HRPK20130487B3 - Formulacija probiotika s apigeninom i ekstraktom paprene metvice - Google Patents
Formulacija probiotika s apigeninom i ekstraktom paprene metviceInfo
- Publication number
- HRPK20130487B3 HRPK20130487B3 HRP20130487AA HRP20130487A HRPK20130487B3 HR PK20130487 B3 HRPK20130487 B3 HR PK20130487B3 HR P20130487A A HRP20130487A A HR P20130487AA HR P20130487 A HRP20130487 A HR P20130487A HR PK20130487 B3 HRPK20130487 B3 HR PK20130487B3
- Authority
- HR
- Croatia
- Prior art keywords
- lactobacillus
- apigenin
- formulation
- amount
- peppermint
- Prior art date
Links
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 229940117893 apigenin Drugs 0.000 title abstract 4
- XADJWCRESPGUTB-UHFFFAOYSA-N apigenin Natural products C1=CC(O)=CC=C1C1=CC(=O)C2=CC(O)=C(O)C=C2O1 XADJWCRESPGUTB-UHFFFAOYSA-N 0.000 title abstract 4
- 235000008714 apigenin Nutrition 0.000 title abstract 4
- 235000020737 peppermint extract Nutrition 0.000 title abstract 2
- 239000006041 probiotic Substances 0.000 title abstract 2
- 230000000529 probiotic effect Effects 0.000 title abstract 2
- 235000018291 probiotics Nutrition 0.000 title abstract 2
- 235000004357 Mentha x piperita Nutrition 0.000 abstract 3
- 241001479543 Mentha x piperita Species 0.000 abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000001771 mentha piperita Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241001608472 Bifidobacterium longum Species 0.000 abstract 1
- 241000186660 Lactobacillus Species 0.000 abstract 1
- 240000001046 Lactobacillus acidophilus Species 0.000 abstract 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 abstract 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 abstract 1
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 abstract 1
- 244000199866 Lactobacillus casei Species 0.000 abstract 1
- 235000013958 Lactobacillus casei Nutrition 0.000 abstract 1
- 241001468157 Lactobacillus johnsonii Species 0.000 abstract 1
- 241000186605 Lactobacillus paracasei Species 0.000 abstract 1
- 240000006024 Lactobacillus plantarum Species 0.000 abstract 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 abstract 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 abstract 1
- 244000246386 Mentha pulegium Species 0.000 abstract 1
- 235000016257 Mentha pulegium Nutrition 0.000 abstract 1
- 229930182473 O-glycoside Natural products 0.000 abstract 1
- 150000008444 O-glycosides Chemical class 0.000 abstract 1
- 229940009291 bifidobacterium longum Drugs 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 235000001050 hortel pimenta Nutrition 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 229940039696 lactobacillus Drugs 0.000 abstract 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 abstract 1
- 229940004208 lactobacillus bulgaricus Drugs 0.000 abstract 1
- 229940017800 lactobacillus casei Drugs 0.000 abstract 1
- 229940072205 lactobacillus plantarum Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000419 plant extract Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Alternative & Traditional Medicine (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Predmetni izum otkriva poboljšanu formulaciju probiotičkih kultura bakterija mliječne kiseline s apigeninom (1) i ekstraktom paprene metvice (Mentha piperita L.), postupak njezina dobivanja, te primjenu. Formulacija se sastoji od:(i) jedne jedne ili više liofiliziranih kultura Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus paracasei, Lactobacillus bulgaricus, Lactobacillus johnsonii, Lactobacillus delbrueckii, Bifidobacterium animalis ssp. lactis i Bifidobacterium longum; u količini od 1•10do 5•10cfu/g ili 0,01-50% m/m;(ii) apigenina (1), njegovih O-glikozida ili suhih biljnih ekstrakata koji ih sadrže:u količini od 10-50% m/m računato na sadržaj apigenina (1);(iii) suhog ekstrakta lista paprene metvice (Mentha piperita L.); u količini od 10-50% m/m; te(iv) pomoćnih tvari s kojima čine konačni dozni oblik; do 100% m/m formulacije.Formulacija se koristi kao prehrambeni, farmaceutski ili veterinarski proizvod.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HRP20130487AA HRPK20130487B3 (hr) | 2013-06-04 | 2013-06-04 | Formulacija probiotika s apigeninom i ekstraktom paprene metvice |
| PCT/HR2014/000004 WO2014195741A1 (en) | 2013-06-04 | 2014-01-27 | Probiotic formulation with apigenin and peppermint extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HRP20130487AA HRPK20130487B3 (hr) | 2013-06-04 | 2013-06-04 | Formulacija probiotika s apigeninom i ekstraktom paprene metvice |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HRP20130487A2 HRP20130487A2 (hr) | 2014-12-05 |
| HRP20130487A9 HRP20130487A9 (hr) | 2015-01-02 |
| HRPK20130487B3 true HRPK20130487B3 (hr) | 2015-07-31 |
Family
ID=50391208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20130487AA HRPK20130487B3 (hr) | 2013-06-04 | 2013-06-04 | Formulacija probiotika s apigeninom i ekstraktom paprene metvice |
Country Status (2)
| Country | Link |
|---|---|
| HR (1) | HRPK20130487B3 (hr) |
| WO (1) | WO2014195741A1 (hr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10137164B2 (en) | 2015-01-02 | 2018-11-27 | Melaleuca, Inc. | Dietary supplement compositions |
| TWI829098B (zh) * | 2015-01-02 | 2024-01-11 | 美商梅拉洛伊卡公司 | 細菌組成物 |
| TWI788111B (zh) * | 2015-01-02 | 2022-12-21 | 美商梅拉洛伊卡公司 | 多元補充品組成物 |
| CA3024156A1 (en) * | 2016-06-22 | 2017-12-28 | Dsm Ip Assets B.V. | Stable probiotic suspensions |
| US11019838B2 (en) * | 2017-02-21 | 2021-06-01 | Jarrow Formulas, Inc. | Probiotic dietary supplement formulation |
| IT201800004385A1 (it) * | 2018-04-12 | 2019-10-12 | Composizione per il trattamento di patologie gastrointestinali | |
| CN110669697B (zh) * | 2019-10-31 | 2022-07-15 | 微康益生菌(苏州)股份有限公司 | 一种高产短链脂肪酸的干酪乳杆菌、培养方法及其应用 |
| CN111000841A (zh) * | 2020-01-03 | 2020-04-14 | 陕西科技大学 | 木犀草素在抑制多重耐药阴沟肠杆菌生长中的应用 |
| CN115869403A (zh) * | 2022-08-02 | 2023-03-31 | 广州益合生物科技有限公司 | 约氏乳杆菌在制备治疗和/或预防高原缺氧环境导致的肠道屏障损伤药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4428740B2 (ja) * | 1998-09-14 | 2010-03-10 | 株式会社ロッテ | ビフィズス菌増殖促進剤 |
| US20070065456A1 (en) * | 2005-09-20 | 2007-03-22 | Woods Cindy J | Nutritional supplements |
| CN103431408B (zh) * | 2013-07-18 | 2015-08-12 | 浙江劲膳美生物科技有限公司 | 一种咽喉炎患者食用的特殊膳食 |
-
2013
- 2013-06-04 HR HRP20130487AA patent/HRPK20130487B3/hr not_active IP Right Cessation
-
2014
- 2014-01-27 WO PCT/HR2014/000004 patent/WO2014195741A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014195741A1 (en) | 2014-12-11 |
| HRP20130487A9 (hr) | 2015-01-02 |
| HRP20130487A2 (hr) | 2014-12-05 |
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