HUE032387T2 - Nagyon alacsony molekulatömegû polimereket tartalmazó nyújtott felszabadulású készítmények - Google Patents
Nagyon alacsony molekulatömegû polimereket tartalmazó nyújtott felszabadulású készítmények Download PDFInfo
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- HUE032387T2 HUE032387T2 HUE07819363A HUE07819363A HUE032387T2 HU E032387 T2 HUE032387 T2 HU E032387T2 HU E07819363 A HUE07819363 A HU E07819363A HU E07819363 A HUE07819363 A HU E07819363A HU E032387 T2 HUE032387 T2 HU E032387T2
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Claims (4)
- Saahadaimi igénypontok \ni ** t e* «aaeftntei tiVah vita**.\· e g-siiüoKee no e''"· a ' ok 'a tali' *z a) egy Je?J&k!M£$^:-nagyon alaesorty moiekutemegâ bkidegs-adàih&iô polimer* «Ä keverékét* amelynek tftrneg. «zerfati teopes osniekviaibnisge SüiMbbÛ Date» b) legalább :egy· hidnsnyagot vagy-eæek keverékét s. következő listából kiválasztva; ^^tidv pöb^gptid, protein., például imeinlaàlê homion (LHRH). p»jzsmsig> Ahrnilâlô hormon fïSRk kksxô sisfoulâlô hormon (FSH), pæratÎroid hormon (P?V%. 'tofc. '»övékedé·*» temm* növekedés! hpmxmt fôîssÂdtM kormon (QHRftk növekedési hormont teísxnbadiió pepiid, katotem és.«««« vegystleiek gyágyszerésxetiíeg elfogadható sói vagy ezek frognieosd, amely készítmény hozzáadott Mgitósxerek, lâgvhôsxerek, oidásxerefc vagy adalékanyagok nélkül vas éibálihva; és a lázárt lásycvégő hagytm slaesony taoieMattiis*# !>h>áspa#Ö«»ó· pföHa^í^iík^elim^ Ct-C'ss alkiksopomai vsa lezárva esnek karbonsav IÉíí««égzóddse bolyét*» és pohi laktid-ke-ghk:oliid)ok peliíejsav&k, po!l(giikoísavák) és exbk&vsrékes Rbxaí -«lifcm 2 A? L igénypont szerinti nyújtott feh.ssbadniású íeiig-sziklrd készkény, ahol &?. alkiksoporí egy 5-12 svêbîfosîoî tartalmazd á%lf#öp*fc 4 A,·· 1 s.*g\ ' s..,eí-'<p<'. ni mt-nis nvnjîoti félszabadulásó leiig-sztlárd készitény, ahol &;< sikiiesopott egy s sv..>; ü >mot tartatra» alknem \«s
- 4. Az l·? igénypontok bármelyike· Retint» nymimt: fclvahadttlátts féUg-a/ilatd kesxíiény, simbysllligy -szilárd késxiunens előállításánál a meglelde aihdmazoisi InkktiUs* hőmérséklet l>>0:'€ kbzöti van, 5. Λ 4. igénypont szerinu nyújtói; felvahadttüssö iekg-srilsrd ké*x:hény, amely·kásgítmátiy s:ioa *m ntl * nvetek ><. < L- s, ,.-= « - ! i s. o v, fi R tó > wxoíi sut 4 be í igénypont mono nsmtotí tets»\ät\5dnkkm tehg-s-xílúKi ksseneny- aboi a poim\i \agv I oponme; n i>k4 okbOiiKgr 740- 'Ogp lomon Won saa, előnyösen bob-ioon Halton kO,o't van. \ Λ* i igénypont ?*e««t} g>egy ^/etkészitnam^ nmek kvsrmnény nab>a»yap::r^öÄi»Äs.|j^8teÄ' vefcedást Hotmon t'tfcOH) vagy növekedési hormont tetebadhö bonbon (<GHRRt, srnmfinsxeró növekedési faktorok:{RïF-ekl, példán! lölAÍ, és kiíeinieiki bortnon (UiilH). 4 A -^:¾^ niniy tisgibÄy bstbspyap: imkontbbilbs teÄRPäf: nkii μ osnu hüo, vtys nbsek^eN, ·, no J.p i iou v ί I Ί1 ^ v \eOx'xO U ti \V\\ v. k'x \ \\ J'C \ x' tOV< X M'U! 1' I. V» $MvX &>·>«> saerésaebleg elfogadható s4ja 10. A '?, igénvpooi izcrími gyôgyaxerk'hîJtmény, amelv kászitmám hatóanyaga intetdlgájNI' Joioort: (LMK.H î e? ennek gyôgy.TaerA>veîsleg elfogadhat sûps.
- 11. Ae 1-12.. îgènypom sxennti g>4igyar.eFkesxÈfmè»y< amely készihaeö) «: »&·· m«g%, elönyíhen A.S-30 rbrnegA«. elbnyö&ebhe« 2-20 tbinegH tartományba esô nietrft$fsf$b*8 tártál»®«« ' ' t b»** 1 ' *£«>»' ,v « s >".vi î>',' x/»L J >. va» x» o» kevmoin} eíőof Inasat«* «^-artfe- mrtm?- maxes .a kimeikexh lépésekéi: a) & hatdaovagoi és a polimert bevsaetjbk kvd kulbnbözó fecskendőbe és hozzbUlesz^l^.a'SxsvÄdyöKÄ, bra kes megtöltött fecskendőt eg y 3 Irttpos rozsdamentes csatlakozóval csatlakoztatni:* » t « hato*» )¾ î. » tobsiut *.xkc tabol s akuto afett eltávolítjuk a levegőt, d) a ket komponenst & két ieocketulô között keverési eíjftrássai összekeverj» 13. A \2 igénypont »rittst eljárés,,atzssl: jellemezve, hogy £#£&&-esÄ»; ^AtSf^klNôÂt 'Sbaiwvat ! eme, exlv en Jet vbsost xAthaKVitersexA'* ' ségwzok
- 14. Eljárás az 1. igénypont szerint; fellgAkilárd gyóg^Z^|ssáitósyidl«álíllá^^:í^g^í.latóySl«^''a: következő kipèsekei; a) a polimert egy követőben ősszékevesjllfe b,î hatóanyagot adónk hozzá, e) a koo>pöoeHsek#k«sob&hömdfeskjei«», φφ esegjeR S*C és *P?£'kőZÖtó· ssÄlpaitMm#s&Äö' összekeverjek; 15 A 14. igénypont szerinti eljárás, azzal jellemezve* begy a hatóanyag por tormában van, Sé Gÿôgyszeïkeszionény,amely elMilíihatőa t-4 IS. igénypontok bármelyik« szerinti eljárással. iÊJm I. igénypont szÂI'ftyg^ista&dàte. M^ÍEÍiyi:%teíMayr *a»|rny$ti& IM«kâ& jg*,d Készítmény a festőanyagot legalább egy hèt âiaibJonyAscst legalább egy honsp alatt szsfeoltja fêlgamikor « fôijg-salâ«i kásztaaényt viz^Âl^iàS'Â^s^te^dc be.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06291679A EP1917971A1 (en) | 2006-10-27 | 2006-10-27 | Substained release formulations comprising very low molecular weight polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE032387T2 true HUE032387T2 (hu) | 2017-09-28 |
Family
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Family Applications (1)
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| HUE07819363A HUE032387T2 (hu) | 2006-10-27 | 2007-10-26 | Nagyon alacsony molekulatömegû polimereket tartalmazó nyújtott felszabadulású készítmények |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9724397B2 (hu) |
| EP (3) | EP1917971A1 (hu) |
| JP (2) | JP5410980B2 (hu) |
| CN (1) | CN101528249B (hu) |
| BR (1) | BRPI0718176B8 (hu) |
| CA (1) | CA2667424C (hu) |
| DK (1) | DK2086567T3 (hu) |
| ES (1) | ES2610400T3 (hu) |
| HU (1) | HUE032387T2 (hu) |
| MX (1) | MX2009004332A (hu) |
| PL (1) | PL2086567T3 (hu) |
| PT (1) | PT2086567T (hu) |
| RU (1) | RU2453329C2 (hu) |
| WO (1) | WO2008049631A1 (hu) |
Families Citing this family (16)
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|---|---|---|---|---|
| US9090737B2 (en) | 2007-11-13 | 2015-07-28 | Surmodics, Inc. | Viscous terpolymers as drug delivery platform |
| US8822546B2 (en) | 2008-12-01 | 2014-09-02 | Medtronic, Inc. | Flowable pharmaceutical depot |
| US8974808B2 (en) | 2008-12-23 | 2015-03-10 | Surmodics, Inc. | Elastic implantable composites and implants comprising same |
| US8951546B2 (en) | 2008-12-23 | 2015-02-10 | Surmodics Pharmaceuticals, Inc. | Flexible implantable composites and implants comprising same |
