HRP20220378T1 - Kompozicija koja oblikuje lipidni sloj za primjenu na površinu živog organizma - Google Patents

Kompozicija koja oblikuje lipidni sloj za primjenu na površinu živog organizma Download PDF

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Publication number
HRP20220378T1
HRP20220378T1 HRP20220378TT HRP20220378T HRP20220378T1 HR P20220378 T1 HRP20220378 T1 HR P20220378T1 HR P20220378T T HRP20220378T T HR P20220378TT HR P20220378 T HRP20220378 T HR P20220378T HR P20220378 T1 HRP20220378 T1 HR P20220378T1
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Croatia
Prior art keywords
agent
composition according
weight
silicone oil
lipid layer
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HRP20220378TT
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English (en)
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Jan HOLMBÄCK
Anders Carlsson
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Lipidor Ab
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Publication of HRP20220378T1 publication Critical patent/HRP20220378T1/hr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • AHUMAN NECESSITIES
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
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    • A61P33/14Ectoparasiticides, e.g. scabicides
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
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  • Anesthesiology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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Claims (10)

1. Kompozicija nosača za topikalnu primjenu koja oblikuje lipidni sloj na koži ili membrani sluznice i sadrži isparljivo silikonsko ulje, od 10 težinskih % do 30 težinskih % fosfolipida, od 10 težinskih % do 30 težinskih % etanola, izborno vodu u količini od 5 težinskih % ili manje, pri čemu je silikonsko ulje sa točkom ključanja iznad 180°C, posebno iznad 200°C, i pri čemu je silikonsko ulje sa toplinom vaporizacije (kJ/kg) na 25°C od oko 100 kJ/kg do oko 300 kJ/kg, pod uvjetom da sadržaj isparljivog silikonskog ulja iznosi 50 težinskih % ili više.
2. Kompozicija prema patentnom zahtjevu 1, gdje je silikonsko ulje sa toplinom vaporizacije (kJ/kg) na 25 °C od 120 kJ/kg do 200 kJ/kg, posebno od 140 kJ/kg do 180 kJ/kg.
3. Kompozicija prema patentnom zahtjevu 1 ili 2, gdje isparljivo silikonsko ulje sadrži jedan od dekametilciklopentasiloksana i dodekametilcikloheksasiloksana.
4. Kompozicija prema patentnom zahtjevu 1 ili 2, gdje isparljivo silikonsko ulje sadrži jedan od heptasiloksana i oktasiloksana.
5. Kompozicija prema bilo kojem od patentnih zahtjeva od 1 do 4, koja sadrži manje od 1 težinskih % vode.
6. Farmaceutska ili kozmetička kompozicija koja oblikuje lipidni sloj i sadrži kompoziciju nosača prema bilo kojem od patentnih zahtjeva od 1 do 5 i farmakološki ili kozmetički aktivno sredstvo ili protektivno sredstvo.
7. Kompozicija prema patentnom zahtjevu 6, gdje je sredstvo farmakološki aktivno sredstvo izabrano iz grupe koju čine: antimikrobno sredstvo, antibiotik; antimikotik; antibakterijsko sredstvo; sredstvo protiv gljivica; antivirusno sredstvo; antiseptik; anti-flogistik; sredstvo protiv svraba; sredstvo protiv psorijaze; sredstvo protiv kašlja; sredstvo protiv alopecije; sredstvo protiv akni; protuupalno sredstvo; sredstvo protiv čira; lokalni anestetik.
8. Kompozicija prema patentnom zahtjevu 6, gdje je sredstvo kozmetički aktivno sredstvo izabrano iz grupe koju čine: antiperspirant; antisudoralno sredstvo; sredstvo protiv peruti; sredstvo za klizanje; sredstvo za vlaženje kože.
9. Kompozicija prema patentnom zahtjevu 6, gdje je sredstvo zaštitno sredstvo izabrano iz grupe koju čine: sredstvo koje apsorbira UV zračenje, repelent insekata, antibakterijsko sredstvo, sredstvo protiv gljivica; antivirusno sredstvo, sredstvo protiv nematoda.
10. Kompozicija prema bilo kojem od patentnih zahtjeva od 1 do 9 za kontrolu transepidermalnog gubitka vode.
HRP20220378TT 2009-11-03 2010-11-03 Kompozicija koja oblikuje lipidni sloj za primjenu na površinu živog organizma HRP20220378T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0901409 2009-11-03
EP10828610.5A EP2496263B1 (en) 2009-11-03 2010-11-03 Lipid layer forming composition for administration onto a surface of a living organism
PCT/SE2010/000268 WO2011056115A1 (en) 2009-11-03 2010-11-03 Lipid layer forming composition for administration onto a surface of a living organism

