HRP20251413T1 - Nove soli trimetazidina - Google Patents

Nove soli trimetazidina

Info

Publication number
HRP20251413T1
HRP20251413T1 HRP20251413TT HRP20251413T HRP20251413T1 HR P20251413 T1 HRP20251413 T1 HR P20251413T1 HR P20251413T T HRP20251413T T HR P20251413TT HR P20251413 T HRP20251413 T HR P20251413T HR P20251413 T1 HRP20251413 T1 HR P20251413T1
Authority
HR
Croatia
Prior art keywords
trimetazidine
acid
pharmaceutical composition
composition according
salt
Prior art date
Application number
HRP20251413TT
Other languages
English (en)
Croatian (hr)
Inventor
Julien MAHIEUX
Frédéric VILLARD
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of HRP20251413T1 publication Critical patent/HRP20251413T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20251413TT 2021-10-20 2022-10-19 Nove soli trimetazidina HRP20251413T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21306465 2021-10-20
EP22808665.8A EP4419510B1 (en) 2021-10-20 2022-10-19 Novel trimetazidine salts
PCT/EP2022/079054 WO2023066971A1 (en) 2021-10-20 2022-10-19 Novel trimetazidine salts

Publications (1)

Publication Number Publication Date
HRP20251413T1 true HRP20251413T1 (hr) 2025-12-19

Family

ID=78592764

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20251413TT HRP20251413T1 (hr) 2021-10-20 2022-10-19 Nove soli trimetazidina

Country Status (20)

Country Link
US (1) US20250250245A1 (enExample)
EP (1) EP4419510B1 (enExample)
JP (1) JP2024539090A (enExample)
KR (1) KR20240093576A (enExample)
CN (1) CN118076591A (enExample)
AR (1) AR127403A1 (enExample)
AU (1) AU2022369026A1 (enExample)
CR (1) CR20240157A (enExample)
DK (1) DK4419510T3 (enExample)
ES (1) ES3057370T3 (enExample)
HR (1) HRP20251413T1 (enExample)
IL (1) IL311916A (enExample)
LT (1) LT4419510T (enExample)
MA (1) MA66951B1 (enExample)
MX (1) MX2024004714A (enExample)
PL (1) PL4419510T3 (enExample)
PT (1) PT4419510T (enExample)
RS (1) RS67449B1 (enExample)
SI (1) SI4419510T1 (enExample)
WO (1) WO2023066971A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025106477A1 (en) * 2023-11-14 2025-05-22 Samsara Therapeutics Inc. Novel autophagy inducing compounds and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104138376A (zh) * 2013-05-06 2014-11-12 常州高新技术产业开发区三维工业技术研究所有限公司 一种提高缺氧耐受力的缓释剂
FR3027803B1 (fr) 2014-11-05 2018-02-09 Les Laboratoires Servier Composition pharmaceutique comprenant un betabloquant et un inhibiteur de l'enzyme de conversion
CN105287564A (zh) * 2015-09-06 2016-02-03 余祖江 一种防治肝病的西药复合物及其用途
CN110183398B (zh) 2019-05-14 2021-06-29 中南民族大学 一种曲美他嗪草酸盐及其制备方法和应用
CN110105307B (zh) 2019-05-14 2021-06-01 中南民族大学 一种曲美他嗪草酸盐及其制备方法和应用
CN110054599B (zh) * 2019-05-14 2021-05-07 中南民族大学 一种曲美他嗪草酸盐及其制备方法和应用
CN112043691A (zh) * 2019-06-06 2020-12-08 常州高新技术产业开发区三维工业技术研究所有限公司 一种药物组合物及其用途

Also Published As

Publication number Publication date
IL311916A (en) 2024-06-01
CR20240157A (es) 2024-05-22
EP4419510B1 (en) 2025-10-08
ES3057370T3 (en) 2026-03-02
WO2023066971A1 (en) 2023-04-27
JP2024539090A (ja) 2024-10-28
LT4419510T (lt) 2025-12-29
CN118076591A (zh) 2024-05-24
CA3234743A1 (en) 2023-04-27
US20250250245A1 (en) 2025-08-07
RS67449B1 (sr) 2025-12-31
AR127403A1 (es) 2024-01-17
KR20240093576A (ko) 2024-06-24
EP4419510A1 (en) 2024-08-28
MA66951B1 (fr) 2025-12-31
AU2022369026A1 (en) 2024-05-02
PT4419510T (pt) 2026-01-02
SI4419510T1 (sl) 2026-01-30
MX2024004714A (es) 2024-05-10
DK4419510T3 (da) 2025-11-17
PL4419510T3 (pl) 2026-02-16

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