HRP20211604T1 - Kompozicije za liječenje i prevenciju bolesti kopita i kandži - Google Patents
Kompozicije za liječenje i prevenciju bolesti kopita i kandži Download PDFInfo
- Publication number
- HRP20211604T1 HRP20211604T1 HRP20211604TT HRP20211604T HRP20211604T1 HR P20211604 T1 HRP20211604 T1 HR P20211604T1 HR P20211604T T HRP20211604T T HR P20211604TT HR P20211604 T HRP20211604 T HR P20211604T HR P20211604 T1 HRP20211604 T1 HR P20211604T1
- Authority
- HR
- Croatia
- Prior art keywords
- dsm
- trichophyton
- composition
- antigenic material
- use according
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 15
- 210000000078 claw Anatomy 0.000 title claims 5
- 201000010099 disease Diseases 0.000 title claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims 5
- 210000000003 hoof Anatomy 0.000 title claims 5
- 230000002265 prevention Effects 0.000 title claims 3
- 230000000890 antigenic effect Effects 0.000 claims 15
- 239000000463 material Substances 0.000 claims 15
- 241000893966 Trichophyton verrucosum Species 0.000 claims 11
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 8
- 229940055035 trichophyton verrucosum Drugs 0.000 claims 7
- 241000222122 Candida albicans Species 0.000 claims 5
- 241000233866 Fungi Species 0.000 claims 5
- 241000223229 Trichophyton rubrum Species 0.000 claims 5
- 229940095731 candida albicans Drugs 0.000 claims 5
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical group NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 claims 4
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N pentanoic acid group Chemical group C(CCCC)(=O)O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 claims 4
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 claims 3
- 241001480043 Arthrodermataceae Species 0.000 claims 3
- 229920001661 Chitosan Polymers 0.000 claims 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims 3
- 102000002068 Glycopeptides Human genes 0.000 claims 3
- 108010015899 Glycopeptides Proteins 0.000 claims 3
- 241000893980 Microsporum canis Species 0.000 claims 3
- 241001045770 Trichophyton mentagrophytes Species 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 230000037304 dermatophytes Effects 0.000 claims 3
- 150000004676 glycans Chemical class 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 3
- 239000005017 polysaccharide Substances 0.000 claims 3
- 108010022457 polysaccharide peptide Proteins 0.000 claims 3
- 206010007882 Cellulitis Diseases 0.000 claims 2
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical group OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 2
- 208000006413 Digital Dermatitis Diseases 0.000 claims 2
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Chemical group O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims 2
- 241000223238 Trichophyton Species 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 208000023867 digital dermatitis in cattle Diseases 0.000 claims 2
- 229940097043 glucuronic acid Drugs 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical group CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 208000030175 lameness Diseases 0.000 claims 2
- XGISHOFUAFNYQF-UHFFFAOYSA-N pentanoyl chloride Chemical group CCCCC(Cl)=O XGISHOFUAFNYQF-UHFFFAOYSA-N 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 229940005605 valeric acid Drugs 0.000 claims 2
- YCHXNMPJFFEIJG-UHFFFAOYSA-N 3-methyloxiran-2-one Chemical compound CC1OC1=O YCHXNMPJFFEIJG-UHFFFAOYSA-N 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 1
- 241000282994 Cervidae Species 0.000 claims 1
- 206010012504 Dermatophytosis Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 241001480037 Microsporum Species 0.000 claims 1
- 241001460074 Microsporum distortum Species 0.000 claims 1
- 241000893976 Nannizzia gypsea Species 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 208000002474 Tinea Diseases 0.000 claims 1
- 241000893962 Trichophyton equinum Species 0.000 claims 1
- 229960004050 aminobenzoic acid Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000416 hydrocolloid Chemical group 0.000 claims 1
- 230000002519 immonomodulatory effect Effects 0.000 claims 1
- 239000004310 lactic acid Chemical group 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 claims 1
- 229960004906 thiomersal Drugs 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
Claims (14)
1. Kompozicija koja sadrži antigeni materijal keratinofilnih gljivica i/ili keratinofilnih kvasaca za primjenu u postupku liječenja i/ili prevencije bolesti kopita i kandži kod šupljorožaca i/ili svinja, točnije kod goveda, pri čemu su bolesti kopita i kandži odabrane iz grupe koja se sastoji od digitalnog dermatitisa, interdigitalnog dermatitisa i/ili interdigitalne flegmone a antigeni materijal sadrži antigene keratinofilnih gljivica i/ili keratinofilnih kvasaca.
2. Kompozicija za primjenu prema zahtjevu 1, pri čemu antigeni materijal keratinofilnih gljivica i/ili kvasaca sadrži homogenizirane inaktivirane mikrokonidije dermatofita i/ili homogenizirane inaktivirane blastospore kvasaca i/ili antigeni materijal mikrokonidija dermatofita i/ili antigeni materijal blastospora kvasaca.
3. Kompozicija za primjenu prema zahtjevu 2, pri čemu antigeni materijal mikrokonidija dermatofita i/ili antigeni materijal blastospora kvasaca sadrži antigeni materijal, netopiv u vodenim otopinama, koji sadrži polisaharid i/ili glikopeptid (ANMP), antigeni materijal, topiv u vodenim otopinama, koji sadrži polisaharid i/ili glikopeptid (ASMP) ili antigeni egzogeni materijal koji sadrži polisaharid i/ili glikopeptid (AEMP).
4. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu bolesti kopita i kandži rezultiraju šepanjem.
5. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu je antigeni materijal keratinofilnih gljivica i/ili keratinofilnih kvasaca izveden iz vrsta Trichophyton, naročito Trichophyton verrucosum, Trichophyton mentagrophytes, Trichophyton equinum, Trichophyton sarkisovii, Trichophyton rubrum ili Trichophyton mentagrophytes, Microsporum, naročito Microsporum gypseum, Microsporum canis, naročito Microsporum canis var. obesum ili Microsporum canis var. distortum i/ili Candida, naročito Candida albicans.
6. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu je antigeni materijal keratinofilnih gljivica izveden iz sojeva Trichophyton mentagrophytes DSM - 7279, Trichophyton verrucosum DSM - 28406, Trichophyton rubrum DSM - 9469, Trichophyton rubrum DSM - 9470, Trichophyton rubrum DSM - 9471 ili Trichophyton rubrum DSM - 9472 i/ili je antigeni materijal keratinofilnih kvasaca izveden iz sojeva Candida albicans DSM - 9456, Candida albicans DSM - 9457, Candida albicans DSM - 9458 ili Candida albicans DSM - 9459.
7. Kompozicija za primjenu prema bilo kojem od zahtjeva 2 do 6, pri čemu su mikrokonidije u otečenom stanju i/ili imaju klijajuće cjevčice.
8. Kompozicija za primjenu prema bilo kojem od zahtjeva 2 do 7, pri čemu su blastospore i/ili mikrokonidije inaktivirane tiomersalom, formaldehidom i/ili 2-propiolaktonom.
9. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu kompozicija dodatno sadrži jednu ili više imunomodulatornih supstanci.
10. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu kompozicija dodatno sadrži hitozan modificiran valerinskom kiselinom, mliječnom kiselinom, para-aminobenzojevom kiselinom, glukuronskom kiselinom ili kloridom valerinske kiseline ili hidrokoloidom koja sadrži:
(i) 0.1% do 5% (w/v) hitozana i 0.001 do 5% (w/v) valerinske kiseline, ili njene soli, poželjno klorida valerinske kiseline, ili
(ii) 0.1% do 5% (w/w) hitozana i 0.001 do 5% glukuronske kiseline ili (w/w) p-aminobenzojeve kiseline ili njihove soli.
11. Kompozicija za primjenu prema bilo kojem od prethodnih zahtjeva, pri čemu je kompozicija farmaceutska kompozicija, poželjno cjepivo.
12. Soj Trichophyton verrucosum DSM - 28406.
13. Soj Trichophyton verrucosum DSM - 28406, homogenizirana inaktivirana mikrokonidija dermatofita Trichophyton verrucosum DSM - 28406 ili antigeni materijal koji sadrži antigene soja Trichophyton verrucosum DSM - 28406 uključujući ANMP, AEMP i ASMP mikrokonidija dermatofita Trichophyton verrucosum DSM – 28406 za primjenu u humanoj i/ili veterinarskoj medicini i/ili kao cjepivo.
14. Trichophyton verrucosum DSM - 28406, homogenizirana inaktivirana mikrokonidija dermatofita Trichophyton verrucosum DSM - 28406 ili antigeni materijal koji sadrži antigene soja Trichophyton verrucosum DSM- 28406 uključujući ANMP, AEMP i ASMP mikrokonidija dermatofita Trichophyton verrucosum DSM- 28406 za primjenu u postupku liječenja i/ili prevencije bolesti kopita i kandži odabranih iz grupe koja se sastoji od digitalnog dermatitisa, interdigitalnog dermatitisa i/ili interdigitalne flegmone, šepavosti ili dermatofitoze kod životinja i/ili bradavica kod ljudi.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16160532 | 2016-03-15 | ||
| EP17710307.4A EP3429616B1 (en) | 2016-03-15 | 2017-03-15 | Compositions for the treatment and prevention of hoof and claw diseases |
| PCT/EP2017/056145 WO2017158039A1 (en) | 2016-03-15 | 2017-03-15 | Compositions for the treatment and prevention of hoof and claw diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20211604T1 true HRP20211604T1 (hr) | 2022-01-21 |
Family
ID=55628747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20211604TT HRP20211604T1 (hr) | 2016-03-15 | 2017-03-15 | Kompozicije za liječenje i prevenciju bolesti kopita i kandži |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11534483B2 (hr) |
| EP (1) | EP3429616B1 (hr) |
| CN (1) | CN109414486B (hr) |
| AU (1) | AU2017234985B2 (hr) |
| CA (1) | CA3017654C (hr) |
| CY (1) | CY1124760T1 (hr) |
| DK (1) | DK3429616T3 (hr) |
| EA (1) | EA201891932A1 (hr) |
| ES (1) | ES2894370T3 (hr) |
| HR (1) | HRP20211604T1 (hr) |
| HU (1) | HUE055935T2 (hr) |
| IL (1) | IL261779B (hr) |
| LT (1) | LT3429616T (hr) |
| MX (1) | MX2018010710A (hr) |
| PL (1) | PL3429616T3 (hr) |
| PT (1) | PT3429616T (hr) |
| RS (1) | RS62442B1 (hr) |
| SI (1) | SI3429616T1 (hr) |
| WO (1) | WO2017158039A1 (hr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3429616T1 (sl) | 2016-03-15 | 2021-12-31 | Igor Polyakov | Sestavki za zdravljenje in preprečevanje bolezni kopit in krempljev |
| RU2655521C1 (ru) * | 2017-12-07 | 2018-05-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Белгородский государственный аграрный университет имени В.Я. Горина" | Препарат для лечения пальцевого дерматита и язвы подошвы крупного рогатого скота |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU835446A1 (ru) | 1978-06-07 | 1981-06-07 | Всесоюзный Ордена Ленина Институтэкспериментальной Ветеринариивсесоюзной Ордена Ленина Академиисельскохозяйственных Науким. B.И.Ленина | Вакцина дл специфической профилактики и лЕчЕНи ТРиХОфиТии пушНыХ зВЕРЕй иКРОлиКОВ-MEHTABAK,СпОСОб изгОТОВлЕНи ВАКциНы и СпОСОб EE иСпОльзОВАНи |
| CA2011896C (en) | 1989-04-21 | 2001-05-08 | Mark Werner | Ringworm vaccine |
| UA18803A (uk) | 1990-01-15 | 1997-12-25 | Запорізький Автомобільний Завод "Комунар" | Спосіб обробки поверхhі листа |
| RU2020959C1 (ru) | 1991-10-21 | 1994-10-15 | Игорь Дмитриевич Поляков | Вакцина поливак-тм для профилактики и лечения дерматофитозов животных |
| UA42681C2 (uk) | 1994-04-28 | 2001-11-15 | Всеросійський Державний Науково-Дослідний Інститут Контролю, Стандартизації Та Сертифікації Ветеринарних Препаратів (Вднкі) | Вакцина проти трихофітії тварин |
| RU2074251C1 (ru) * | 1994-07-01 | 1997-02-27 | Всероссийский государственный научно-исследовательский институт контроля, стандартизации и сертификации ветеринарных препаратов | Штамм гриба trichophyton verrucosum, используемый для изготовления вакцины против дерматофитозов животных |
| RU2093178C1 (ru) * | 1995-03-16 | 1997-10-20 | Всероссийский научно-исследовательский институт экспериментальной ветеринарии им.Я.Р.Коваленко | Ассоциированная вакцина против трихофитии рогатого скота и других парнокопытных |
| GB2304347A (en) * | 1995-08-11 | 1997-03-19 | Boeringer Ingelheim Vetmedica | Antigenic preparations |
