HRP20200380T1 - Pripravak koji sadrži ester alfa-tokoferola za prevenciju i liječenje alergijskog rinitisa - Google Patents
Pripravak koji sadrži ester alfa-tokoferola za prevenciju i liječenje alergijskog rinitisa Download PDFInfo
- Publication number
- HRP20200380T1 HRP20200380T1 HRP20200380TT HRP20200380T HRP20200380T1 HR P20200380 T1 HRP20200380 T1 HR P20200380T1 HR P20200380T T HRP20200380T T HR P20200380TT HR P20200380 T HRP20200380 T HR P20200380T HR P20200380 T1 HRP20200380 T1 HR P20200380T1
- Authority
- HR
- Croatia
- Prior art keywords
- alpha
- preparation
- hydrogenated
- use according
- tocopherol
- Prior art date
Links
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title claims 8
- 229940087168 alpha tocopherol Drugs 0.000 title claims 6
- 229960000984 tocofersolan Drugs 0.000 title claims 6
- 239000002076 α-tocopherol Substances 0.000 title claims 6
- 235000004835 α-tocopherol Nutrition 0.000 title claims 6
- 239000000203 mixture Substances 0.000 title claims 3
- 206010039085 Rhinitis allergic Diseases 0.000 title claims 2
- 201000010105 allergic rhinitis Diseases 0.000 title claims 2
- 150000002148 esters Chemical class 0.000 title claims 2
- 230000002265 prevention Effects 0.000 title claims 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims 4
- -1 alpha-tocopherol ester Chemical class 0.000 claims 4
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims 4
- 239000003921 oil Substances 0.000 claims 4
- 235000019198 oils Nutrition 0.000 claims 4
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims 2
- 244000056974 Adansonia digitata Species 0.000 claims 2
- 235000003320 Adansonia digitata Nutrition 0.000 claims 2
- 244000060011 Cocos nucifera Species 0.000 claims 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims 2
- 240000007817 Olea europaea Species 0.000 claims 2
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims 2
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 claims 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 claims 2
- 229920000098 polyolefin Polymers 0.000 claims 2
- 229940031439 squalene Drugs 0.000 claims 2
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 2
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 claims 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-M 9-cis,12-cis-Octadecadienoate Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O OYHQOLUKZRVURQ-HZJYTTRNSA-M 0.000 claims 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 claims 1
- 229940100554 isononyl isononanoate Drugs 0.000 claims 1
- 229940049918 linoleate Drugs 0.000 claims 1
- FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 claims 1
- 235000020238 sunflower seed Nutrition 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 239000008158 vegetable oil Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Claims (7)
1. Pripravak za vanjsku primjenu, za upotrebu u prevenciji ili liječenju alergijskog rinitisa, koja se sastoji od
estera alfa-tokoferola izabranog iz grupe koja se sastoji od alfa-tokoferil acetata, n-propionata i linoleata, i
uljnog nosača izabranog iz grupe koja se sastoji od hidrogeniranog poliizobutena, hidrogeniranog polidecena,
mješavina hidrogeniranog poliizobutena i/ili hidrogeniranog polidecena sa hidrogeniranim poliolefinima, konkretno hidrogeniranim C6-C14 hidrogeniranim poliolefinima,
triglicerida kaprilne/kaprinske kiseline, biljnog ulja, ulja Adansonia digitata, ulja sjemena Adansonia digitata, kokosovog kaprilata/kaprata, skvalena masline, skvalena masline, ulja sjemena suncokreta (Heliantus annus), kokosovog kaprilata, izononil izononanoata, ciklopentasiloksana, i njihovih mješavina.
2. Pripravak za upotrebu prema patentnom zahtjevu 1, naznačen time, što navedeni pripravak sadrži 3% do 80% po težini navedenog estera alfa-tokoferola u odnosu na ukupnu težinu pripravka.
3. Pripravak za upotrebu prema patentnom zahtjevu 1, naznačen time, što navedeni pripravak sadrži 5% do 40%, poželjno 10% do 30% po težini navedenog estera alfa-tokoferola u odnosu na ukupnu težinu pripravka.
4. Pripravak za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 3, naznačen time, što je navedeni ester alfa-tokoferola alfa-tokoferil acetat.
5. Pripravak za upotrebu prema bilo kojem od patentnih zahtjeva 1 do 4, naznačen time, što se navedeni uljni nosač sastoji od hidrogeniranog polidecena.
6. Pripravak za upotrebu prema patentnom zahtjevu 5, naznačen time, što je navedeni ester alfa-tokoferola alfa-tokoferil acetat.
7. Pripravak za upotrebu prema patentnom zahtjevu 6, koji se sastoji od 10-30% alfa-tokoferil acetata i 70-90% hidrogeniranog polidecena.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI20141332 | 2014-07-22 | ||
| EP15720286.2A EP3171873B1 (en) | 2014-07-22 | 2015-04-17 | Composition comprising an ester of alpha-tocopherol for prevention and treatment of allergic rhinitis |
| PCT/EP2015/058368 WO2016012110A1 (en) | 2014-07-22 | 2015-04-17 | Composition comprising an ester of alpha-tocopherol for prevention and treatment of allergic rhinitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20200380T1 true HRP20200380T1 (hr) | 2020-08-07 |
Family
ID=51589387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200380TT HRP20200380T1 (hr) | 2014-07-22 | 2020-03-06 | Pripravak koji sadrži ester alfa-tokoferola za prevenciju i liječenje alergijskog rinitisa |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20170165226A1 (hr) |
| EP (1) | EP3171873B1 (hr) |
| CN (1) | CN106659709A (hr) |
| AR (1) | AR101274A1 (hr) |
| AU (1) | AU2015294663B2 (hr) |
| BR (1) | BR112017001116A8 (hr) |
| CA (1) | CA2955664C (hr) |
| CL (1) | CL2017000058A1 (hr) |
| CO (1) | CO2017000550A2 (hr) |
| CY (1) | CY1122823T1 (hr) |
| DE (1) | DE202014106007U1 (hr) |
| DK (1) | DK3171873T3 (hr) |
| EA (1) | EA201692486A1 (hr) |
| ES (1) | ES2779525T3 (hr) |
| HR (1) | HRP20200380T1 (hr) |
| HU (1) | HUE049588T2 (hr) |
| LT (1) | LT3171873T (hr) |
| MX (1) | MX369991B (hr) |
| PE (1) | PE20170437A1 (hr) |
| PL (1) | PL3171873T3 (hr) |
| PT (1) | PT3171873T (hr) |
| RS (1) | RS60103B1 (hr) |
| SI (1) | SI3171873T1 (hr) |
| WO (1) | WO2016012110A1 (hr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6992057B2 (ja) | 2016-06-10 | 2022-01-13 | クラリティ コスメティックス インコーポレイテッド | 非面皰形成性の毛髪および頭皮ケア製剤ならびにその使用方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4269835A (en) * | 1979-12-13 | 1981-05-26 | Whittle Barry J | Nasal composition for relieving nasal distress |
| US4364945A (en) * | 1979-12-13 | 1982-12-21 | Whittle Barry J | Nasal composition for relieving nasal distress |
| US20100055152A1 (en) * | 2008-08-26 | 2010-03-04 | Trutek Corporation | Antihistamine and antihistamine-like nasal application, products, and method |
| DE4327089A1 (de) * | 1993-08-12 | 1995-02-16 | Roshdy Ismail | Mittel zur Behandlung von allergischen Erkrankungen der Atemwege |
| IT1282778B1 (it) * | 1996-05-31 | 1998-03-31 | Giorgio Panin | Vitamina "e" acetato quale prodotto per applicazione topica |
| ITMI981586A1 (it) * | 1998-07-10 | 2000-01-10 | Giorgio Panin | Vitamina e e suoi esteri per l'uso nel trattamento topico di patologie delle mucose |
| JP2003128552A (ja) * | 2001-08-16 | 2003-05-08 | Rohto Pharmaceut Co Ltd | 粘膜適用組成物 |
| US20060198904A1 (en) | 2002-11-20 | 2006-09-07 | Istvan Boldogh | Methods for inhibiting allergic inflammation and other responses initiated by pollens, molds, and other non-animal derived allergens |
| JP2008266255A (ja) * | 2007-04-24 | 2008-11-06 | Project M:Kk | アレルギー性疾患を予防および／または治療するための組成物 |
| US20100076072A1 (en) | 2008-07-25 | 2010-03-25 | Northwestern University | Compositions and methods of vitamin e administration |
| IT1393056B1 (it) * | 2008-09-22 | 2012-04-11 | Bio Lo Ga Srl | Uso di vitamina e o suoi derivati per il controllo di artropodi |
| ITMI20090480A1 (it) * | 2009-03-27 | 2010-09-28 | Bio Lo Ga Srl | Supporto tessile imbevuto di una composizione detergente/idratante |
| CN103717235A (zh) * | 2011-06-24 | 2014-04-09 | 埃皮托吉尼西斯有限公司 | 作为抗原特异性免疫调节剂的包含选择的载体、维生素、单宁和类黄酮的组合的药物组合物 |
-
2014
- 2014-12-12 DE DE202014106007.3U patent/DE202014106007U1/de not_active Expired - Lifetime
-
2015
- 2015-04-17 HU HUE15720286A patent/HUE049588T2/hu unknown
- 2015-04-17 CN CN201580039442.XA patent/CN106659709A/zh active Pending
- 2015-04-17 PT PT157202862T patent/PT3171873T/pt unknown
- 2015-04-17 LT LTEP15720286.2T patent/LT3171873T/lt unknown
- 2015-04-17 WO PCT/EP2015/058368 patent/WO2016012110A1/en active Application Filing
- 2015-04-17 DK DK15720286.2T patent/DK3171873T3/da active
- 2015-04-17 US US15/325,890 patent/US20170165226A1/en not_active Abandoned
- 2015-04-17 CA CA2955664A patent/CA2955664C/en active Active
- 2015-04-17 AU AU2015294663A patent/AU2015294663B2/en active Active
- 2015-04-17 ES ES15720286T patent/ES2779525T3/es active Active
- 2015-04-17 MX MX2017000906A patent/MX369991B/es active IP Right Grant
- 2015-04-17 RS RS20200263A patent/RS60103B1/sr unknown
- 2015-04-17 PL PL15720286T patent/PL3171873T3/pl unknown
- 2015-04-17 EA EA201692486A patent/EA201692486A1/ru unknown
- 2015-04-17 EP EP15720286.2A patent/EP3171873B1/en active Active
- 2015-04-17 PE PE2017000002A patent/PE20170437A1/es unknown
- 2015-04-17 SI SI201531114T patent/SI3171873T1/sl unknown
- 2015-04-17 BR BR112017001116A patent/BR112017001116A8/pt not_active Application Discontinuation
- 2015-07-22 AR ARP150102322A patent/AR101274A1/es unknown
-
2017
- 2017-01-10 CL CL2017000058A patent/CL2017000058A1/es unknown
- 2017-01-23 CO CONC2017/0000550A patent/CO2017000550A2/es unknown
-
2020
- 2020-03-06 HR HRP20200380TT patent/HRP20200380T1/hr unknown
- 2020-03-16 CY CY20201100225T patent/CY1122823T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2955664C (en) | 2022-09-06 |
| PE20170437A1 (es) | 2017-04-22 |
| CA2955664A1 (en) | 2016-01-28 |
| CL2017000058A1 (es) | 2017-08-11 |
| SI3171873T1 (sl) | 2020-07-31 |
| US20170165226A1 (en) | 2017-06-15 |
| PL3171873T3 (pl) | 2020-07-13 |
| LT3171873T (lt) | 2020-04-10 |
| EP3171873A1 (en) | 2017-05-31 |
| WO2016012110A1 (en) | 2016-01-28 |
| MX2017000906A (es) | 2017-05-12 |
| AU2015294663B2 (en) | 2019-11-21 |
| ES2779525T3 (es) | 2020-08-18 |
| HUE049588T2 (hu) | 2020-10-28 |
| EA201692486A1 (ru) | 2017-07-31 |
