HRP20200630T1 - Triazini, namijenjeni liječenju protozojskih bolesti - Google Patents
Triazini, namijenjeni liječenju protozojskih bolesti Download PDFInfo
- Publication number
- HRP20200630T1 HRP20200630T1 HRP20200630TT HRP20200630T HRP20200630T1 HR P20200630 T1 HRP20200630 T1 HR P20200630T1 HR P20200630T T HRP20200630T T HR P20200630TT HR P20200630 T HRP20200630 T HR P20200630T HR P20200630 T1 HRP20200630 T1 HR P20200630T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation
- pig
- intended
- administered
- accordance
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000003918 triazines Chemical class 0.000 title 1
- OCINXEZVIIVXFU-UHFFFAOYSA-N 1-methyl-3-[3-methyl-4-[4-(trifluoromethylthio)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione Chemical compound CC1=CC(N2C(N(C)C(=O)NC2=O)=O)=CC=C1OC1=CC=C(SC(F)(F)F)C=C1 OCINXEZVIIVXFU-UHFFFAOYSA-N 0.000 claims 3
- 238000010255 intramuscular injection Methods 0.000 claims 3
- 239000007927 intramuscular injection Substances 0.000 claims 3
- 229960000898 toltrazuril Drugs 0.000 claims 3
- 208000003495 Coccidiosis Diseases 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 206010023076 Isosporiasis Diseases 0.000 claims 2
- 150000004698 iron complex Chemical class 0.000 claims 2
- 229910021519 iron(III) oxide-hydroxide Inorganic materials 0.000 claims 2
- WSHYKIAQCMIPTB-UHFFFAOYSA-M potassium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate Chemical compound [K+].[O-]C=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 WSHYKIAQCMIPTB-UHFFFAOYSA-M 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 241000282887 Suidae Species 0.000 claims 1
- 230000037396 body weight Effects 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Dispersion Chemistry (AREA)
Claims (7)
1. Pripravak, koji sadrži toltrazuril i kompleks željeza, koji je vodena koloidna otopina β-feri oksihidroksida i dekstranglukoheptonske kiseline, naznačen time što je namijenjen upotrebi u liječenju kokcidioze kod prasadi, gdje se navedeni pripravak primjenjuje intramuskularnom injekcijom.
2. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 1, naznačen time što se pripravak primjenjuje jednom injekcijom na prasetu.
3. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 1 ili 2, naznačen time što se pripravak primjenjuje intramuskularnom injekcijom u vrat ili iza uha praseta.
4. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 1, naznačen time što sadrži između 1 i 60 mg toltrazurila po kg tjelesne težine.
5. Pripravak namijenjen upotrebi u skladu s bilo kojim od patentnih zahtjeva 1 do 4, naznačen time što je formulacija suspenzija.
6. Pripravak namijenjen upotrebi u preventivnom liječenju praseta od kokcidioze, naznačen time što je pripravak suspenzija koja sadrži između 1 i 60 mg toltrazurila i kompleksa željeza, koji je vodena koloidna otopina beta-feri oksihidroksida i dekstranglukoheptonske kiseline, te što se pripravak primjenjuje intramuskularnom injekcijom na navedenom prasetu.
7. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 1 ili 6, naznačen time što je prase novorođeno do 10 dana staro prase.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12306546.8A EP2740469A1 (en) | 2012-12-07 | 2012-12-07 | New treatments with triazines |
EP13802596.0A EP2928454B1 (en) | 2012-12-07 | 2013-12-06 | Triazines for treating protozoan diseases |
PCT/EP2013/075755 WO2014086958A1 (en) | 2012-12-07 | 2013-12-06 | New treatments with triazines |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20200630T1 true HRP20200630T1 (hr) | 2020-07-10 |
Family
ID=47351540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20200630TT HRP20200630T1 (hr) | 2012-12-07 | 2020-04-15 | Triazini, namijenjeni liječenju protozojskih bolesti |
Country Status (23)
Country | Link |
---|---|
US (1) | US9877969B2 (hr) |
EP (3) | EP2740469A1 (hr) |
JP (1) | JP6125034B2 (hr) |
KR (1) | KR102253497B1 (hr) |
CN (3) | CN113144202A (hr) |
AU (1) | AU2013353982B2 (hr) |
BR (3) | BR122021005311B1 (hr) |
CA (1) | CA2892886C (hr) |
CL (1) | CL2015001563A1 (hr) |
CY (1) | CY1123190T1 (hr) |
DK (1) | DK2928454T3 (hr) |
ES (1) | ES2778950T3 (hr) |
FR (1) | FR20C1044I2 (hr) |
HR (1) | HRP20200630T1 (hr) |
HU (2) | HUE049950T2 (hr) |
MX (1) | MX2015007128A (hr) |
NL (1) | NL301064I2 (hr) |
PH (1) | PH12015501220B1 (hr) |
PL (1) | PL2928454T3 (hr) |
PT (1) | PT2928454T (hr) |
RU (1) | RU2696265C2 (hr) |
SI (1) | SI2928454T1 (hr) |
WO (1) | WO2014086958A1 (hr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007025908A1 (de) | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
EP2740470A1 (en) * | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Treatment of Coccidiosis with intramuscular triazine composition |
EP2740492A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Triazine formulations with a second active ingredient and surfactant(s) |
EP2740469A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | New treatments with triazines |
EP3578181A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies |
EP3578182A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulations containing triazinones and iron with a low amount of free iron ions |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1183940A (en) | 1966-10-22 | 1970-03-11 | Fisons Pharmaceuticals Ltd | Ferric Hydroxide Complexes |
DE2718799A1 (de) | 1977-04-27 | 1978-11-09 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazin- derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und wachstumsfoerderer |
US4493826A (en) * | 1982-01-25 | 1985-01-15 | Schering Corporation | Gentamicin-gleptoferron compositions |
US5219853A (en) | 1983-01-12 | 1993-06-15 | Bayer Aktiengesellschaft | Agent for coccidiosis |
DE3300793A1 (de) | 1983-01-12 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Coccidiosemittel |
DE3516632A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 1,3,5-triazintrionen |
JPH0776524A (ja) * | 1993-07-13 | 1995-03-20 | Takeda Chem Ind Ltd | 動物用抗貧血剤 |
DE19603954C2 (de) | 1996-02-05 | 2003-04-17 | Wagon Automotive Gmbh | Prallträger für ein Kraftfahrzeug |
DE19603984A1 (de) | 1996-02-05 | 1997-08-07 | Bayer Ag | Granulate von Triazinen |
DE19824483A1 (de) | 1998-06-02 | 1999-12-09 | Bayer Ag | Halbfeste wäßrige Zubereitungen für orale Applikation von Toltrazuril-Sulfon |
BR9914385A (pt) * | 1998-10-08 | 2001-07-17 | New Ace Res Company | Composição útil para o tratamento e prevenção de infecções protozoárias no homem e em animais, e, método de tratamento de uma infecção protozoária no homem e em animais |
WO2001026660A1 (en) | 1999-10-08 | 2001-04-19 | New Ace Research Company | Novel compositions and methods for prevention and treatment of protozoal disease |
