HU215587B - Eljárás alfa- és béta-interferonokkal szemben nagy affinitással rendelkező vízoldható polipeptidek, az azokat kódoló DNS-szekvenciák, a polipeptideket kifejezni képes sejtek és a polipeptideket tartalmazó gyógyászati készítmények előállítására - Google Patents
Eljárás alfa- és béta-interferonokkal szemben nagy affinitással rendelkező vízoldható polipeptidek, az azokat kódoló DNS-szekvenciák, a polipeptideket kifejezni képes sejtek és a polipeptideket tartalmazó gyógyászati készítmények előállítására Download PDFInfo
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- HU215587B HU215587B HU9203955A HU395592A HU215587B HU 215587 B HU215587 B HU 215587B HU 9203955 A HU9203955 A HU 9203955A HU 395592 A HU395592 A HU 395592A HU 215587 B HU215587 B HU 215587B
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- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 238000010490 three component reaction Methods 0.000 description 1
- 125000000341 threoninyl group Chemical group [H]OC([H])(C([H])([H])[H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000003151 transfection method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 101150108727 trpl gene Proteins 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 231100000925 very toxic Toxicity 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9001298A FR2657881A1 (fr) | 1990-02-05 | 1990-02-05 | Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9203955D0 HU9203955D0 (en) | 1993-03-29 |
| HUT65413A HUT65413A (en) | 1994-06-28 |
| HU215587B true HU215587B (hu) | 1999-01-28 |
Family
ID=9393388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9203955A HU215587B (hu) | 1990-02-05 | 1991-04-17 | Eljárás alfa- és béta-interferonokkal szemben nagy affinitással rendelkező vízoldható polipeptidek, az azokat kódoló DNS-szekvenciák, a polipeptideket kifejezni képes sejtek és a polipeptideket tartalmazó gyógyászati készítmények előállítására |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR2657881A1 (enrdf_load_stackoverflow) |
| HU (1) | HU215587B (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2133285T3 (es) | 1991-04-17 | 1999-09-16 | Medisup Int Nv | Polipeptidos hidrosolubles que tienen una alta afinidad para los interferones alfa y beta. |
| US6429186B1 (en) | 1991-05-10 | 2002-08-06 | Genentech, Inc. | Ligand antagonists for treatment of breast cancer |
| EP0563487A1 (en) | 1992-03-31 | 1993-10-06 | Laboratoire Europeen De Biotechnologie S.A. | Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon |
| IL106591A (en) * | 1992-09-03 | 2008-03-20 | Yeda Res & Dev | Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it |
| US5821078A (en) * | 1992-09-03 | 1998-10-13 | Yeda Research And Development Co. Ltd. | Nucleic acid encoding interferon-α/β binding protein |
| US7087726B2 (en) | 2001-02-22 | 2006-08-08 | Genentech, Inc. | Anti-interferon-α antibodies |
-
1990
- 1990-02-05 FR FR9001298A patent/FR2657881A1/fr active Granted
-
1991
- 1991-04-17 HU HU9203955A patent/HU215587B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HU9203955D0 (en) | 1993-03-29 |
| FR2657881B1 (enrdf_load_stackoverflow) | 1994-08-19 |
| HUT65413A (en) | 1994-06-28 |
| FR2657881A1 (fr) | 1991-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DNF4 | Restoration of lapsed final protection | ||
| HPC4 | Succession in title of patentee |
Owner name: MEDISUP INTERNATIONAL N.V., ING TRUST (ANTILLES) N |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |