PT2086567T - Formulações de libertação prolongada compreendendo polímeros de peso molecular muito baixo - Google Patents

Formulações de libertação prolongada compreendendo polímeros de peso molecular muito baixo

Info

Publication number
PT2086567T
PT2086567T PT78193638T PT07819363T PT2086567T PT 2086567 T PT2086567 T PT 2086567T PT 78193638 T PT78193638 T PT 78193638T PT 07819363 T PT07819363 T PT 07819363T PT 2086567 T PT2086567 T PT 2086567T
Authority
PT
Portugal
Prior art keywords
molecular weight
low molecular
sustained release
release formulations
weight polymers
Prior art date
Application number
PT78193638T
Other languages
English (en)
Inventor
Bourissou Didier
Cherif-Cheikh Roland
De Sousa Delgado Anne-Paula
Lacombe Frédéric
Original Assignee
Ipsen Pharma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas
Publication of PT2086567T publication Critical patent/PT2086567T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78193638T 2006-10-27 2007-10-26 Formulações de libertação prolongada compreendendo polímeros de peso molecular muito baixo PT2086567T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06291679A EP1917971A1 (en) 2006-10-27 2006-10-27 Substained release formulations comprising very low molecular weight polymers

Publications (1)

Publication Number Publication Date
PT2086567T true PT2086567T (pt) 2017-01-17

Family

ID=37907031

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78193638T PT2086567T (pt) 2006-10-27 2007-10-26 Formulações de libertação prolongada compreendendo polímeros de peso molecular muito baixo

Country Status (14)

Country Link
US (1) US9724397B2 (pt)
EP (3) EP1917971A1 (pt)
JP (2) JP5410980B2 (pt)
CN (1) CN101528249B (pt)
BR (1) BRPI0718176B8 (pt)
CA (1) CA2667424C (pt)
DK (1) DK2086567T3 (pt)
ES (1) ES2610400T3 (pt)
HU (1) HUE032387T2 (pt)
MX (1) MX2009004332A (pt)
PL (1) PL2086567T3 (pt)
PT (1) PT2086567T (pt)
RU (1) RU2453329C2 (pt)
WO (1) WO2008049631A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009064442A1 (en) 2007-11-13 2009-05-22 Brookwood Pharmaceuticals, Inc. Viscous terpolymers as drug delivery platform
US8822546B2 (en) 2008-12-01 2014-09-02 Medtronic, Inc. Flowable pharmaceutical depot
US9480643B2 (en) 2008-12-23 2016-11-01 Surmodics Pharmaceuticals, Inc. Implantable composites and implants comprising same
US9415197B2 (en) 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
US8974808B2 (en) 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US8951546B2 (en) 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
DE102009018013A1 (de) † 2009-04-18 2010-10-21 Qualimed Innovative Medizin-Produkte Gmbh Beschichteter Stent
US9993441B2 (en) 2009-12-30 2018-06-12 Surmodics, Inc. Controlled release matrix barrier structure for subcutaneous medical devices
WO2012030821A1 (en) 2010-08-30 2012-03-08 Surmodics Pharmaceuticals, Inc. Terpolymer blends and their use as pressure-sensitive adhesives
US20140107025A1 (en) * 2012-04-16 2014-04-17 Jade Therapeutics, Llc Ocular drug delivery system
US10224258B2 (en) 2013-03-22 2019-03-05 Applied Materials, Inc. Method of curing thermoplastics with microwave energy
CN104117056B (zh) * 2013-04-28 2016-08-10 上海现代药物制剂工程研究中心有限公司 载胎盘生长因子纳米粒及其制备方法和应用
DK3137532T3 (da) 2014-05-01 2021-08-02 Ingell Tech Holding B V Flydende triblok-copolymer
IL308091B1 (en) 2016-09-13 2026-01-01 Allergan Inc Protein-free stabilized Clostridium toxin preparations
EP3829601B1 (fr) 2018-08-01 2024-05-29 Edix-O Sarl Compositions injectables à durée d'action prolongée pour leur utilisation dans le traitement de maladies de l'ongle
EP3603650A1 (fr) 2018-08-01 2020-02-05 Edix O Sarl Compositions injectables et a duree d'action prolongee pour leur utilisation dans le traitement de maladies de l'ongle et/ou pour accelerer la croissance de l'ongle

