HU9302820D0 - Process for separation of biomolecules with application of linear polymers - Google Patents
Process for separation of biomolecules with application of linear polymersInfo
- Publication number
- HU9302820D0 HU9302820D0 HU9302820A HU9302820A HU9302820D0 HU 9302820 D0 HU9302820 D0 HU 9302820D0 HU 9302820 A HU9302820 A HU 9302820A HU 9302820 A HU9302820 A HU 9302820A HU 9302820 D0 HU9302820 D0 HU 9302820D0
- Authority
- HU
- Hungary
- Prior art keywords
- biomolecules
- separation
- application
- linear polymers
- polymers
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/817,610 US5525519A (en) | 1992-01-07 | 1992-01-07 | Method for isolating biomolecules from a biological sample with linear polymers |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9302820D0 true HU9302820D0 (en) | 1993-12-28 |
HUT65139A HUT65139A (en) | 1994-04-28 |
Family
ID=25223460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9302820A HUT65139A (en) | 1992-01-07 | 1993-01-07 | Process for separating biomolecules by using linear polymers |
Country Status (7)
Country | Link |
---|---|
US (2) | US5525519A (hu) |
EP (1) | EP0574575A1 (hu) |
JP (2) | JPH06503366A (hu) |
AU (1) | AU667508B2 (hu) |
CA (1) | CA2104772A1 (hu) |
HU (1) | HUT65139A (hu) |
WO (1) | WO1993014110A1 (hu) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525519A (en) * | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
US5554730A (en) * | 1993-03-09 | 1996-09-10 | Middlesex Sciences, Inc. | Method and kit for making a polysaccharide-protein conjugate |
DE69408527T2 (de) * | 1993-03-09 | 1998-06-04 | Epic Therapeutics Inc | Makromolekulare mikropartikel und verfahren zu ihrer herstellung |
US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
WO1996020012A2 (en) * | 1994-12-23 | 1996-07-04 | Middlesex Sciences, Inc. | Methods for preparing and purifying macromolecular conjugates |
GB9810799D0 (en) * | 1998-05-21 | 1998-07-15 | Boots Co Plc | Antimicrobial agent |
US6231889B1 (en) * | 1998-09-21 | 2001-05-15 | Chronorx, Llc | Unit dosage forms for the treatment of herpes simplex |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
EP2280004B1 (en) | 1999-06-29 | 2016-04-20 | MannKind Corporation | Pharmaceutical formulations comprising insulin complexed with a diketopiperazine |
US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
US7374782B2 (en) | 2000-10-27 | 2008-05-20 | Baxter International Inc. | Production of microspheres |
US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
US20030064033A1 (en) * | 2001-08-16 | 2003-04-03 | Brown Larry R. | Propellant-based microparticle formulations |
WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
US7459154B2 (en) * | 2002-12-26 | 2008-12-02 | Cell Genesys, Inc. | Methods and reagents for the enhancement of virus transduction in the bladder epithelium |
WO2005035088A2 (en) * | 2003-07-18 | 2005-04-21 | Baxter International, Inc. | Method for preparing small spherical by controlled phase separation |
US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
CA2532874A1 (en) * | 2003-07-22 | 2005-02-03 | Baxter International Inc. | Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof |
US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
ES2442115T3 (es) * | 2004-05-12 | 2014-02-10 | Baxter International Inc. | Microesferas que contienen oligonucleótidos, su utilización para la preparación de un medicamento para el tratamiento de la diabetes tipo 1 |
WO2005112893A1 (en) | 2004-05-12 | 2005-12-01 | Baxter International Inc. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
EP2072040B1 (en) | 2004-05-12 | 2013-05-01 | Baxter International Inc. | Therapeutic use of nucleic acid micropheres |
US8410246B2 (en) | 2004-06-17 | 2013-04-02 | Thrasos, Inc. | TDF-related compounds and analogs thereof |
JP5078014B2 (ja) | 2004-08-20 | 2012-11-21 | マンカインド コーポレイション | ジケトピペラジン合成の触媒反応 |