| US9415197B2 (en) | 2008-12-23 | 2016-08-16 | Surmodics, Inc. | Implantable suction cup composites and implants comprising same |
| US9480643B2 (en) | 2008-12-23 | 2016-11-01 | Surmodics Pharmaceuticals, Inc. | Implantable composites and implants comprising same |
| DE102009018013A1 (de) † | 2009-04-18 | 2010-10-21 | Qualimed Innovative Medizin-Produkte Gmbh | Beschichteter Stent |
| US9993441B2 (en) | 2009-12-30 | 2018-06-12 | Surmodics, Inc. | Controlled release matrix barrier structure for subcutaneous medical devices |
| WO2012030819A1 (en) | 2010-08-30 | 2012-03-08 | Surmodics Pharmaceuticals, Inc. | Terpolymers as pressure-sensitive adhesives |
| US20140107025A1 (en) * | 2012-04-16 | 2014-04-17 | Jade Therapeutics, Llc | Ocular drug delivery system |
| US10224258B2 (en) | 2013-03-22 | 2019-03-05 | Applied Materials, Inc. | Method of curing thermoplastics with microwave energy |
| CN104117056B (zh) * | 2013-04-28 | 2016-08-10 | 上海现代药物制剂工程研究中心有限公司 | 载胎盘生长因子纳米粒及其制备方法和应用 |
| AU2015254673B2 (en) | 2014-05-01 | 2019-01-17 | Ingell Technologies Holding B.V. | Liquid triblock copolymer |
| HUE046290T2 (hu) | 2016-09-13 | 2020-02-28 | Allergan Inc | Stabilizált, nem-fehérje clostridialis toxin készítmények |
| US20220354783A1 (en) | 2018-08-01 | 2022-11-10 | Edix-O Sarl | Injectable prolonged-action compositions for use in the treatment of nail disease and/or for promoting nail growth |
| EP3603650A1 (fr) | 2018-08-01 | 2020-02-05 | Edix O Sarl | Compositions injectables et a duree d'action prolongee pour leur utilisation dans le traitement de maladies de l'ongle et/ou pour accelerer la croissance de l'ongle |
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| SE353658B (hu) * | 1967-06-13 | 1973-02-12 | Dow Corning | |
| GB9211268D0 (en) * | 1992-05-28 | 1992-07-15 | Ici Plc | Salts of basic peptides with carboxyterminated polyesters |
| JP3524195B2 (ja) * | 1994-02-21 | 2004-05-10 | 武田薬品工業株式会社 | 徐放性製剤用基剤 |
| DE69508985T2 (de) * | 1994-02-21 | 1999-08-19 | Takeda Chemical Industries Ltd | Polyester Matrix für eine pharmazeutische Zusammensetzung mit verzögerter Freigabe |
| US5686110A (en) * | 1994-06-02 | 1997-11-11 | Enzon, Inc. | Water soluble complex of an alkyl or olefinic end capped polyalkylene oxide and a water insoluble substance |
| US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| EP0842209B1 (en) * | 1995-07-28 | 2006-10-11 | Genzyme Corporation | Multiblock biodegradable hydrogels for use as controlled release agents for drugs and tissue treatment agents |
| US6211249B1 (en) * | 1997-07-11 | 2001-04-03 | Life Medical Sciences, Inc. | Polyester polyether block copolymers |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| GB2354438A (en) * | 1999-09-23 | 2001-03-28 | Procter & Gamble | Polymer based compositions with anti-hydrolytic enzyme activity for use in pharmaceutical and cosmetic preparations |
| US20050042194A1 (en) * | 2000-05-11 | 2005-02-24 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| EP1392751B1 (en) * | 2001-05-07 | 2007-07-04 | Cornell Research Foundation, Inc. | Biodegradable copolymers linked to segment with a plurality of functional groups |
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| US20040137059A1 (en) * | 2003-01-09 | 2004-07-15 | Thierry Nivaggioli | Biodegradable ocular implant |
