HRP20200821T1 - Novi procesi za pripremu vemurafeniba - Google Patents

Novi procesi za pripremu vemurafeniba Download PDF

Info

Publication number
HRP20200821T1
HRP20200821T1 HRP20200821TT HRP20200821T HRP20200821T1 HR P20200821 T1 HRP20200821 T1 HR P20200821T1 HR P20200821T T HRP20200821T T HR P20200821TT HR P20200821 T HRP20200821 T HR P20200821T HR P20200821 T1 HRP20200821 T1 HR P20200821T1
Authority
HR
Croatia
Prior art keywords
formula
compound
image
process according
reaction
Prior art date
Application number
HRP20200821TT
Other languages
English (en)
Croatian (hr)
Inventor
Antti KATAJA
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of HRP20200821T1 publication Critical patent/HRP20200821T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP20200821TT 2016-07-01 2017-06-30 Novi procesi za pripremu vemurafeniba HRP20200821T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI20165557 2016-07-01
FI20165778 2016-10-12
EP17745368.5A EP3478684B1 (en) 2016-07-01 2017-06-30 New processes for the preparation of vemurafenib
PCT/FI2017/000012 WO2018002415A1 (en) 2016-07-01 2017-06-30 New processes for the preparation of vemurafenib

Publications (1)

Publication Number Publication Date
HRP20200821T1 true HRP20200821T1 (hr) 2020-08-07

Family

ID=59416718

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20200821TT HRP20200821T1 (hr) 2016-07-01 2017-06-30 Novi procesi za pripremu vemurafeniba

Country Status (10)

Country Link
US (1) US10407427B2 (enExample)
EP (1) EP3478684B1 (enExample)
JP (1) JP6911062B2 (enExample)
CA (1) CA3029361A1 (enExample)
ES (1) ES2802476T3 (enExample)
HR (1) HRP20200821T1 (enExample)
HU (1) HUE049682T2 (enExample)
PL (1) PL3478684T3 (enExample)
RS (1) RS60451B1 (enExample)
WO (1) WO2018002415A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
DK3860598T3 (da) 2018-10-03 2023-10-16 Jyvaeskylaen Yliopisto Vemurafenib og salte heraf til anvendelse til behandling af enterovirusinfektioner

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303759B1 (it) * 1998-11-17 2001-02-23 Dompe Spa Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.
PT1893612E (pt) 2005-06-22 2011-11-21 Plexxikon Inc Derivados de pirrolo [2,3-b]piridina como inibidores de proteína quinase
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
US8779150B2 (en) 2010-07-21 2014-07-15 Hoffmann-La Roche Inc. Processes for the manufacture of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1 H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide
EA028351B1 (ru) 2013-03-14 2017-11-30 Ратиофарм Гмбх Твердые формы гидрохлорида вемурафениба
WO2015075749A1 (en) 2013-11-22 2015-05-28 Laurus Labs Private Limited Novel processes for the preparation of vemurafenib
CZ2013943A3 (cs) 2013-11-27 2015-06-03 Zentiva, K.S. Krystalické formy vemurafenibu
US10414764B2 (en) 2014-11-29 2019-09-17 Shilpa Medicare Limited Substantially pure vemurafenib and its salts

Also Published As

Publication number Publication date
HUE049682T2 (hu) 2020-10-28
US20190194197A1 (en) 2019-06-27
JP2019522662A (ja) 2019-08-15
JP6911062B2 (ja) 2021-07-28
RS60451B1 (sr) 2020-07-31
CA3029361A1 (en) 2018-01-04
US10407427B2 (en) 2019-09-10
ES2802476T3 (es) 2021-01-19
WO2018002415A1 (en) 2018-01-04
EP3478684B1 (en) 2020-04-15
PL3478684T3 (pl) 2020-08-10
EP3478684A1 (en) 2019-05-08

Similar Documents

Publication Publication Date Title
ES2495815T3 (es) Proceso para la síntesis de lacosamida
HRP20200186T1 (hr) Radioaktivno obilježeni derivati 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]-pirazolo[1,5-a]pirimidin-3-karboksamid spojeva koji se koriste kao inhibitori atr kinaze, priprava navedenih spojeva i njihovi različiti čvrsti oblici
HRP20200821T1 (hr) Novi procesi za pripremu vemurafeniba
ES2567081T3 (es) Producción continua de sales cuaternarias
RU2019119584A (ru) Способ получения триазолопиридинового соединения
RU2011132912A (ru) Адаптируемое опорное устройство с шаговым относительным позиционированием
JP2019522662A5 (enExample)
MX377949B (es) Soluciones de sales de metal trialcalino de acidos aminocarboxilicos, su produccion y uso.
AR069759A1 (es) Proceso de intermediarios utiles en la preparacion de 5-(etil- dihidro-1-h-inden-2-il) 1h- imidazola
ES2723437T3 (es) Procesos y productos intermedios para la preparación de un inhibidor de PDE10
ECSP12012207A (es) Procedimiento para la preparación de 2-(ciclohexilmetil)-n-{2-[(2s)-1-metilpirrolidin-2-il]etil}-1,2,3,4-tetrahidroisoquinolin-7-sulfonamida
EA201491463A1 (ru) Способ получения соединения по новой реакции присоединения михаэля с применением воды или различных кислот в качестве добавки
MX2018004631A (es) Proceso industrial para la preparación de la sal de (e)-3-carboxiacrilato de (5s,10s)-10-bencil-16-metil-11,14,18-trio xo-15,17,19-trioxa-2,7,8-tritia-12-azahenicosan-5-aminio.
ES2658413T3 (es) Fase cristalina de (3S,3S') 4,4'-disulfanodiilbis(ácido 3-aminobutano 1-sulfónico) con L-lisina
MD4443B1 (ro) Procedeu de sinteză a 3,4-dimetoxibiciclo[4.2.0]octa-1,3,5-trien-7-carbonitrilului şi aplicarea lui în sinteza ivabradinei şi a sărurilor sale de adiţie cu un acid acceptabil farmaceutic
CU22996A3 (es) Método para obtener ácidos benzoicos 2-(n-fenilamino).
FR3011081B1 (fr) Procede d'estimation de la qualite de la vapeur d'eau generee dans une installation de production d'hydrocarbures, procede de qualification d'un generateur de vapeur d'eau
CN208625533U (zh) 一种防止滑脱的肥皂结构
RU2012128422A (ru) Способ получения 1-алкиниладамантанов
RU2013101109A (ru) Способ получения алкенилантрахинонов
Yoshimitsu Synthetic Studies of Tetrahydrofuran-containing Natural Products
TH132871A (th) ผลึกของอนุพันธ์ 6,7-ชนิดไม่อิ่มตัว-7-คาร์บาโมอิลมอร์ฟิแนนและวิธีการในการผลิตผลึกดังกล่าว
CN105215591A (zh) 一种散热器焊接定位卡板
TH1701005613A (th) สีย้อมอินทรีย์จากอนุพันธ์ของสารประกอบ n-((3,4-ไดไซยาโนไดเบนโซ[c,g]ฟีแนนทรีน-13-อิล)ออกซี)อัลเคโนอิก แอซิด สำหรับใช้เป็นโมเลกุลแสดงสัญญาณเพื่อการตรวจวัด และกรรมวิธีการสังเคราะห์สารประกอบดังกล่าว
TH183775S (th) ก้อนสบู่