B (zh) 2018-11-02
JP2017149733A (ja) 2017-08-31
SG10201604566QA (en) 2016-07-28
US9572863B2 (en) 2017-02-21
WO2013087660A1 (en) 2013-06-20
DK3453400T3 (da) 2021-04-06
ES2863410T3 (es) 2021-10-11
AU2012350660A1 (en) 2014-07-03
CN103998053A (zh) 2014-08-20
AU2012350660B2 (en) 2018-01-25
US20140357548A1 (en) 2014-12-04

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