MX2007002189A (es) | 2004-08-23 | 2008-01-11 | Mannkind Corp | Sales de dicetopiperazina, sales de dicetomorfolina o sales de dicetodioxano para suministro de farmacos. |
CA2604225A1 (en) * | 2005-04-27 | 2006-11-02 | Baxter International Inc. | Surface-modified microparticles and methods of forming and using the same |
US7803404B2 (en) | 2005-09-14 | 2010-09-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
SI2497780T1 (sl) | 2005-09-20 | 2015-08-31 | Thrasos Innovation, Inc. | Spojine, povezane s TDF, in njihovi analogi |
IN2015DN00888A (hu) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
US7964574B2 (en) * | 2006-08-04 | 2011-06-21 | Baxter International Inc. | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
MX2009003661A (es) * | 2006-10-06 | 2009-04-22 | Baxter Int | Microcapsulas que contienen microparticulas modificadas en la superficie y metodos para formar y utilizar las mismas. |
US8569464B2 (en) * | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
US8163886B2 (en) * | 2006-12-21 | 2012-04-24 | Emd Millipore Corporation | Purification of proteins |
AU2008209404B2 (en) * | 2007-01-22 | 2012-08-16 | Genentech, Inc. | Polyelectrolyte precipitation and purification of antibodies |
US8086409B2 (en) * | 2007-01-30 | 2011-12-27 | The Trustees Of Columbia University In The City Of New York | Method of selecting genes from continuous gene expression data based on synergistic interactions among genes |
AU2008214319A1 (en) * | 2007-02-06 | 2008-08-14 | Incept, Llc | Polymerization with precipitation of proteins for elution in physiological solution |
US8808747B2 (en) * | 2007-04-17 | 2014-08-19 | Baxter International Inc. | Nucleic acid microparticles for pulmonary delivery |
CA2720048A1 (en) * | 2008-04-16 | 2009-10-22 | Biogen Idec Ma Inc. | Method of isolating biomacromolecules using polyalkylene glycol and transition metals |
ES2554168T3 (es) | 2008-04-18 | 2015-12-16 | Baxter International Inc. | Composición basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nueva aparición |
WO2009151514A1 (en) * | 2008-06-11 | 2009-12-17 | Millipore Corporation | Stirred tank bioreactor |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101933816B1 (ko) | 2008-06-13 | 2019-03-29 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
WO2009155581A1 (en) | 2008-06-20 | 2009-12-23 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8367427B2 (en) * | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
WO2010074953A1 (en) | 2008-12-16 | 2010-07-01 | Millipore Corporation | Stirred tank reactor and method |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
BRPI1013154B1 (pt) | 2009-06-12 | 2020-04-07 | Mannkind Corp | Micropartículas de dicetopiperazina com áreas de superfície específicas definidas, pó seco compreendendo as referidas micropartículas, método para formação das referidasmicropartículas e formação de micropartículas de fumaril diacetopiperazina, uso das referidas micropartículas e sistema de inalação |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
US8691918B2 (en) | 2010-05-17 | 2014-04-08 | Emd Millipore Corporation | Stimulus responsive polymers for the purification of biomolecules |
MX359281B (es) | 2010-06-21 | 2018-09-21 | Mannkind Corp | Sistema y metodos para suministrar un farmaco en polvo seco. |
MX353285B (es) | 2011-04-01 | 2018-01-05 | Mannkind Corp | Paquete de blister para cartuchos farmaceuticos. |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
IN2014DN03093A (hu) | 2011-10-24 | 2015-05-15 | Mannkind Corp | |
WO2013114373A1 (en) | 2012-02-01 | 2013-08-08 | Protalix Ltd. | Inhalable liquid formulations of dnase i |
SG10201605800UA (en) | 2012-07-12 | 2016-09-29 | Mannkind Corp | Dry powder drug delivery system and methods |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
