AT363180B - Verfahren zur mikrobiologischen herstellung von nebramycin-komplex - Google Patents

Verfahren zur mikrobiologischen herstellung von nebramycin-komplex

Info

Publication number
AT363180B
AT363180B AT0357279A AT357279A AT363180B AT 363180 B AT363180 B AT 363180B AT 0357279 A AT0357279 A AT 0357279A AT 357279 A AT357279 A AT 357279A AT 363180 B AT363180 B AT 363180B
Authority
AT
Austria
Prior art keywords
microbiological production
nebramycin
complex
nebramycin complex
microbiological
Prior art date
Application number
AT0357279A
Other languages
English (en)
Other versions
ATA357279A (de
Inventor
Istvan Dr Ott
Gabor Dr Ambrus
Jozsef Dr Gyimesi
Ilona Harsanyi
Janos Dr Berdy
Valeria Dr Szell
Tibor Dr Balogh
Laszlo Toelgyesi
I Ing Kadar
Laszlo Nagy
Janos Dr Erdei
E Szuecs
Istvan Dr Kaszab
Ferenc Fabian
Kalman Dr Polya
Lajos Kun
Janos Ing Vig
Jenoe Szilagyi
Csaba Dipl Chem Nagy
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Publication of ATA357279A publication Critical patent/ATA357279A/de
Application granted granted Critical
Publication of AT363180B publication Critical patent/AT363180B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT0357279A 1978-05-23 1979-05-15 Verfahren zur mikrobiologischen herstellung von nebramycin-komplex AT363180B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78GO1404A HU176103B (en) 1978-05-23 1978-05-23 Microbiological process for producing nebramycin complex

Publications (2)

Publication Number Publication Date
ATA357279A ATA357279A (de) 1980-12-15
AT363180B true AT363180B (de) 1981-07-10

Family

ID=10996858

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0357279A AT363180B (de) 1978-05-23 1979-05-15 Verfahren zur mikrobiologischen herstellung von nebramycin-komplex

Country Status (4)

Country Link
AT (1) AT363180B (de)
DE (1) DE2921022A1 (de)
FR (1) FR2426736B1 (de)
HU (1) HU176103B (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178489A (en) * 1967-04-04 1970-01-21 Lilly Co Eli Tenebrimycin Antibiotics
US3691279A (en) * 1970-04-15 1972-09-12 Lilly Co Eli Antibiotic nebramycin and preparation thereof
US3853709A (en) * 1970-10-26 1974-12-10 Lilly Co Eli Process for preparing nebramycin factors ii and vii
US3876767A (en) * 1972-02-04 1975-04-08 Lilly Co Eli Treatment of swine dysentery with apramycin
US4032404A (en) * 1976-07-14 1977-06-28 Bristol-Myers Company Fermentation process for producing apramycin and nebramycin factor V'

Also Published As

Publication number Publication date
HU176103B (en) 1980-12-28
DE2921022C2 (de) 1987-10-15
FR2426736B1 (fr) 1985-08-09
ATA357279A (de) 1980-12-15
DE2921022A1 (de) 1979-11-29
FR2426736A1 (fr) 1979-12-21

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee