HRP20190907T1 - Imunogeni pripravak koji sadrži polipeptide iz panton-valentin leukocidina (pvl) - Google Patents
Imunogeni pripravak koji sadrži polipeptide iz panton-valentin leukocidina (pvl) Download PDFInfo
- Publication number
- HRP20190907T1 HRP20190907T1 HRP20190907TT HRP20190907T HRP20190907T1 HR P20190907 T1 HRP20190907 T1 HR P20190907T1 HR P20190907T T HRP20190907T T HR P20190907TT HR P20190907 T HRP20190907 T HR P20190907T HR P20190907 T1 HRP20190907 T1 HR P20190907T1
- Authority
- HR
- Croatia
- Prior art keywords
- mutant
- leukocidin
- subunit
- tag
- seq
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161566234P | 2011-12-02 | 2011-12-02 | |
| PCT/US2012/067483 WO2013082558A1 (en) | 2011-12-02 | 2012-11-30 | Immunogenic composition comprising panton-valentine leukocidin (pvl) derived polypeptides |
| EP12854165.3A EP2785368B1 (en) | 2011-12-02 | 2012-11-30 | Immunogenic composition comprising panton-valentine leukocidin (pvl) derived polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20190907T1 true HRP20190907T1 (hr) | 2019-07-12 |
Family
ID=48536149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20190907TT HRP20190907T1 (hr) | 2011-12-02 | 2012-11-30 | Imunogeni pripravak koji sadrži polipeptide iz panton-valentin leukocidina (pvl) |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10023848B2 (enExample) |
| EP (1) | EP2785368B1 (enExample) |
| JP (1) | JP6325452B2 (enExample) |
| KR (1) | KR101999299B1 (enExample) |
| AU (1) | AU2012345645B2 (enExample) |
| CA (1) | CA2857666C (enExample) |
| DK (1) | DK2785368T3 (enExample) |
| ES (1) | ES2728445T3 (enExample) |
| HR (1) | HRP20190907T1 (enExample) |
| LT (1) | LT2785368T (enExample) |
| RS (1) | RS58919B1 (enExample) |
| SI (1) | SI2785368T1 (enExample) |
| WO (1) | WO2013082558A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2857666C (en) | 2011-12-02 | 2020-08-11 | Integrated Biotherapeutics, Inc. | Immunogenic composition comprising panton-valentine leukocidin (pvl) derived polypeptides |
| CN110420316A (zh) | 2013-06-18 | 2019-11-08 | 纽约大学 | 参与金黄色葡萄球菌杀白细胞素的细胞毒性的细胞因素：新型治疗靶点 |
| CA2916231C (en) * | 2013-06-19 | 2024-02-06 | Integrated Biotherapeutics, Inc. | Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof |
| US9149522B2 (en) | 2013-09-25 | 2015-10-06 | Sequoia Sciences, Inc. | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| US9504743B2 (en) | 2013-09-25 | 2016-11-29 | Sequoia Sciences, Inc | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| US20150086592A1 (en) | 2013-09-25 | 2015-03-26 | Sequoia Sciences, Inc | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| US9149521B2 (en) | 2013-09-25 | 2015-10-06 | Sequoia Sciences, Inc. | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| CN105873946A (zh) * | 2013-10-17 | 2016-08-17 | 阿尔萨尼斯生物科学有限责任公司 | 交叉反应性金黄色葡萄球菌抗体序列 |
| JP6620817B2 (ja) * | 2015-08-10 | 2019-12-18 | 株式会社微生物化学研究所 | 黄色ブドウ球菌不活化菌体とロイコシジンを混合したワクチン |
| CN107224575B (zh) * | 2017-03-06 | 2018-11-09 | 浙江海隆生物科技有限公司 | 奶牛金黄色葡萄球菌乳房炎亚单位疫苗的组合物及其制备方法和应用 |
| MX2020001046A (es) | 2017-07-27 | 2020-08-06 | Integrated Biotherapeutic Vaccines Inc | Composicion inmunogenica que comprende un peptido de fusion derivado de toxoides de superantigenos. |
| WO2025085539A1 (en) * | 2023-10-16 | 2025-04-24 | The Trustees Of Columbia University In The City Of New York | Engineered bacteria for cellular barrier maintenance and protection |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US20100158871A1 (en) | 1999-08-30 | 2010-06-24 | David Stephen Terman | Sickled erythrocytes with antitumor molecules induce tumoricidal effects |
| US20050008633A1 (en) | 2003-05-19 | 2005-01-13 | Advanced Inhalation Research Inc. | Chemical and physical modulators of bioavailability of inhaled compositions |
| MX2007015758A (es) * | 2005-06-13 | 2008-02-22 | Nabi Biopharmaceuticals | Uso de leucocidina de panton-valentine para tratar y prevenir infecciones por estafilococos. |
| US7754225B2 (en) | 2006-07-20 | 2010-07-13 | Glaxosmithkline Biologicals S.A. | Method of protecting against staphylococcal infection |
| EP2388593A3 (fr) * | 2006-10-18 | 2012-01-18 | bioMérieux | Procédé de diagnostic in vitro des Staphylococcus aureus producteurs de PVL |
| CA2857666C (en) | 2011-12-02 | 2020-08-11 | Integrated Biotherapeutics, Inc. | Immunogenic composition comprising panton-valentine leukocidin (pvl) derived polypeptides |
-
2012
- 2012-11-30 CA CA2857666A patent/CA2857666C/en active Active
- 2012-11-30 RS RS20190664A patent/RS58919B1/sr unknown
- 2012-11-30 ES ES12854165T patent/ES2728445T3/es active Active
- 2012-11-30 US US14/362,298 patent/US10023848B2/en active Active
- 2012-11-30 JP JP2014544964A patent/JP6325452B2/ja active Active
- 2012-11-30 AU AU2012345645A patent/AU2012345645B2/en active Active
- 2012-11-30 DK DK12854165.3T patent/DK2785368T3/da active
- 2012-11-30 SI SI201231603T patent/SI2785368T1/sl unknown
- 2012-11-30 WO PCT/US2012/067483 patent/WO2013082558A1/en not_active Ceased
- 2012-11-30 LT LTEP12854165.3T patent/LT2785368T/lt unknown
- 2012-11-30 HR HRP20190907TT patent/HRP20190907T1/hr unknown
- 2012-11-30 EP EP12854165.3A patent/EP2785368B1/en active Active
- 2012-11-30 KR KR1020147018356A patent/KR101999299B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2785368A1 (en) | 2014-10-08 |
| EP2785368A4 (en) | 2015-12-30 |
| LT2785368T (lt) | 2019-06-10 |
| NZ626762A (en) | 2016-07-29 |
| EP2785368B1 (en) | 2019-03-13 |
| SI2785368T1 (sl) | 2019-08-30 |
| WO2013082558A1 (en) | 2013-06-06 |
| AU2012345645A1 (en) | 2014-06-26 |
| JP6325452B2 (ja) | 2018-05-16 |
| DK2785368T3 (da) | 2019-05-27 |
| ES2728445T3 (es) | 2019-10-24 |
| CA2857666C (en) | 2020-08-11 |
| US10023848B2 (en) | 2018-07-17 |
| US20140308291A1 (en) | 2014-10-16 |
| JP2015505831A (ja) | 2015-02-26 |
| KR20140117381A (ko) | 2014-10-07 |
| RS58919B1 (sr) | 2019-08-30 |
| AU2012345645B2 (en) | 2017-09-07 |
| KR101999299B1 (ko) | 2019-07-12 |
| CA2857666A1 (en) | 2013-06-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7094103B2 (ja) | インフルエンザウイルスワクチンおよびその使用 | |
| CA2710600C (en) | Recombinant rsv antigens | |
| US9492531B2 (en) | Recombinant RSV vaccines | |
| CA2952351C (en) | Influenza virus vaccines and uses thereof | |
| HRP20191902T1 (hr) | Antigeni virusa ljudske imunodeficijencije, vektori, pripravci, i postupci njihove upotrebe | |
| HRP20170094T1 (hr) | Imunogeni pripravak | |
| RU2017104529A (ru) | Композиции neisseria meningitidis и способы их применения | |
| Yadav et al. | Characterization of immune response elicited by the recombinant outer membrane protein OmpF of Aeromonas hydrophila, a potential vaccine candidate in murine model | |
| PE20140986A1 (es) | Proteinas de fusion y vacunas de combinacion que comprenden proteina e y pilina a de haemophilus influenzae | |
| JP2014507146A5 (enExample) | ||
| US20160122398A1 (en) | Recombinant rsv antigens | |
| WO2008127179A8 (en) | Fusion protein vaccine | |
| WO2015107363A3 (en) | Mycobacterial antigen composition | |
| KR101919002B1 (ko) | 구제역 바이러스의 가용성 다가 항원단백질 및 이의 용도 | |
| RU2015106916A (ru) | Полипептиды clostridium difficile в виде вакцины | |
| JP2015505831A5 (enExample) | ||
| WO2013158061A1 (en) | Recombinant mycobacterium encoding a heparin-binding hemagglutinin (hbha) fusion protein and uses thereof | |
| HRP20220064T1 (hr) | Zglobno modificirani fragmenti protutijela i postupci za pripravu | |
| CN107344969B (zh) | 一种纳米流感疫苗及构建方法和应用 | |
| Zhou et al. | A novel multivalent vaccine based on secretary antigen-delivery induces protective immunity against Vibrio anguillarum and Aeromonas hydrophila | |
| MX2023001219A (es) | Constructos de vacuna y sus usos contra infecciones causadas por staphylococcus. | |
| WO2013171661A3 (en) | Adjuvant formulations and methods | |
| HRP20191864T1 (hr) | Imunogeni pripravci protiv bakterije clostridium difficile | |
| TR201900695T4 (en) | HPV / CYAA-BASED CHEMICAL PROTEINS AND THEIR USE IN INDUCING IMMUNE RESPONSE AGAINST HPV INFECTION AND HPV-INDUCED DISASTER. | |
| KR101635673B1 (ko) | Ａ형 간염 바이러스 백신 소재 단백질 ｖｐ1-3ｎ 및 백신 조성물 |