HU179967B - Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives - Google Patents

Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives Download PDF

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Publication number
HU179967B
HU179967B HU78EI784A HUEI000784A HU179967B HU 179967 B HU179967 B HU 179967B HU 78EI784 A HU78EI784 A HU 78EI784A HU EI000784 A HUEI000784 A HU EI000784A HU 179967 B HU179967 B HU 179967B
Authority
HU
Hungary
Prior art keywords
methyl
formula
compound
reaction
acetamido
Prior art date
Application number
HU78EI784A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Lowell D Hatfield
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/862,871 external-priority patent/US4144391A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU179967B publication Critical patent/HU179967B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU78EI784A 1977-03-07 1978-03-03 Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives HU179967B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77501877A 1977-03-07 1977-03-07
US05/862,871 US4144391A (en) 1977-03-07 1977-12-27 Cephalosporin displacement reaction

Publications (1)

Publication Number Publication Date
HU179967B true HU179967B (en) 1983-01-28

Family

ID=27118982

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78EI784A HU179967B (en) 1977-03-07 1978-03-03 Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives

Country Status (30)

Country Link
JP (1) JPS53130689A (fr)
AT (1) AT366696B (fr)
AU (1) AU515428B2 (fr)
BG (1) BG31379A3 (fr)
CA (1) CA1083141A (fr)
CH (1) CH637964A5 (fr)
CS (1) CS205115B2 (fr)
CY (1) CY1196A (fr)
DD (1) DD137356A5 (fr)
DE (1) DE2809058A1 (fr)
DK (1) DK97378A (fr)
EG (1) EG13454A (fr)
ES (1) ES467637A1 (fr)
FI (1) FI69309C (fr)
FR (1) FR2383189A1 (fr)
GB (1) GB1597036A (fr)
GR (1) GR68893B (fr)
HK (1) HK49083A (fr)
HU (1) HU179967B (fr)
IE (1) IE46437B1 (fr)
IL (1) IL54181A (fr)
IT (1) IT1093504B (fr)
MX (1) MX5142E (fr)
NL (1) NL190703C (fr)
NZ (1) NZ186610A (fr)
PH (1) PH14596A (fr)
PL (1) PL122152B1 (fr)
PT (1) PT67732A (fr)
SE (1) SE437991B (fr)
YU (1) YU51478A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
JP2503500B2 (ja) * 1986-04-14 1996-06-05 萬有製薬株式会社 新規セフアロスポリン誘導体及びその製造法
JPS62281881A (ja) * 1986-09-08 1987-12-07 Sankyo Co Ltd ３−置換チオメチルセフアロスポリン誘導体の製法
US20120329770A1 (en) * 2010-02-26 2012-12-27 Gary Igor Dmitrienko Cephalosporin derivatives useful as beta-lactamase inhibitors and compositions and methods of use thereof
GB201818410D0 (en) * 2018-11-12 2018-12-26 Imperial Innovations Ltd Compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
JPS5116436B1 (fr) * 1971-05-31 1976-05-24
JPS5143785A (en) * 1974-10-11 1976-04-14 Yamanouchi Pharma Co Ltd Shinsefuarosuhorinkanrenkagobutsuno goseiho
JPS612674B2 (fr) * 1974-06-20 1986-01-27 Meiji Seika Co
CA1100129A (fr) * 1974-08-02 1981-04-28 William H.W. Lunn Traduction non-disponible
AU1303576A (en) * 1975-04-21 1977-10-20 Erba Carlo Spa Cephalosporins

Also Published As

Publication number Publication date
NL190703B (nl) 1994-02-01
FI780716A (fi) 1978-09-08
PL122152B1 (en) 1982-06-30
DK97378A (da) 1978-09-08
FR2383189B1 (fr) 1981-06-26
JPH025758B2 (fr) 1990-02-05
NZ186610A (en) 1979-11-01
CY1196A (en) 1983-12-31
BG31379A3 (en) 1981-12-15
CA1083141A (fr) 1980-08-05
ATA150778A (de) 1981-09-15
AU3382878A (en) 1979-09-06
EG13454A (en) 1981-12-31
DE2809058C2 (fr) 1989-02-09
SE7802530L (sv) 1978-09-08
NL7802376A (nl) 1978-09-11
FI69309C (fi) 1986-01-10
IE46437B1 (en) 1983-06-15
IL54181A0 (en) 1978-06-15
GB1597036A (en) 1981-09-03
NL190703C (nl) 1994-07-01
SE437991B (sv) 1985-03-25
CS205115B2 (en) 1981-04-30
DD137356A5 (de) 1979-08-29
FR2383189A1 (fr) 1978-10-06
AT366696B (de) 1982-04-26
PT67732A (en) 1978-04-01
IT1093504B (it) 1985-07-19
PH14596A (en) 1981-10-02
DE2809058A1 (de) 1978-09-14
ES467637A1 (es) 1980-04-01
YU51478A (en) 1982-10-31
PL205135A1 (pl) 1979-06-04
CH637964A5 (en) 1983-08-31
HK49083A (en) 1983-11-04
FI69309B (fi) 1985-09-30
AU515428B2 (en) 1981-04-02
MX5142E (es) 1983-03-30
GR68893B (fr) 1982-03-15
IL54181A (en) 1981-03-31
IT7820912A0 (it) 1978-03-06
IE780453L (en) 1978-09-07
JPS53130689A (en) 1978-11-14

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628