DK2785368T3 - Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider - Google Patents

Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider Download PDF

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Publication number
DK2785368T3
DK2785368T3 DK12854165.3T DK12854165T DK2785368T3 DK 2785368 T3 DK2785368 T3 DK 2785368T3 DK 12854165 T DK12854165 T DK 12854165T DK 2785368 T3 DK2785368 T3 DK 2785368T3
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Denmark
Prior art keywords
panton
pvl
composition containing
immunogen composition
valentine leukocidin
Prior art date
Application number
DK12854165.3T
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English (en)
Inventor
Mohammad Javad Aman
Rajan Prasad Adhikari
Hatice Karauzum
Jawad Sarwar
Sergey Shulenin
Sathya Venkataramani
Kelly Lyn Warfield
Tam Luong Nguyen
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Integrated Biotherapeutics Inc
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Application filed by Integrated Biotherapeutics Inc filed Critical Integrated Biotherapeutics Inc
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Publication of DK2785368T3 publication Critical patent/DK2785368T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK12854165.3T 2011-12-02 2012-11-30 Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider DK2785368T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161566234P 2011-12-02 2011-12-02
PCT/US2012/067483 WO2013082558A1 (en) 2011-12-02 2012-11-30 Immunogenic composition comprising panton-valentine leukocidin (pvl) derived polypeptides

Publications (1)

Publication Number Publication Date
DK2785368T3 true DK2785368T3 (da) 2019-05-27

Family

ID=48536149

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12854165.3T DK2785368T3 (da) 2011-12-02 2012-11-30 Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider

Country Status (13)

Country Link
US (1) US10023848B2 (da)
EP (1) EP2785368B1 (da)
JP (1) JP6325452B2 (da)
KR (1) KR101999299B1 (da)
AU (1) AU2012345645B2 (da)
CA (1) CA2857666C (da)
DK (1) DK2785368T3 (da)
ES (1) ES2728445T3 (da)
HR (1) HRP20190907T1 (da)
LT (1) LT2785368T (da)
RS (1) RS58919B1 (da)
SI (1) SI2785368T1 (da)
WO (1) WO2013082558A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2785368T3 (da) 2011-12-02 2019-05-27 Integrated Biotherapeutics Inc Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider
DK3441474T3 (da) 2013-06-18 2020-08-17 Univ New York Farmaceutiske sammensætninger indeholdende et muteret leukocidin e
US9815872B2 (en) 2013-06-19 2017-11-14 Integrated Biotherapeutics, Inc. Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
US9017698B2 (en) 2013-09-25 2015-04-28 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9504743B2 (en) 2013-09-25 2016-11-29 Sequoia Sciences, Inc Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9149522B2 (en) 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9149521B2 (en) 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
EP3057989A1 (en) * 2013-10-17 2016-08-24 ARSANIS Biosciences GmbH Cross-reactive staphylococcus aureus antibody sequences
JP6620817B2 (ja) * 2015-08-10 2019-12-18 株式会社微生物化学研究所 黄色ブドウ球菌不活化菌体とロイコシジンを混合したワクチン
CN107224575B (zh) * 2017-03-06 2018-11-09 浙江海隆生物科技有限公司 奶牛金黄色葡萄球菌乳房炎亚单位疫苗的组合物及其制备方法和应用
WO2019023341A1 (en) 2017-07-27 2019-01-31 Integrated Biotherapeutics, Inc. IMMUNOGENIC COMPOSITION COMPRISING A MELTING PEPTIDE DERIVED FROM TOXOIDS OF SUPERANTIGENES

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20100158871A1 (en) 1999-08-30 2010-06-24 David Stephen Terman Sickled erythrocytes with antitumor molecules induce tumoricidal effects
US20050008633A1 (en) 2003-05-19 2005-01-13 Advanced Inhalation Research Inc. Chemical and physical modulators of bioavailability of inhaled compositions
AR055580A1 (es) * 2005-06-13 2007-08-29 Nabi Biopharmaceuticals Uso de leucocidina de panton valentine para el tratamiento y prevencion de infecciones por estafilococos
US7754225B2 (en) 2006-07-20 2010-07-13 Glaxosmithkline Biologicals S.A. Method of protecting against staphylococcal infection
EP2388593A3 (fr) * 2006-10-18 2012-01-18 bioMérieux Procédé de diagnostic in vitro des Staphylococcus aureus producteurs de PVL
DK2785368T3 (da) 2011-12-02 2019-05-27 Integrated Biotherapeutics Inc Immunogen sammensætning, der omfatter panton-valentine-leukocidin (pvl)-afledte polypeptider

Also Published As

Publication number Publication date
RS58919B1 (sr) 2019-08-30
CA2857666C (en) 2020-08-11
US20140308291A1 (en) 2014-10-16
ES2728445T3 (es) 2019-10-24
KR101999299B1 (ko) 2019-07-12
EP2785368A4 (en) 2015-12-30
KR20140117381A (ko) 2014-10-07
LT2785368T (lt) 2019-06-10
EP2785368B1 (en) 2019-03-13
SI2785368T1 (sl) 2019-08-30
HRP20190907T1 (hr) 2019-07-12
JP2015505831A (ja) 2015-02-26
AU2012345645A1 (en) 2014-06-26
NZ626762A (en) 2016-07-29
EP2785368A1 (en) 2014-10-08
JP6325452B2 (ja) 2018-05-16
CA2857666A1 (en) 2013-06-06
US10023848B2 (en) 2018-07-17
AU2012345645B2 (en) 2017-09-07
WO2013082558A1 (en) 2013-06-06

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