HUE037266T2 - Új pirrolopirimidinvegyületek vagy sóik, az azokat tartalmazó gyógyászati készítmény, különösen NAE inhibitor hatáson alapuló tumorok stb. megelõzésére és/vagy kezelésére szolgáló szer - Google Patents

Új pirrolopirimidinvegyületek vagy sóik, az azokat tartalmazó gyógyászati készítmény, különösen NAE inhibitor hatáson alapuló tumorok stb. megelõzésére és/vagy kezelésére szolgáló szer

Info

Publication number
HUE037266T2
HUE037266T2 HUE15811341A HUE15811341A HUE037266T2 HU E037266 T2 HUE037266 T2 HU E037266T2 HU E15811341 A HUE15811341 A HU E15811341A HU E15811341 A HUE15811341 A HU E15811341A HU E037266 T2 HUE037266 T2 HU E037266T2
Authority
HU
Hungary
Prior art keywords
prevention
salt
treatment
pharmaceutical composition
composition containing
Prior art date
Application number
HUE15811341A
Other languages
English (en)
Hungarian (hu)
Inventor
Takashi Mizutani
Chihoko Yoshimura
Hitomi Kondo
Makoto Kitade
Shuichi Ohkubo
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of HUE037266T2 publication Critical patent/HUE037266T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HUE15811341A 2014-06-24 2015-06-24 Új pirrolopirimidinvegyületek vagy sóik, az azokat tartalmazó gyógyászati készítmény, különösen NAE inhibitor hatáson alapuló tumorok stb. megelõzésére és/vagy kezelésére szolgáló szer HUE037266T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014129740 2014-06-24
JP2015024785 2015-02-10

Publications (1)

Publication Number Publication Date
HUE037266T2 true HUE037266T2 (hu) 2018-08-28

Family

ID=54938214

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15811341A HUE037266T2 (hu) 2014-06-24 2015-06-24 Új pirrolopirimidinvegyületek vagy sóik, az azokat tartalmazó gyógyászati készítmény, különösen NAE inhibitor hatáson alapuló tumorok stb. megelõzésére és/vagy kezelésére szolgáló szer

Country Status (21)

Country Link
US (2) US9963456B2 (enExample)
EP (1) EP3103802B1 (enExample)
JP (1) JP6192741B2 (enExample)
KR (1) KR101947289B1 (enExample)
CN (1) CN106661031B (enExample)
AU (1) AU2015281155B9 (enExample)
BR (1) BR112016025835B1 (enExample)
CA (1) CA2946833C (enExample)
DK (1) DK3103802T3 (enExample)
ES (1) ES2656772T3 (enExample)
HU (1) HUE037266T2 (enExample)
MX (1) MX2016015015A (enExample)
MY (1) MY183327A (enExample)
NO (1) NO3103802T3 (enExample)
PH (1) PH12016502130B1 (enExample)
PL (1) PL3103802T3 (enExample)
PT (1) PT3103802T (enExample)
RU (1) RU2658008C2 (enExample)
SG (1) SG11201608441YA (enExample)
TW (1) TWI605048B (enExample)
WO (1) WO2015199136A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI623316B (zh) * 2015-12-22 2018-05-11 Taiho Pharmaceutical Co Ltd Antitumor effect enhancer derived from pyrrolopyrimidine compound
WO2018085818A1 (en) * 2016-11-07 2018-05-11 Prelude Therapeutics, Incorporated Selective inhibitors of protein arginine methyltransferase 5 (prmt5)
WO2018085833A2 (en) * 2016-11-07 2018-05-11 Prelude Therapeutics, Incorporated Selective inhibitors of protein arginine methyl transferase 5 (prmt5)
WO2018089786A1 (en) * 2016-11-11 2018-05-17 Millennium Pharmaceuticals, Inc. Atg7 inhibitors and the uses thereof
WO2018110591A1 (ja) * 2016-12-13 2018-06-21 ヤマサ醤油株式会社 抗ウイルス活性を有する2'-デオキシ-7-デアザプリンヌクレオシド誘導体
TWI802635B (zh) * 2018-01-18 2023-05-21 美商亞雷生物製藥股份有限公司 作為ret激酶抑制劑之經取代吡咯并[2,3-d]嘧啶化合物
CN108640945B (zh) * 2018-06-11 2020-10-23 广东工业大学 一种酰胺类化合物及其制备方法与应用
CN108822145B (zh) * 2018-06-11 2020-10-23 广东工业大学 一种磺酰胺类化合物及其制备方法和应用
CN113382754A (zh) * 2018-07-13 2021-09-10 Il-2Rx公司 治疗癌症和免疫病症的化合物、组合物、方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1848718T1 (sl) * 2005-02-04 2012-12-31 Millennium Pharmaceuticals, Inc. Inhibitorji E1 aktivacijskih enzimov
US7989430B2 (en) 2005-12-06 2011-08-02 Regents Of The University Of Minnesota Antibacterial agents
ES2593433T3 (es) 2006-02-02 2016-12-09 Millennium Pharmaceuticals, Inc. Inhibidores de las enzimas activadoras E1
US20120115892A1 (en) * 2010-11-05 2012-05-10 Millennium Pharmaceuticals, Inc. Administration of nedd8-activating enzyme inhibitor
CN103298817A (zh) 2011-01-07 2013-09-11 利奥制药有限公司 作为蛋白酪氨酸激酶抑制剂的新磺酰胺哌嗪衍生物及其药物用途
EP2738873A4 (en) * 2011-07-29 2015-04-01 Kuang Chi Innovative Tech Ltd ARTIFICIAL COMPOSITE MATERIAL AND ANTENNA PRODUCED FROM ARTIFICIAL COMPOSITE MATERIAL
CN103958512B (zh) * 2012-01-19 2016-01-20 大鹏药品工业株式会社 3,5-双取代炔基苯化合物及其盐