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE353658B (pt) * 1967-06-13 1973-02-12 Dow Corning
GB9211268D0 (en) * 1992-05-28 1992-07-15 Ici Plc Salts of basic peptides with carboxyterminated polyesters
US5594091A (en) * 1994-02-21 1997-01-14 Takeda Chemical Industries, Ltd. Matrix for sustained-release preparation
JP3524195B2 (ja) * 1994-02-21 2004-05-10 武田薬品工業株式会社 徐放性製剤用基剤
US5686110A (en) * 1994-06-02 1997-11-11 Enzon, Inc. Water soluble complex of an alkyl or olefinic end capped polyalkylene oxide and a water insoluble substance
US5595760A (en) 1994-09-02 1997-01-21 Delab Sustained release of peptides from pharmaceutical compositions
WO1997005185A2 (en) * 1995-07-28 1997-02-13 Focal, Inc. Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatment agents
US6211249B1 (en) * 1997-07-11 2001-04-03 Life Medical Sciences, Inc. Polyester polyether block copolymers
US6143314A (en) 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
US6565874B1 (en) * 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
GB2354438A (en) * 1999-09-23 2001-03-28 Procter & Gamble Polymer based compositions with anti-hydrolytic enzyme activity for use in pharmaceutical and cosmetic preparations
US20050042194A1 (en) * 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
CA2440394C (en) * 2001-05-07 2011-10-04 Cornell Research Foundation, Inc. Biodegradable copolymers linked to segment with a plurality of functional groups
WO2003051328A1 (en) * 2001-12-18 2003-06-26 Novo Nordisk A/S Solid dose micro implant
US20040001889A1 (en) * 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
CA2494342A1 (en) 2002-07-31 2004-02-12 Alza Corporation Injectable depot compositions and uses thereof
US20040137059A1 (en) 2003-01-09 2004-07-15 Thierry Nivaggioli Biodegradable ocular implant
US7309757B2 (en) * 2003-06-20 2007-12-18 Agency For Science, Technology And Research Polymers for the delivery of bioactive agents and methods of their preparation
GB0412866D0 (en) * 2004-06-09 2004-07-14 Novartis Ag Organic compounds
EP1781264B1 (en) * 2004-08-04 2013-07-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
KR101231856B1 (ko) * 2004-08-12 2013-02-08 큐피에스 엘엘씨 생물학적 활성 화합물의 제어 방출 전달용 약학 조성물
US8007775B2 (en) * 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
MX2008009125A (es) * 2006-01-18 2008-10-23 Qps Llc Composiciones farmaceuticas con estabilidad mejorada.
US8475829B2 (en) * 2006-04-06 2013-07-02 Nupathe Inc. Implants for the treatment of dopamine associated states

Also Published As

Publication number Publication date
EP2086567A1 (en) 2009-08-12
WO2008049631A1 (en) 2008-05-02
CA2667424C (en) 2018-05-22
PL2086567T3 (pl) 2017-05-31
BRPI0718176B8 (pt) 2021-05-25
HUE032387T2 (en) 2017-09-28
US9724397B2 (en) 2017-08-08
DK2086567T3 (en) 2017-01-23
RU2453329C2 (ru) 2012-06-20
EP3141257A1 (en) 2017-03-15
BRPI0718176A2 (pt) 2013-12-17
JP5410980B2 (ja) 2014-02-05
BRPI0718176B1 (pt) 2018-06-05
EP2086567B1 (en) 2016-10-19
JP5778741B2 (ja) 2015-09-16
CA2667424A1 (en) 2008-05-02
RU2009120005A (ru) 2010-12-10
US20100209384A1 (en) 2010-08-19
ES2610400T3 (es) 2017-04-27
CN101528249A (zh) 2009-09-09
CN101528249B (zh) 2013-04-17
JP2010507612A (ja) 2010-03-11
MX2009004332A (es) 2009-06-16
EP1917971A1 (en) 2008-05-07
JP2014015488A (ja) 2014-01-30

Similar Documents

Publication Publication Date Title
PL2086567T3 (pl) Formulacje o przedłużonym uwalnianiu zawierające polimery o bardzo niskim ciężarze cząsteczkowym
IL198168A0 (en) Robust sustained release formulations
EP2046885A4 (en) FORMABLE BIODEGRADABLE POLYMER
IL184460A0 (en) Sustained release pharmaeutical formulations
ZA200808637B (en) Polymers
IL182405A0 (en) Mouldable biodegradable polymer
IL188964A0 (en) Sustained drug release composition
IL193416A0 (en) Improved preparation of molecular imprinted polymers
AP2941A (en) Self-assembling amphiphilic polymers as anticanceragents
EP2049591A4 (en) BIOKOMPATIBLE POLYMERIC COMPOSITIONS
EP2119442A4 (en) PHARMACEUTICAL COMPOSITION WITH TACROLIMUS MAINTAINED RELEASE
AP2523A (en) Self-assembling amphiphilic polymers as antiviral agents
IL178596A0 (en) Sustained release formulations
EP2297218A4 (en) AMPHIPHILIC SEQUENCED COPOLYMER FORMULATIONS
GB2456407B (en) Polymer compositions
EP2001442A4 (en) NOVEL EXPERIMENTAL FORMULATIONS WITH HYDROCOLLOIDAL POLYMERS
GB0525970D0 (en) Supramolecular polymers
ZA200807219B (en) Improved preparation of molecular imprinted polymers
IL178793A0 (en) Low molecular weight polylactic acid polymers
GB0604911D0 (en) Polymers
EP1871348A4 (en) PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE
IL187507A0 (en) Propylene polymers having broad molecular weight distribution
GB0511841D0 (en) Polymer formulations
ZA200804629B (en) Sustained release formulation comprising octreotide and two or more polyactide-co-glycolide polymers
ZA200902096B (en) Robust sustained release formulations