Publications (1)

Publication Number Publication Date
HRP20220378T1 true HRP20220378T1 (hr) 2022-05-13

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HRP20220378TT HRP20220378T1 (hr) 2009-11-03 2010-11-03 Kompozicija koja oblikuje lipidni sloj za primjenu na površinu živog organizma

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Country Link
US (2) US9884119B2 (hr)
EP (1) EP2496263B1 (hr)
JP (2) JP5877790B2 (hr)
KR (1) KR101748224B1 (hr)
CN (1) CN102665766B (hr)
AU (1) AU2010316005B2 (hr)
CA (1) CA2779432C (hr)
CY (1) CY1125098T1 (hr)
DK (1) DK2496263T3 (hr)
ES (1) ES2908689T3 (hr)
HK (1) HK1173666A1 (hr)
HR (1) HRP20220378T1 (hr)
HU (1) HUE057866T2 (hr)
IL (1) IL219438A (hr)
NZ (1) NZ599933A (hr)
PL (1) PL2496263T3 (hr)
PT (1) PT2496263T (hr)
RS (1) RS63043B1 (hr)
RU (1) RU2578430C2 (hr)
SI (1) SI2496263T1 (hr)
WO (1) WO2011056115A1 (hr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2496263T3 (da) 2009-11-03 2022-03-28 Lipidor Ab Lipidlagsdannende sammensætning til administration på en overflade af en levende organisme
US20140044779A1 (en) * 2011-04-18 2014-02-13 Lipidor Ab Liquid Carrier for Oral Delivery of a Pharmacologically Active Agent
SE1300709A1 (sv) * 2013-11-14 2015-05-15 Lipidor Ab Komposition och metod för topikal behandling
AU2012251135A1 (en) * 2011-05-02 2013-11-07 Lipidor Ab Treatment of psoriasis
AU2012273210B2 (en) 2011-06-18 2016-01-07 Thompson Cooper Laboratories, Llc Compositions for depositing agents using highly volatile silicone solvents
JP6244101B2 (ja) * 2013-04-24 2017-12-06 ロート製薬株式会社 ミノキシジル含有外用組成物
JP6261874B2 (ja) * 2013-04-24 2018-01-17 ロート製薬株式会社 ミノキシジル含有外用組成物
BR112015027436A8 (pt) * 2013-05-03 2018-01-16 Lipidor Ab composição tópica e veículo para administração de ingredientes farmaceuticamente ou cosmeticamente ativos
ES2745093T5 (es) * 2013-11-14 2022-11-10 Lipidor Ab Portador tópico pulverizable y composición que comprende fosfatidilcolina
JP2017210480A (ja) * 2017-08-07 2017-11-30 ロート製薬株式会社 ミノキシジル含有外用組成物
JP2017226692A (ja) * 2017-09-05 2017-12-28 ロート製薬株式会社 ミノキシジル含有外用組成物
JP2018199738A (ja) * 2018-10-02 2018-12-20 ロート製薬株式会社 ミノキシジル含有外用組成物
JP2018199739A (ja) * 2018-10-02 2018-12-20 ロート製薬株式会社 ミノキシジル含有外用組成物
JP2020189883A (ja) * 2020-08-24 2020-11-26 ロート製薬株式会社 ミノキシジル含有外用組成物
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