| US7309757B2 (en) * | 2003-06-20 | 2007-12-18 | Agency For Science, Technology And Research | Polymers for the delivery of bioactive agents and methods of their preparation |
| GB0412866D0 (en) * | 2004-06-09 | 2004-07-14 | Novartis Ag | Organic compounds |
| AU2005325213B2 (en) * | 2004-08-04 | 2010-10-07 | Evonik Corporation | Methods for manufacturing delivery devices and devices thereof |
| MX2007001760A (es) * | 2004-08-12 | 2007-07-24 | Quest Pharmaceutical Services | Composiciones farmaceuticas para la distribucion de liberacion controlada de compuestos biologicamente activos. |
| US8007775B2 (en) * | 2004-12-30 | 2011-08-30 | Advanced Cardiovascular Systems, Inc. | Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same |
| US20070196416A1 (en) * | 2006-01-18 | 2007-08-23 | Quest Pharmaceutical Services | Pharmaceutical compositions with enhanced stability |
| MX2008012683A (es) * | 2006-04-06 | 2009-01-07 | Nupathe Inc | Implantes para el tratamiento de estados asociados con dopamina. |
-
2006
- 2006-10-27 EP EP06291679A patent/EP1917971A1/en not_active Withdrawn
-
2007
- 2007-10-26 DK DK07819363.8T patent/DK2086567T3/en active
- 2007-10-26 EP EP16187114.0A patent/EP3141257A1/en not_active Withdrawn
- 2007-10-26 PL PL07819363T patent/PL2086567T3/pl unknown
- 2007-10-26 RU RU2009120005/15A patent/RU2453329C2/ru active
- 2007-10-26 MX MX2009004332A patent/MX2009004332A/es active IP Right Grant
- 2007-10-26 HU HUE07819363A patent/HUE032387T2/hu unknown
- 2007-10-26 BR BRPI0718176A patent/BRPI0718176B8/pt not_active IP Right Cessation
- 2007-10-26 JP JP2009533740A patent/JP5410980B2/ja not_active Expired - Fee Related
- 2007-10-26 WO PCT/EP2007/009318 patent/WO2008049631A1/en active Application Filing
- 2007-10-26 CN CN2007800400500A patent/CN101528249B/zh not_active Expired - Fee Related
- 2007-10-26 ES ES07819363.8T patent/ES2610400T3/es active Active
- 2007-10-26 EP EP07819363.8A patent/EP2086567B1/en active Active
- 2007-10-26 US US12/447,431 patent/US9724397B2/en active Active
- 2007-10-26 CA CA2667424A patent/CA2667424C/en not_active Expired - Fee Related
- 2007-10-26 PT PT78193638T patent/PT2086567T/pt unknown
-
2013
- 2013-10-30 JP JP2013225802A patent/JP5778741B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2667424C (en) | 2018-05-22 |
| CA2667424A1 (en) | 2008-05-02 |
| JP2014015488A (ja) | 2014-01-30 |
| EP2086567B1 (en) | 2016-10-19 |
| EP3141257A1 (en) | 2017-03-15 |
| CN101528249B (zh) | 2013-04-17 |
| WO2008049631A1 (en) | 2008-05-02 |
| US9724397B2 (en) | 2017-08-08 |
| US20100209384A1 (en) | 2010-08-19 |
| EP2086567A1 (en) | 2009-08-12 |
| MX2009004332A (es) | 2009-06-16 |
| RU2009120005A (ru) | 2010-12-10 |
| JP5778741B2 (ja) | 2015-09-16 |
| EP1917971A1 (en) | 2008-05-07 |
| DK2086567T3 (en) | 2017-01-23 |
| JP5410980B2 (ja) | 2014-02-05 |
| BRPI0718176B8 (pt) | 2021-05-25 |
| JP2010507612A (ja) | 2010-03-11 |
| PL2086567T3 (pl) | 2017-05-31 |
| RU2453329C2 (ru) | 2012-06-20 |
| BRPI0718176A2 (pt) | 2013-12-17 |
| ES2610400T3 (es) | 2017-04-27 |
| PT2086567T (pt) | 2017-01-17 |
| BRPI0718176B1 (pt) | 2018-06-05 |
| CN101528249A (zh) | 2009-09-09 |
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