HU176103B - Microbiological process for producing nebramycin complex - Google Patents

Microbiological process for producing nebramycin complex Download PDF

Info

Publication number
HU176103B
HU176103B HU78GO1404A HUGO001404A HU176103B HU 176103 B HU176103 B HU 176103B HU 78GO1404 A HU78GO1404 A HU 78GO1404A HU GO001404 A HUGO001404 A HU GO001404A HU 176103 B HU176103 B HU 176103B
Authority
HU
Hungary
Prior art keywords
nebramycin
complex
strains
tobramycin
isolated
Prior art date
Application number
HU78GO1404A
Other languages
English (en)
Hungarian (hu)
Inventor
Istvan Ott
Gabor Ambrus
Jozsef Gyimesi
Ilona Harsanyi
Janos Berdy
Valeria Szell
Tibor Balogh
Laszlo Toelgyesi
Istvanne Kadar
Laszlo Nagy
Janos Erdei
Endrene Szuecs
Istvan Kaszab
Ferenc Fabian
Kalman Polya
Lajos Kun
Janos Vig
Jenoe Szilagyi
Csaba Nagy
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Priority to HU78GO1404A priority Critical patent/HU176103B/hu
Priority to AT0357279A priority patent/AT363180B/de
Priority to FR7912950A priority patent/FR2426736B1/fr
Priority to DE19792921022 priority patent/DE2921022A1/de
Publication of HU176103B publication Critical patent/HU176103B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU78GO1404A 1978-05-23 1978-05-23 Microbiological process for producing nebramycin complex HU176103B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
HU78GO1404A HU176103B (en) 1978-05-23 1978-05-23 Microbiological process for producing nebramycin complex
AT0357279A AT363180B (de) 1978-05-23 1979-05-15 Verfahren zur mikrobiologischen herstellung von nebramycin-komplex
FR7912950A FR2426736B1 (fr) 1978-05-23 1979-05-22 Procede de fabrication du complexe de nebramycine par voie microbiologique
DE19792921022 DE2921022A1 (de) 1978-05-23 1979-05-23 Verfahren zur mikrobiologischen herstellung des nebramycin-komplexes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78GO1404A HU176103B (en) 1978-05-23 1978-05-23 Microbiological process for producing nebramycin complex

Publications (1)

Publication Number Publication Date
HU176103B true HU176103B (en) 1980-12-28

Family

ID=10996858

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78GO1404A HU176103B (en) 1978-05-23 1978-05-23 Microbiological process for producing nebramycin complex

Country Status (4)

Country Link
AT (1) AT363180B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2921022A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2426736B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU176103B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119331935A (zh) * 2024-11-01 2025-01-21 浙江大学 一种提高氨甲酰妥布霉素生产菌株发酵产量的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178489A (en) * 1967-04-04 1970-01-21 Lilly Co Eli Tenebrimycin Antibiotics
US3691279A (en) * 1970-04-15 1972-09-12 Lilly Co Eli Antibiotic nebramycin and preparation thereof
US3853709A (en) * 1970-10-26 1974-12-10 Lilly Co Eli Process for preparing nebramycin factors ii and vii
US3876767A (en) * 1972-02-04 1975-04-08 Lilly Co Eli Treatment of swine dysentery with apramycin
US4032404A (en) * 1976-07-14 1977-06-28 Bristol-Myers Company Fermentation process for producing apramycin and nebramycin factor V'

Also Published As

Publication number Publication date
FR2426736A1 (fr) 1979-12-21
ATA357279A (de) 1980-12-15
FR2426736B1 (fr) 1985-08-09
DE2921022A1 (de) 1979-11-29
DE2921022C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-10-15
AT363180B (de) 1981-07-10

Similar Documents

Publication Publication Date Title
FI78469B (fi) Foerfarande foer framstaellning av n-substituerade 1-desoxinojirimycinderivat.
PETERSEN et al. Production of cladospirone bisepoxide, a new fungal metabolite
SU1036251A3 (ru) Способ получени антибиотика @ -15003 @ -3
Boeck et al. NEW AZASTEROIDAL ANTIFUNGAL ANTIBIOTICS FROM GEOTRICHU FLAVO-BRUNNEUM I. DISCOVERY AND FERMENTATION STUDIES
US3716579A (en) Ester derivatives of pleuromutilin
RU2196826C2 (ru) Способ биотрансформации соединений колхициноидов в соответствующие 3-гликозилпроизводные
EP0048585A1 (en) Antibiotics TM-531 B and TM-531 C
JPS63139191A (ja) 抗腫瘍抗菌剤
Slechta et al. Isolation and characterization of a new antibiotic U-62162
JPS61148189A (ja) Ｃｌ−１５７７ｄおよびｃｌ−１５７７ｅ抗生／抗腫瘍化合物およびそれらの製法
US2885433A (en) O-carbamyl-d-serine
US3592925A (en) Antibiotics ah272alpha2 and ah272beta2 and process for producing same
HU176103B (en) Microbiological process for producing nebramycin complex
CA1154393A (en) Antibiotic em 4940
Venkata Dasu et al. Studies on production of griseofulvin
HU189515B (en) Process for preparing new 20-dihydro-20,23-dideoxy-tylonolide /tylactone/ and esters thereof
EP0042172B1 (en) Antibiotic compounds, pharmaceutical compositions containing such compounds, process for production thereof
US4239690A (en) Antibiotics produced by Cytospora sp. W.F.P.L. 13A
US4339535A (en) Process for preparing antibiotic EM 4940
US4220718A (en) Antibiotics produced by Cytospora sp. W.F.P.L. 13A
US3901880A (en) (s)-alanyl-3-(+60 -(s)-chloro-3-(s)-hydroxy-2-oxo-azetidinylmethyl)-(s)-alanine
US5364623A (en) Antibiotic produced by Bacillus subtilis ATCC 55422 capable of inhibiting bacteria
JP3100785B2 (ja) 新規エバーメクチン誘導体、その製造方法ならびにその生産微生物
US3835170A (en) Hypotensive agent, oudenone, its salts and processes for production and preparation thereof
SU352469A1 (ru) Способ получения антибиотического комплекса

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee