HRP20230369T1 - N-acetilcistein za uporabu kao antibakterijsko sredstvo - Google Patents
N-acetilcistein za uporabu kao antibakterijsko sredstvo Download PDFInfo
- Publication number
- HRP20230369T1 HRP20230369T1 HRP20230369TT HRP20230369T HRP20230369T1 HR P20230369 T1 HRP20230369 T1 HR P20230369T1 HR P20230369T T HRP20230369T T HR P20230369TT HR P20230369 T HRP20230369 T HR P20230369T HR P20230369 T1 HRP20230369 T1 HR P20230369T1
- Authority
- HR
- Croatia
- Prior art keywords
- nac
- use according
- maltophilia
- bcc
- acetylcysteine
- Prior art date
Links
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title claims 7
- 229960004308 acetylcysteine Drugs 0.000 title claims 7
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 208000017667 Chronic Disease Diseases 0.000 claims 3
- 241000122973 Stenotrophomonas maltophilia Species 0.000 claims 3
- 244000052769 pathogen Species 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010061598 Immunodeficiency Diseases 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 230000005713 exacerbation Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (5)
1. N-acetilcistein (NAC), naznačen time, da je za terapijsku uporabu u inhibiranju ili zaustavljanju rasta i/ili usmrćivanju soja pristupačnog za obradu, odabranog od BCC i S. maltophilia.
2. NAC za uporabu prema patentnom zahtjevu 1, naznačen time, da je za liječenje bakterijske infekcije putem pristupačnog soja patogena odabranog od BCC i S. maltophilia.
3. NAC za uporabu prema patentnom zahtjevu 2, naznačen time, da je za liječenje epizoda plućnih pogoršanja uzrokovanih barem djelomično putem pristupačnog soja patogena odabranog od BCC i S. maltophilia, kod pojedinca koji boluje od kronične bolesti koja također pogađa donji respiratorni sustav.
4. NAC za uporabu prema patentnom zahtjevu 3, naznačen time, da kronična bolest je cistična fibroza ili kronična opstrukcijska plućna bolest.
5. NAC za uporabu prema patentnom zahtjevu 4, naznačen time, da su pojedinci koji boluju od kronične bolesti, imunokompromitirani bolesnici i/ili hospitalizirani pacijenti.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16204412 | 2016-12-15 | ||
| PCT/EP2017/082512 WO2018108960A1 (en) | 2016-12-15 | 2017-12-13 | N-acetylcysteine for use as antibacterial agent |
| EP17825431.4A EP3554491B1 (en) | 2016-12-15 | 2017-12-13 | N-acetylcysteine for use as antibacterial agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20230369T1 true HRP20230369T1 (hr) | 2023-06-23 |
Family
ID=57614136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20230369TT HRP20230369T1 (hr) | 2016-12-15 | 2017-12-13 | N-acetilcistein za uporabu kao antibakterijsko sredstvo |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20200093774A1 (hr) |
| EP (2) | EP3861994A1 (hr) |
| JP (1) | JP2020502096A (hr) |
| CN (1) | CN110049761A (hr) |
| AU (1) | AU2017376391B2 (hr) |
| BR (1) | BR112019011708A2 (hr) |
| CA (1) | CA3045730A1 (hr) |
| CO (1) | CO2019006311A2 (hr) |
| DK (1) | DK3554491T3 (hr) |
| EA (1) | EA201991331A1 (hr) |
| ES (1) | ES2942764T3 (hr) |
| FI (1) | FI3554491T3 (hr) |
| HR (1) | HRP20230369T1 (hr) |
| HU (1) | HUE061995T2 (hr) |
| LT (1) | LT3554491T (hr) |
| PL (1) | PL3554491T3 (hr) |
| PT (1) | PT3554491T (hr) |
| RS (1) | RS64201B1 (hr) |
| SI (1) | SI3554491T1 (hr) |
| WO (1) | WO2018108960A1 (hr) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1231012B (it) * | 1989-07-27 | 1991-11-08 | Zambon Spa | Composizione farmaceutica per uso orale contenente nac. |
| AU2042200A (en) * | 1998-12-07 | 2000-06-26 | Baylor College Of Medicine | Preventing and removing biofilm from the surface of medical devices |
| US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| US6566401B2 (en) | 2001-03-30 | 2003-05-20 | The Board Of Trustees Of The Leland Stanford Junior University | N-acetylcysteine compositions and methods for the treatment and prevention of drug toxicity |
| ITMI20021405A1 (it) * | 2002-06-25 | 2003-12-29 | Zambon Spa | Composizioni farmaceutiche per il trattamento di infezioni da patogeni dell'apparato respiratorio |
| US8148356B2 (en) * | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| CA2662636C (en) | 2008-04-15 | 2017-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | N-acetylcysteine compositions and methods for treating acute exacerbations of inflammatory lung disease |
| GB0905451D0 (en) * | 2009-03-31 | 2009-05-13 | Novabiotics Ltd | Biofilms |
| IT1399492B1 (it) | 2010-04-13 | 2013-04-19 | Alpex Pharma Sa | Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina. |
| GB201021186D0 (en) * | 2010-12-14 | 2011-01-26 | Novabiotics Ltd | Composition |
| ITMI20130874A1 (it) | 2013-05-29 | 2014-11-30 | Zambon Spa | Compresse deglutibili di n-acetilcisteina |
| JP6596421B2 (ja) * | 2013-08-23 | 2019-10-23 | パリオン・サイエンシィズ・インコーポレーテッド | ジチオール粘液溶解薬 |
| WO2016120787A1 (en) | 2015-01-26 | 2016-08-04 | Novartis Consumer Health S.A. | Oral n-acetylcysteine in the treatment of upper respiratory tract infections and symptoms |
-
2017
- 2017-12-13 EA EA201991331A patent/EA201991331A1/ru unknown
- 2017-12-13 HR HRP20230369TT patent/HRP20230369T1/hr unknown
- 2017-12-13 WO PCT/EP2017/082512 patent/WO2018108960A1/en unknown
- 2017-12-13 HU HUE17825431A patent/HUE061995T2/hu unknown
- 2017-12-13 ES ES17825431T patent/ES2942764T3/es active Active
- 2017-12-13 EP EP21163647.7A patent/EP3861994A1/en active Pending
- 2017-12-13 CN CN201780076376.2A patent/CN110049761A/zh active Pending
- 2017-12-13 PL PL17825431.4T patent/PL3554491T3/pl unknown
- 2017-12-13 AU AU2017376391A patent/AU2017376391B2/en active Active
- 2017-12-13 US US16/468,716 patent/US20200093774A1/en not_active Abandoned
- 2017-12-13 FI FIEP17825431.4T patent/FI3554491T3/fi active
- 2017-12-13 LT LTEPPCT/EP2017/082512T patent/LT3554491T/lt unknown
- 2017-12-13 PT PT178254314T patent/PT3554491T/pt unknown
- 2017-12-13 JP JP2019531147A patent/JP2020502096A/ja active Pending
- 2017-12-13 BR BR112019011708A patent/BR112019011708A2/pt active Search and Examination
- 2017-12-13 DK DK17825431.4T patent/DK3554491T3/da active
- 2017-12-13 SI SI201731343T patent/SI3554491T1/sl unknown
- 2017-12-13 EP EP17825431.4A patent/EP3554491B1/en active Active
- 2017-12-13 RS RS20230305A patent/RS64201B1/sr unknown
- 2017-12-13 CA CA3045730A patent/CA3045730A1/en active Pending
-
2019
- 2019-06-17 CO CONC2019/0006311A patent/CO2019006311A2/es unknown
-
2020
- 2020-12-28 US US17/134,719 patent/US11918552B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20210113508A1 (en) | 2021-04-22 |
| US20200093774A1 (en) | 2020-03-26 |
| CA3045730A1 (en) | 2018-06-21 |
| RS64201B1 (sr) | 2023-06-30 |
| EP3861994A1 (en) | 2021-08-11 |
| EP3554491A1 (en) | 2019-10-23 |
| PL3554491T3 (pl) | 2023-07-17 |
| EA201991331A1 (ru) | 2019-11-29 |
| BR112019011708A2 (pt) | 2019-10-15 |
| AU2017376391B2 (en) | 2023-06-01 |
| FI3554491T3 (fi) | 2023-04-26 |
| ES2942764T3 (es) | 2023-06-06 |
| LT3554491T (lt) | 2023-05-25 |
| WO2018108960A1 (en) | 2018-06-21 |
| CO2019006311A2 (es) | 2020-01-17 |
| HUE061995T2 (hu) | 2023-09-28 |
| EP3554491B1 (en) | 2023-02-15 |
| JP2020502096A (ja) | 2020-01-23 |
| AU2017376391A1 (en) | 2019-06-20 |
| SI3554491T1 (sl) | 2023-06-30 |
| DK3554491T3 (en) | 2023-05-15 |
| US11918552B2 (en) | 2024-03-05 |
| CN110049761A (zh) | 2019-07-23 |
| PT3554491T (pt) | 2023-05-04 |
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