DE10040174A1 (de) * | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfonen zur Bekämpfung von Coccidiosen |
DK2532378T3 (en) | 2004-12-01 | 2016-07-25 | Acushot Inc | needleless injector |
AU2007257173B2 (en) | 2006-06-07 | 2013-03-14 | Acushot Inc. | Charging mechanism for a needle-free injector |
DE102006038292A1 (de) | 2006-08-16 | 2008-02-21 | Bayer Healthcare Ag | Transdermale Anwendung von Triazinen zur Bekämpfung von Coccidien-Infektionen |
DE102007025908A1 (de) * | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
US20110288521A1 (en) | 2008-03-07 | 2011-11-24 | Pharma Jet ,Inc. | Intradermal injector and uses thereof |
SI22751A (sl) | 2008-04-03 | 2009-10-31 | Krka, D.D., Novo Mesto | Toltrazuril z izboljĺ animi lastnostmi za raztapljanje |
FR2946882B1 (fr) | 2009-06-18 | 2011-08-26 | Ceva Sante Animale | Suspension veterinaire gelifiee de fer |
CN101947201B (zh) | 2010-09-08 | 2011-12-28 | 洛阳惠中兽药有限公司 | 兽药纳米混悬剂及其制备方法与应用 |
CN102512366A (zh) | 2011-12-28 | 2012-06-27 | 广州市和生堂动物药业有限公司 | 妥曲珠利悬浮乳剂及其制备方法 |
CN102743334A (zh) | 2012-07-30 | 2012-10-24 | 郑州后羿制药有限公司 | 一种妥曲珠利注射剂及其制备方法 |
EP2740470A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Treatment of Coccidiosis with intramuscular triazine composition |
EP2740492A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Triazine formulations with a second active ingredient and surfactant(s) |
EP2740469A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | New treatments with triazines |
EP3578181A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies |
-
2012
- 2012-12-07 EP EP12306546.8A patent/EP2740469A1/en not_active Withdrawn
-
2013
- 2013-12-06 SI SI201331711T patent/SI2928454T1/sl unknown
- 2013-12-06 EP EP20158340.8A patent/EP3721869A1/en active Pending
- 2013-12-06 CN CN202110239548.1A patent/CN113144202A/zh active Pending
- 2013-12-06 RU RU2015127025A patent/RU2696265C2/ru active
- 2013-12-06 BR BR122021005311-1A patent/BR122021005311B1/pt active IP Right Grant
- 2013-12-06 DK DK13802596.0T patent/DK2928454T3/da active
- 2013-12-06 CN CN202011031157.2A patent/CN112370454A/zh active Pending
- 2013-12-06 JP JP2015546022A patent/JP6125034B2/ja active Active
- 2013-12-06 CN CN201380063619.0A patent/CN104981233A/zh active Pending
- 2013-12-06 WO PCT/EP2013/075755 patent/WO2014086958A1/en active Application Filing
- 2013-12-06 BR BR122021005310-3A patent/BR122021005310B1/pt active IP Right Grant
- 2013-12-06 PT PT138025960T patent/PT2928454T/pt unknown
- 2013-12-06 AU AU2013353982A patent/AU2013353982B2/en active Active
- 2013-12-06 ES ES13802596T patent/ES2778950T3/es active Active
- 2013-12-06 EP EP13802596.0A patent/EP2928454B1/en active Active
- 2013-12-06 CA CA2892886A patent/CA2892886C/en active Active
- 2013-12-06 KR KR1020157018136A patent/KR102253497B1/ko active IP Right Grant
- 2013-12-06 PL PL13802596T patent/PL2928454T3/pl unknown
- 2013-12-06 US US14/650,046 patent/US9877969B2/en active Active
- 2013-12-06 BR BR112015013182A patent/BR112015013182A2/pt not_active Application Discontinuation
- 2013-12-06 MX MX2015007128A patent/MX2015007128A/es unknown
- 2013-12-06 HU HUE13802596A patent/HUE049950T2/hu unknown
-
2015
- 2015-06-01 PH PH12015501220A patent/PH12015501220B1/en unknown
- 2015-06-05 CL CL2015001563A patent/CL2015001563A1/es unknown
-
2020
- 2020-04-15 HR HRP20200630TT patent/HRP20200630T1/hr unknown
- 2020-04-16 CY CY20201100364T patent/CY1123190T1/el unknown
- 2020-09-16 FR FR20C1044C patent/FR20C1044I2/fr active Active
- 2020-09-16 NL NL301064C patent/NL301064I2/nl unknown
- 2020-09-16 HU HUS2000037C patent/HUS2000037I1/hu unknown
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