NZ186610A - Preparing of cephalosporins where the acetoxy group is displaced by a sulphur nucleophile - Google Patents

Preparing of cephalosporins where the acetoxy group is displaced by a sulphur nucleophile

Info

Publication number
NZ186610A
NZ186610A NZ186610A NZ18661078A NZ186610A NZ 186610 A NZ186610 A NZ 186610A NZ 186610 A NZ186610 A NZ 186610A NZ 18661078 A NZ18661078 A NZ 18661078A NZ 186610 A NZ186610 A NZ 186610A
Authority
NZ
New Zealand
Prior art keywords
cephalosporins
displaced
preparing
acetoxy group
sulphur nucleophile
Prior art date
Application number
NZ186610A
Other languages
English (en)
Inventor
Ld Hatfield
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/862,871 external-priority patent/US4144391A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NZ186610A publication Critical patent/NZ186610A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ186610A 1977-03-07 1978-03-02 Preparing of cephalosporins where the acetoxy group is displaced by a sulphur nucleophile NZ186610A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77501877A 1977-03-07 1977-03-07
US05/862,871 US4144391A (en) 1977-03-07 1977-12-27 Cephalosporin displacement reaction

Publications (1)

Publication Number Publication Date
NZ186610A true NZ186610A (en) 1979-11-01

Family

ID=27118982

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ186610A NZ186610A (en) 1977-03-07 1978-03-02 Preparing of cephalosporins where the acetoxy group is displaced by a sulphur nucleophile

Country Status (30)

Country Link
JP (1) JPS53130689A (xx)
AT (1) AT366696B (xx)
AU (1) AU515428B2 (xx)
BG (1) BG31379A3 (xx)
CA (1) CA1083141A (xx)
CH (1) CH637964A5 (xx)
CS (1) CS205115B2 (xx)
CY (1) CY1196A (xx)
DD (1) DD137356A5 (xx)
DE (1) DE2809058A1 (xx)
DK (1) DK97378A (xx)
EG (1) EG13454A (xx)
ES (1) ES467637A1 (xx)
FI (1) FI69309C (xx)
FR (1) FR2383189A1 (xx)
GB (1) GB1597036A (xx)
GR (1) GR68893B (xx)
HK (1) HK49083A (xx)
HU (1) HU179967B (xx)
IE (1) IE46437B1 (xx)
IL (1) IL54181A (xx)
IT (1) IT1093504B (xx)
MX (1) MX5142E (xx)
NL (1) NL190703C (xx)
NZ (1) NZ186610A (xx)
PH (1) PH14596A (xx)
PL (1) PL122152B1 (xx)
PT (1) PT67732A (xx)
SE (1) SE437991B (xx)
YU (1) YU51478A (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543043A (en) * 1978-09-22 1980-03-26 Sankyo Co Ltd Preparation of 3-substituted thiomethylcephalosporin derivative
US4576937A (en) * 1984-02-29 1986-03-18 Smithkline Beckman Corporation 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
JP2503500B2 (ja) * 1986-04-14 1996-06-05 萬有製薬株式会社 新規セフアロスポリン誘導体及びその製造法
JPS62281881A (ja) * 1986-09-08 1987-12-07 Sankyo Co Ltd ３−置換チオメチルセフアロスポリン誘導体の製法
EP2539348A4 (en) * 2010-02-26 2013-07-24 Gary Igor Dmitrienko CEPHALOSPORIN DERIVATIVES AS BETA LACTAMASE HEMMER AND COMPOSITIONS THEREFOR AND METHOD FOR THEIR USE
GB201818410D0 (en) * 2018-11-12 2018-12-26 Imperial Innovations Ltd Compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
JPS5116436B1 (xx) * 1971-05-31 1976-05-24
JPS5143785A (en) * 1974-10-11 1976-04-14 Yamanouchi Pharma Co Ltd Shinsefuarosuhorinkanrenkagobutsuno goseiho
JPS612674B2 (xx) * 1974-06-20 1986-01-27 Meiji Seika Co
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
FI761035A (xx) * 1975-04-21 1976-10-22 Erba Carlo Spa

Also Published As

Publication number Publication date
CY1196A (en) 1983-12-31
ES467637A1 (es) 1980-04-01
FI780716A (fi) 1978-09-08
PH14596A (en) 1981-10-02
ATA150778A (de) 1981-09-15
NL7802376A (nl) 1978-09-11
IT7820912A0 (it) 1978-03-06
AT366696B (de) 1982-04-26
GB1597036A (en) 1981-09-03
JPH025758B2 (xx) 1990-02-05
IE46437B1 (en) 1983-06-15
NL190703C (nl) 1994-07-01
SE437991B (sv) 1985-03-25
NL190703B (nl) 1994-02-01
GR68893B (xx) 1982-03-15
FI69309B (fi) 1985-09-30
FI69309C (fi) 1986-01-10
IL54181A (en) 1981-03-31
FR2383189B1 (xx) 1981-06-26
SE7802530L (sv) 1978-09-08
CA1083141A (en) 1980-08-05
PT67732A (en) 1978-04-01
IL54181A0 (en) 1978-06-15
MX5142E (es) 1983-03-30
IT1093504B (it) 1985-07-19
BG31379A3 (en) 1981-12-15
IE780453L (en) 1978-09-07
DE2809058A1 (de) 1978-09-14
YU51478A (en) 1982-10-31
AU3382878A (en) 1979-09-06
JPS53130689A (en) 1978-11-14
DK97378A (da) 1978-09-08
DE2809058C2 (xx) 1989-02-09
HU179967B (en) 1983-01-28
EG13454A (en) 1981-12-31
DD137356A5 (de) 1979-08-29
PL122152B1 (en) 1982-06-30
CH637964A5 (en) 1983-08-31
PL205135A1 (pl) 1979-06-04
FR2383189A1 (fr) 1978-10-06
HK49083A (en) 1983-11-04
AU515428B2 (en) 1981-04-02
CS205115B2 (en) 1981-04-30

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