WO2014097289A1 (en) * | 2012-12-20 | 2014-06-26 | Omrix Biopharmaceuticals Ltd. | Viral inactivated biological mixture |
KR102499439B1 (ko) | 2013-03-15 | 2023-02-13 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
CA2918369C (en) | 2013-07-18 | 2021-06-29 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
KR102356757B1 (ko) * | 2013-10-18 | 2022-02-03 | 노바셉 이큅먼트 솔루션즈 | 단백질 정제 |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
US20170304459A1 (en) | 2014-10-10 | 2017-10-26 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for inhalation delivery of conjugated oligonucleotide |
JP6583766B2 (ja) * | 2015-02-02 | 2019-10-02 | 学校法人北里研究所 | タンパク質分離方法、タンパク質分析方法、及びタンパク質分離キット |
US10426796B2 (en) | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
EP4138884A1 (en) | 2020-04-20 | 2023-03-01 | Sorrento Therapeutics, Inc. | Pulmonary administration of ace2 polypeptides |
CN115521895B (zh) * | 2021-06-24 | 2024-04-05 | 上海思路迪生物医学科技有限公司 | 水溶性蛋白作为外泌体提取增强剂的应用及外泌体提取试剂 |
EP4163369A1 (en) | 2021-10-08 | 2023-04-12 | AXAGARIUS GmbH & Co. KG | Use of mixtures of polyvinylpyrrolidone and ammonium sulfate in the isolation of nucleic acids |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3652530A (en) * | 1967-08-28 | 1972-03-28 | American Nat Red Cross | Antihemophilic factor prepared from blood plasma using polyethylene glycol |
US3897414A (en) * | 1969-09-12 | 1975-07-29 | Pharmacia Fine Chemicals Ab | Method of fractionating a mixture of high molecular substances of different physical characteristics |
US3631018A (en) * | 1970-05-01 | 1971-12-28 | Baxter Laboratories Inc | Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate |
US3869436A (en) * | 1971-06-01 | 1975-03-04 | Statens Bakteriologiska Lab | Method for fractionating plasma proteins using peg and ion-exchangers |
US3790552A (en) * | 1972-03-16 | 1974-02-05 | Us Health | Method of removing hepatitis-associated antigen from a protein fraction using polyethylene glycol |
CA1064396A (en) * | 1975-02-18 | 1979-10-16 | Myer L. Coval | Fractional precipitation of gamma globulin with polyethylene glycol |
DE2512735A1 (de) * | 1975-03-22 | 1976-09-30 | Henkel & Cie Gmbh | Verfahren zur gewinnung von proteinen aus waessrigen protein- loesungen |
US4164495A (en) * | 1976-04-06 | 1979-08-14 | Nordisk Insulinlaboratorium | Method of recovering immunoglobulin using a polyol and an alkanoic acid |
DK139056B (da) * | 1976-04-06 | 1978-12-11 | Nordisk Insulinlab | Fremgangsmåde til udvinding af immunoglobulin, der er egnet til intravenøs indgivelse. |
US4165370A (en) * | 1976-05-21 | 1979-08-21 | Coval M L | Injectable gamma globulin |
DK144731C (da) * | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev |
US4124576A (en) * | 1976-12-03 | 1978-11-07 | Coval M L | Method of producing intravenously injectable gamma globulin |
DK25877A (da) * | 1977-01-21 | 1978-08-15 | Nordisk Insulinlab | Fremgangsmaade til udvinding af renset albumin fra blodplasma |
JPS53127808A (en) * | 1977-04-12 | 1978-11-08 | Green Cross Corp:The | Preparation of human albumin |
JPS5843369B2 (ja) * | 1977-09-10 | 1983-09-27 | 森六株式会社 | 血清蛋白質の分画方法 |
SU1109170A1 (ru) * | 1982-03-30 | 1984-08-23 | Московский научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова | Способ получени иммуноглобулина |
JPS59157017A (ja) * | 1983-02-25 | 1984-09-06 | Green Cross Corp:The | 静脈投与用γ−グロブリン製剤 |
JPS6042336A (ja) * | 1983-08-18 | 1985-03-06 | Nippon Seiyaku Kk | 免疫グロブリンの製造方法 |
GB8403473D0 (en) * | 1984-02-09 | 1984-03-14 | Special Trustees For St Thomas | Purification of factor viii |
US4543210A (en) * | 1984-10-04 | 1985-09-24 | Miles Laboratories, Inc. | Process for producing a high purity antihemophilic factor concentrate |
DE3509892C2 (de) * | 1985-03-19 | 1994-04-21 | Westfalia Separator Ag | Verfahren zum Nachklären und Stabilisieren von Polyphenole und/oder Eiweißstoffe enthaltenden Flüssigkeiten und Getränken, insbesondere von Bier |
US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
FR2582515B1 (fr) * | 1985-05-30 | 1988-11-04 | Merieux Inst | Procede de preparation de gamma-gobulines administrables par voie intraveineuse et gamma-globulines obtenues |
SE459005B (sv) * | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
SE462100B (sv) * | 1985-08-08 | 1990-05-07 | Perstorp Ab | Komposition och dess anvaendning i ett tvaa- eller flerfassystem |
AU591964B2 (en) * | 1986-01-06 | 1989-12-21 | University Of Melbourne, The | Collagen products |
DE3606382A1 (de) * | 1986-02-27 | 1987-09-03 | Henkel Kgaa | Verbesserter klebestift |
GB8822857D0 (en) * | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
PH26730A (en) * | 1988-12-30 | 1992-09-28 | Ciba Geigy Ag | Coated adhesive tablets |
US5177194A (en) * | 1990-02-01 | 1993-01-05 | Baxter International, Inc. | Process for purifying immune serum globulins |
US5135875A (en) * | 1990-08-15 | 1992-08-04 | Abbott Laboratories | Protein precipitation reagent |
US5525519A (en) * | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
US5288853A (en) * | 1992-04-30 | 1994-02-22 | Alpha Therapeutic Corporation | Factor viii purification process |
-
1992
- 1992-01-07 US US07/817,610 patent/US5525519A/en not_active Expired - Lifetime
-
1993
- 1993-01-07 HU HU9302820A patent/HUT65139A/hu unknown
- 1993-01-07 EP EP93902952A patent/EP0574575A1/en not_active Withdrawn
- 1993-01-07 AU AU34344/93A patent/AU667508B2/en not_active Ceased
- 1993-01-07 US US08/107,822 patent/US5599719A/en not_active Expired - Lifetime
- 1993-01-07 WO PCT/US1993/000073 patent/WO1993014110A1/en not_active Application Discontinuation
- 1993-01-07 JP JP5512538A patent/JPH06503366A/ja active Pending
- 1993-01-07 CA CA002104772A patent/CA2104772A1/en not_active Abandoned
-
1996
- 1996-05-30 JP JP8137121A patent/JPH09157288A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH06503366A (ja) | 1994-04-14 |
EP0574575A1 (en) | 1993-12-22 |
US5599719A (en) | 1997-02-04 |
JPH09157288A (ja) | 1997-06-17 |
US5525519A (en) | 1996-06-11 |
HUT65139A (en) | 1994-04-28 |
AU3434493A (en) | 1993-08-03 |
CA2104772A1 (en) | 1993-07-08 |
WO1993014110A1 (en) | 1993-07-22 |
AU667508B2 (en) | 1996-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU9302820D0 (en) | Process for separation of biomolecules with application of linear polymers | |
ZA905308B (en) | Process for the preparation of cycloolefin polymers | |
AP9300537A0 (en) | Novel process | |
GB9204064D0 (en) | Method of identifying polymer materials | |
GB9209687D0 (en) | Novel process | |
ZA933521B (en) | Process for the separation of cobalt | |
HUT64763A (en) | Process for the production of cyclobutane-purines | |
GB9221527D0 (en) | Moulding process | |
IL108015A0 (en) | Process for the production of polypeptides | |
EP0405467A3 (en) | A process for the determination of interleukins | |
EP0435042A3 (en) | Method for thermoplastics postforming | |
LTIP217A (en) | Process for the polymerisation of epoxycompounds | |
ZA9410171B (en) | Process for the preparation of polyolefins | |
GB9214116D0 (en) | Separation process | |
GB9211730D0 (en) | Separation process | |
GB9210709D0 (en) | Separation process | |
GB9208793D0 (en) | Separation process | |
GB9203710D0 (en) | Separation process | |
GB8907642D0 (en) | Process for purification of biomolecules | |
GB9215494D0 (en) | Process for the conversion of polymers | |
GB9213772D0 (en) | Process for the conversion of polymers | |
GB9201855D0 (en) | Enhanced separation process | |
IL92698A0 (en) | Process for the separation of gases | |
PL282161A1 (en) | Method of stabilizing the polyethylene thermooxidizing process | |
IL96857A0 (en) | Process for the separation of gases |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFD9 | Temporary protection cancelled due to non-payment of fee |