HU217124B - Eljárás (S)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamid-tartalmú, szorongás oldására alkalmas gyógyászati készítmények előállítására - Google Patents

Eljárás (S)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamid-tartalmú, szorongás oldására alkalmas gyógyászati készítmények előállítására Download PDF

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Publication number
HU217124B
HU217124B HU9402704A HU9402704A HU217124B HU 217124 B HU217124 B HU 217124B HU 9402704 A HU9402704 A HU 9402704A HU 9402704 A HU9402704 A HU 9402704A HU 217124 B HU217124 B HU 217124B
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HU
Hungary
Prior art keywords
anxiety
animals
oxo
compound
formula
Prior art date
Application number
HU9402704A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT68299A (en
Inventor
Eric Cossement
Jean Gobert
Alma Gower
Ernst Wülfert
Original Assignee
Ucb S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb S.A. filed Critical Ucb S.A.
Publication of HUT68299A publication Critical patent/HUT68299A/hu
Publication of HU217124B publication Critical patent/HU217124B/hu

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
HU9402704A 1993-09-24 1994-09-20 Eljárás (S)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamid-tartalmú, szorongás oldására alkalmas gyógyászati készítmények előállítására HU217124B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939319732A GB9319732D0 (en) 1993-09-24 1993-09-24 Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety

Publications (2)

Publication Number Publication Date
HUT68299A HUT68299A (en) 1995-06-28
HU217124B true HU217124B (hu) 1999-11-29

Family

ID=10742476

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9402704A HU217124B (hu) 1993-09-24 1994-09-20 Eljárás (S)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamid-tartalmú, szorongás oldására alkalmas gyógyászati készítmények előállítására

Country Status (17)

Country Link
US (1) US5447952A (OSRAM)
EP (1) EP0645139B1 (OSRAM)
JP (1) JP3688735B2 (OSRAM)
KR (1) KR950007848A (OSRAM)
AT (1) ATE191849T1 (OSRAM)
AU (1) AU672334B2 (OSRAM)
CA (1) CA2132509A1 (OSRAM)
DE (1) DE69424009T2 (OSRAM)
ES (1) ES2145818T3 (OSRAM)
GB (1) GB9319732D0 (OSRAM)
HU (1) HU217124B (OSRAM)
NO (1) NO943521L (OSRAM)
NZ (1) NZ264506A (OSRAM)
RU (1) RU2142274C1 (OSRAM)
SG (1) SG86284A1 (OSRAM)
TW (1) TW283642B (OSRAM)
ZA (1) ZA947444B (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525347A (en) * 1995-01-31 1996-06-11 Medical University Of South Carolina Composition and methods for treating performance anxiety
IL149530A0 (en) 1999-12-01 2002-11-10 Ucb Sa A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
PT1810676E (pt) * 2006-01-24 2009-01-02 Teva Pharma Formulações de levetiracetam e métodos para a sua preparação
KR101065239B1 (ko) * 2006-03-15 2011-09-16 액테리온 파마슈티칼 리미티드 기억 기능을 증진하는 테트라히드로이소퀴놀린 유도체
EP2051696A2 (en) * 2006-08-18 2009-04-29 Morton Grove Pharmaceuticals, Inc. Stable liquid levetiracetam compositions and methods
ATE524466T1 (de) * 2007-07-03 2011-09-15 Actelion Pharmaceuticals Ltd 3-azabicycloä3.3.0üoktanverbindungen
WO2009016564A2 (en) * 2007-07-27 2009-02-05 Actelion Pharmaceuticals Ltd 2-aza-bicyclo[3.3.0]octane derivatives
EA033130B1 (ru) 2008-10-16 2019-08-30 Дзе Джонс Хопкинс Юниверсити Способы и композиции для улучшения когнитивной функции
US8191547B2 (en) * 2008-10-23 2012-06-05 S-2Tech Llc Portable solar-heating system having an inflatable solar collector
US20100172979A1 (en) * 2008-12-24 2010-07-08 Zhongshui Yu Controlled-release formulations
US20100159009A1 (en) * 2008-12-24 2010-06-24 Zhongshui Yu Controlled-release formulations
WO2011100373A1 (en) * 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
AU2012214303A1 (en) * 2011-02-09 2013-09-12 The Johns Hopkins University Methods and compositions for improving cognitive function
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
HK1218623A1 (zh) 2013-03-15 2017-03-03 艾吉因生物股份有限公司 用於改善認知功能的方法和組合物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN112843005B (zh) 2015-05-22 2023-02-21 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物
CA3117350A1 (en) * 2018-12-04 2020-06-11 Metys Pharmaceuticals AG Synergistic compositions comprising (r)-2-(2-oxopyrrolidin-1-yl)butanamide and (s)-2-(2-oxopyrrolidin-1-yl)butanamide in a non-racemic ratio

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1414845A1 (ru) * 1984-03-23 1988-08-07 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени
GB8412357D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
SU1320707A1 (ru) * 1985-01-24 1987-06-30 Ивано-Франковский Институт Нефти И Газа Способ определени износостойкости материалов ма тниковым склерометром
GB8827389D0 (en) 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide
EP0408782A1 (en) * 1989-07-18 1991-01-23 Nauchnoissledovatelski Chimikopharmatzevtichen Institut Antihypoxic agent
CA2048003A1 (en) * 1990-08-21 1992-02-22 Serge Burner Tricyclic pyridone derivatives

Also Published As

Publication number Publication date
NO943521L (no) 1995-03-27
ZA947444B (en) 1995-05-11
JPH07149639A (ja) 1995-06-13
TW283642B (OSRAM) 1996-08-21
AU672334B2 (en) 1996-09-26
AU7416994A (en) 1995-04-06
RU2142274C1 (ru) 1999-12-10
EP0645139B1 (fr) 2000-04-19
ATE191849T1 (de) 2000-05-15
NZ264506A (en) 1997-09-22
ES2145818T3 (es) 2000-07-16
DE69424009T2 (de) 2000-09-14
KR950007848A (ko) 1995-04-15
CA2132509A1 (en) 1995-03-25
EP0645139A1 (fr) 1995-03-29
HUT68299A (en) 1995-06-28
JP3688735B2 (ja) 2005-08-31
NO943521D0 (no) 1994-09-22
GB9319732D0 (en) 1993-11-10
DE69424009D1 (de) 2000-05-25
US5447952A (en) 1995-09-05
SG86284A1 (en) 2002-02-19

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