| EP0834322A3 (en) | 1996-10-04 | 1998-04-22 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Mycosis vaccine |
| UA25296C2 (uk) | 1998-05-26 | 2002-04-15 | Олександр Олександрович Воробйов | Ливарна відцентрова машина |
| US7097860B2 (en) * | 2001-08-03 | 2006-08-29 | Aaron Moshenyat | Method and composition for treatment of inflammatory and inflammation-related disorders |
| GB0526120D0 (en) | 2005-12-22 | 2006-02-01 | Novabiotics Ltd | Therapeutic peptides |
| UA21449U (en) | 2006-10-02 | 2007-03-15 | Vitalii Yosypovych Izdepskyi | Method for treating pyo-inflammatory process in distal part of limb in cows |
| US8889727B2 (en) | 2011-01-30 | 2014-11-18 | Meiji Seika Pharma Co., Ltd. | Topical antifungal agent |
| WO2013033400A2 (en) | 2011-08-31 | 2013-03-07 | Perosphere Inc. | Methods for effectively and rapidly desensitizing allergic patients |
| CN102727887B (zh) | 2012-07-12 | 2014-04-02 | 中国人民解放军第三军医大学第二附属医院 | 壳聚糖作为免疫佐剂在制备小鼠过敏性哮喘模型中的用途 |
| US9750245B2 (en) | 2013-03-08 | 2017-09-05 | Laboratoire M2 | Topical use of an antimicrobial formulation |
| FR3038404B1 (fr) | 2015-07-02 | 2019-04-26 | Viaccess | Procede et systeme d'execution securisee de machines virtuelles par un ensemble de dispositifs programmables interconnectes |
| SI3429616T1 (sl) | 2016-03-15 | 2021-12-31 | Igor Polyakov | Sestavki za zdravljenje in preprečevanje bolezni kopit in krempljev |
| WO2017158040A1 (en) | 2016-03-15 | 2017-09-21 | Igor Polyakov | New immunobiological products |
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2017
- 2017-03-15 SI SI201730945T patent/SI3429616T1/sl unknown
- 2017-03-15 AU AU2017234985A patent/AU2017234985B2/en active Active
- 2017-03-15 RS RS20211261A patent/RS62442B1/sr unknown
- 2017-03-15 EP EP17710307.4A patent/EP3429616B1/en active Active
- 2017-03-15 CN CN201780018505.2A patent/CN109414486B/zh active Active
- 2017-03-15 HR HRP20211604TT patent/HRP20211604T1/hr unknown
- 2017-03-15 PL PL17710307T patent/PL3429616T3/pl unknown
- 2017-03-15 LT LTEPPCT/EP2017/056145T patent/LT3429616T/lt unknown
- 2017-03-15 CA CA3017654A patent/CA3017654C/en active Active
- 2017-03-15 ES ES17710307T patent/ES2894370T3/es active Active
- 2017-03-15 WO PCT/EP2017/056145 patent/WO2017158039A1/en active Application Filing
- 2017-03-15 US US16/085,025 patent/US11534483B2/en active Active
- 2017-03-15 DK DK17710307.4T patent/DK3429616T3/da active
- 2017-03-15 PT PT177103074T patent/PT3429616T/pt unknown
- 2017-03-15 EA EA201891932A patent/EA201891932A1/ru unknown
- 2017-03-15 MX MX2018010710A patent/MX2018010710A/es unknown
- 2017-03-15 HU HUE17710307A patent/HUE055935T2/hu unknown
-
2018
- 2018-09-13 IL IL261779A patent/IL261779B/en unknown
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2021
- 2021-10-14 CY CY20211100888T patent/CY1124760T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS62442B1 (sr) | 2021-11-30 |
| US20190328853A1 (en) | 2019-10-31 |
| CN109414486A (zh) | 2019-03-01 |
| CY1124760T1 (el) | 2022-07-22 |
| MX2018010710A (es) | 2019-01-14 |
| EP3429616B1 (en) | 2021-08-04 |
| DK3429616T3 (da) | 2021-10-18 |
| CA3017654A1 (en) | 2017-09-21 |
| IL261779B (en) | 2021-12-01 |
| PL3429616T3 (pl) | 2022-01-03 |
| SI3429616T1 (sl) | 2021-12-31 |
| CA3017654C (en) | 2023-07-25 |
| AU2017234985B2 (en) | 2023-10-12 |
| EA201891932A1 (ru) | 2019-03-29 |
| CN109414486B (zh) | 2023-06-06 |
| PT3429616T (pt) | 2021-09-17 |
| IL261779A (en) | 2018-10-31 |
| LT3429616T (lt) | 2021-10-25 |
| EP3429616A1 (en) | 2019-01-23 |
| AU2017234985A1 (en) | 2018-08-16 |
| HUE055935T2 (hu) | 2022-01-28 |
| ES2894370T3 (es) | 2022-02-14 |
| US11534483B2 (en) | 2022-12-27 |
| WO2017158039A1 (en) | 2017-09-21 |
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