HRP20190378T1 - Prolijekovi tetrahidrokanabinola, pripravci koji sadržavaju prolijekove tetrahidrokanabinola i postupci za njihovu uporabu - Google Patents

Prolijekovi tetrahidrokanabinola, pripravci koji sadržavaju prolijekove tetrahidrokanabinola i postupci za njihovu uporabu

Info

Publication number
HRP20190378T1
HRP20190378T1 HRP20190378TT HRP20190378T HRP20190378T1 HR P20190378 T1 HRP20190378 T1 HR P20190378T1 HR P20190378T T HRP20190378T T HR P20190378TT HR P20190378 T HRP20190378 T HR P20190378T HR P20190378 T1 HRP20190378 T1 HR P20190378T1
Authority
HR
Croatia
Prior art keywords
tetrahydrocannabinol
prodrugs
compositions
methods
same
Prior art date
Application number
HRP20190378TT
Other languages
English (en)
Inventor
Audra Lynn Stinchcomb
Miroslaw Jerzy Golinski
Dana Carmel Hammell
Jeffry Lynn Howard
Original Assignee
Zynerba Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zynerba Pharmaceuticals, Inc. filed Critical Zynerba Pharmaceuticals, Inc.
Publication of HRP20190378T1 publication Critical patent/HRP20190378T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
HRP20190378TT 2007-11-30 2019-02-28 Prolijekovi tetrahidrokanabinola, pripravci koji sadržavaju prolijekove tetrahidrokanabinola i postupci za njihovu uporabu HRP20190378T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99155507P 2007-11-30 2007-11-30
US3756808P 2008-03-18 2008-03-18
EP15172043.0A EP2963031B1 (en) 2007-11-30 2008-12-01 Prodrugs of tetrahydrocannabinol, compositions comprising prodrugs of tetrahydrocannabinol and methods of using the same

Publications (1)

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HRP20190378T1 true HRP20190378T1 (hr) 2019-04-19

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HRP20151029TT HRP20151029T1 (hr) 2007-11-30 2015-09-29 Prolijekovi tetrahidrokanabinola, pripravci koji sadržavaju prolijekove tetrahidrokanabinola postupci za njihovu uporabu
HRP20190378TT HRP20190378T1 (hr) 2007-11-30 2019-02-28 Prolijekovi tetrahidrokanabinola, pripravci koji sadržavaju prolijekove tetrahidrokanabinola i postupci za njihovu uporabu

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US (12) US8227627B2 (hr)
EP (2) EP2215071B1 (hr)
JP (3) JP5551604B2 (hr)
CA (3) CA2977722C (hr)
CY (2) CY1116927T1 (hr)
DK (2) DK2215071T3 (hr)
ES (2) ES2716407T3 (hr)
HK (1) HK1219733A1 (hr)
HR (2) HRP20151029T1 (hr)
HU (2) HUE027707T2 (hr)
LT (1) LT2963031T (hr)
MX (1) MX2010005931A (hr)
PL (2) PL2963031T3 (hr)
PT (2) PT2963031T (hr)
SI (2) SI2215071T1 (hr)
WO (1) WO2009073633A1 (hr)

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ES2716407T3 (es) * 2007-11-30 2019-06-12 Zynerba Pharmaceuticals Inc Profármacos de tetrahidrocannabinol, composiciones que comprenden profármacos de tetrahidrocannabinol y métodos para uso de los mismos
US8829043B2 (en) 2008-02-08 2014-09-09 Nektar Therapeutics Oligome-cannabinoid conjugates
WO2010051541A2 (en) * 2008-10-31 2010-05-06 The University Of Mississippi Compositions containing delta-9-thc-amino acid esters and process of preparation
US20110245288A1 (en) 2010-04-02 2011-10-06 Alltranz Inc. Transdermally deliverable opioid prodrugs, abuse-resistant compositions and methods of using opioid prodrugs
US8481560B2 (en) 2010-04-02 2013-07-09 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
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