| CY1122823T1 (el) | 2021-05-05 |
| RS60103B1 (sr) | 2020-05-29 |
| AR101274A1 (es) | 2016-12-07 |
| AU2015294663A1 (en) | 2017-01-19 |
| DK3171873T3 (da) | 2020-03-16 |
| BR112017001116A2 (pt) | 2018-01-23 |
| DE202014106007U1 (de) | 2015-07-23 |
| MX369991B (es) | 2019-11-27 |
| CN106659709A (zh) | 2017-05-10 |
| PT3171873T (pt) | 2020-02-25 |
| CO2017000550A2 (es) | 2017-03-31 |
| EP3171873B1 (en) | 2019-12-25 |
| BR112017001116A8 (pt) | 2022-07-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2019014980A (es) | 3-fenilisoxazolin-5-carboxamidas de acidos y esteres tetrahidro y dihidrofuranocarboxilicos con efecto herbicida. | |
| EA201790978A1 (ru) | Способы и композиции, относящиеся к синтетическим наноносителям с рапамицином в стабильном пересыщенном состоянии | |
| BR112015016082A2 (pt) | curativo indicador de umidade | |
| PH12014501411B1 (en) | Fabric softener active composition | |
| EA201990337A1 (ru) | Композиция для местного применения с противогрибковой активностью | |
| HRP20191989T1 (hr) | Farmaceutski pripravak za uporabu u povećanju trofizma sluznice nosa | |
| BR112015023190A2 (pt) | regulação de câncer com o uso de compostos e/ou dieta naturais | |
| FR3024037B1 (fr) | Ingredient actif cosmetique ou dermatologique comprenant un melange d'acides dicarboxyliques gras insatures, compositions le comprenant et utilisations cosmetiques ou dermatologiques | |
| EP2997958A3 (de) | Formulierung enthaltend flüssige esterquats und/oder imidazoliniumsalze und polymerverdicker | |
| AR094407A1 (es) | Protección de ácido 4-amino-3-cloro-6-(4-cloro-2-flúor-3-metoxifenil)piridina-2-carboxílico y los derivados del mismo en los cultivos de cereales | |
| CY1123942T1 (el) | Συνθεσεις ωμεγα-3 λιπαρων οξεων για τη θεραπεια ασθενειων που επιφερουν βλαβη στο νευρικο συστημα | |
| DOP2017000058A (es) | Derivados de tetrahidroquinolina como inhibidores del bromodominio | |
| HRP20200380T1 (hr) | Pripravak koji sadrži ester alfa-tokoferola za prevenciju i liječenje alergijskog rinitisa | |
| JP2016519101A5 (hr) | ||
| MY183624A (en) | Transparent sunscreen compositions and use thereof | |
| WO2014164648A3 (en) | Solid state forms of a quinazoline derivative and its use as a braf inhibitor | |
| CO7141473A2 (es) | Vehículos de liberación de composiciones pesticidas | |
| CL2017001579A1 (es) | Copolímeros de polidialilamina reticulados para el tratamiento de la diabetes de tipo 2 | |
| MX2021001790A (es) | Composiciones solidas de trigliceridos y usos de estas. | |
| FR3007652B1 (fr) | Composition comprenant de l'acide docosahexaenoique et du pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate | |
| UY36227A (es) | Composición para uso en la prevención y tratamiento de rinitis alérgica | |
| WO2015123480A3 (en) | Compositions and methods for the prevention and/or treatment of schistosomiasis | |
| MY178089A (en) | Glyceride composition | |
| BR112016024753A2 (pt) | produto absorvente | |
| CL2018001806A1 (es) | Composiciones cosméticas que comprenden una combinación sinérgica de partículas absorbentes y adsorbentes de sudor y usos de las mismas |