Also Published As

Publication number Publication date
CN106661031A (zh) 2017-05-10
KR20170016510A (ko) 2017-02-13
PT3103802T (pt) 2017-12-11
KR101947289B1 (ko) 2019-02-12
DK3103802T3 (en) 2017-12-11
US9963456B2 (en) 2018-05-08
PH12016502130A1 (en) 2016-12-19
CN106661031B (zh) 2019-07-23
US20170066772A1 (en) 2017-03-09
PL3103802T3 (pl) 2018-02-28
TW201625629A (zh) 2016-07-16
SG11201608441YA (en) 2016-11-29
MY183327A (en) 2021-02-18
JPWO2015199136A1 (ja) 2017-04-27
CA2946833A1 (en) 2015-12-30
PH12016502130B1 (en) 2016-12-19
WO2015199136A1 (ja) 2015-12-30
US20180162864A1 (en) 2018-06-14
EP3103802A1 (en) 2016-12-14
EP3103802B1 (en) 2017-11-08
BR112016025835B1 (pt) 2022-09-20
US10174040B2 (en) 2019-01-08
RU2658008C2 (ru) 2018-06-19
MX2016015015A (es) 2017-02-27
JP6192741B2 (ja) 2017-09-06
AU2015281155A1 (en) 2016-11-03
BR112016025835A2 (enExample) 2017-08-15
AU2015281155B2 (en) 2017-07-13
CA2946833C (en) 2019-03-05
RU2016149319A3 (enExample) 2018-06-18
ES2656772T3 (es) 2018-02-28
RU2016149319A (ru) 2018-06-18
EP3103802A4 (en) 2017-03-08
AU2015281155B9 (en) 2017-11-16
TWI605048B (zh) 2017-11-11
NO3103802T3 (enExample) 2018-04-07

Similar Documents

Publication Publication Date Title
IL264049A (en) Compounds, preparations and methods for treating the disease
SG11201608441YA (en) Novel pyrrolopyrimidine compound or salt thereof, pharmaceutical composition containing same, especially agent for prevention and/or treatment of tumors etc based on nae inhibitory effect
IL254722A0 (en) Indoleamine 3,2-dioxygenase inhibitors for cancer treatment
IL264156A (en) Compounds, preparations and methods for treating the disease
PL3672954T3 (pl) Związki, ich sole i ich zastosowanie w leczeniu chorób
PL3065732T3 (pl) Związki, kompozycje i odpowiednie zastosowania do zapobiegania i/lub leczenia dyslipidemii
IL263697A (en) Compounds, preparations and methods for the treatment and/or prevention of cancer
HK1243935A1 (zh) 有机化合物
ZA201707951B (en) Amide compound and use thereof as agent for the treatment and prevention of diseases caused by rna- and/or dna-containing viruses, and concomitant diseases
EP3231436A4 (en) Pharmaceutical composition for prevention or treatment of metabolic disease, comprising bacteroides acidifaciens as effective ingredient
IL263793A (en) Compounds and preparations for the treatment of cancer
EP3241551A4 (en) Pharmaceutical composition for treating cancer, containing lactate metal salt
HK1254231A1 (zh) 米托-和厚朴酚化合物及其合成方法和用途
IL275525A (en) A pharmaceutical preparation for the treatment of cancer
EP3148570A4 (en) Pharmaceutical composition for preventing or treating skin rash
EP3162803A4 (en) New compound for inhibiting binding between dx2 protein and p14/arf protein, and pharmaceutical composition for treating or preventing cancer disease containing same as effective ingredient
HK1243936A1 (zh) 有机化合物
EP3677267A4 (en) PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF TUMORS, METHOD AND USES THEREOF
EP3290051A4 (en) Pharmaceutical composition for treating and/or preventing cancer
PL3236961T3 (pl) Kompozycja farmaceutyczna do zapobiegania lub leczenia nowotworu złośliwego
EP3235808A4 (en) Modified taurine, and pharmaceutical composition for preventing or treating metabolic diseases containing same
IL252487A0 (en) Arylalkylamine compounds for use in the prevention or treatment of cancer
EP3267992A4 (en) Hypoestoxide, derivatives, related compounds, and agonists thereof for treatment or prevention of neurodegenerative diseases
EP3219323B8 (en) Pharmaceutical composition for treatment and/or prevention of hepatitis c
HK1235391A1 (en) Inhibitors of creatine transport and uses thereof