HRP20170416T1 - Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba - Google Patents

Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba Download PDF

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Publication number
HRP20170416T1
HRP20170416T1 HRP20170416TT HRP20170416T HRP20170416T1 HR P20170416 T1 HRP20170416 T1 HR P20170416T1 HR P20170416T T HRP20170416T T HR P20170416TT HR P20170416 T HRP20170416 T HR P20170416T HR P20170416 T1 HRP20170416 T1 HR P20170416T1
Authority
HR
Croatia
Prior art keywords
platinum
reaction mixture
pyrophosphate
substituted
monomer complex
Prior art date
Application number
HRP20170416TT
Other languages
English (en)
Croatian (hr)
Inventor
Wayne D. Luke
Steffen Jost
Original Assignee
Phosplatin Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phosplatin Therapeutics Llc filed Critical Phosplatin Therapeutics Llc
Publication of HRP20170416T1 publication Critical patent/HRP20170416T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20170416TT 2012-05-24 2013-03-15 Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba HRP20170416T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651200P 2012-05-24 2012-05-24
PCT/US2013/031885 WO2013176764A1 (en) 2012-05-24 2013-03-15 Synthetic and purification methods for phosphaplatin compounds and uses thereof
EP13793812.2A EP2855496B1 (en) 2012-05-24 2013-03-15 Synthetic and purification methods for phosphaplatin compounds and uses thereof

Publications (1)

Publication Number Publication Date
HRP20170416T1 true HRP20170416T1 (hr) 2017-05-19

Family

ID=49624225

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20170416TT HRP20170416T1 (hr) 2012-05-24 2013-03-15 Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba
HRP20191904TT HRP20191904T1 (hr) 2012-05-24 2019-10-21 Postupak pročišćavanja spojeva fosfaplatine

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20191904TT HRP20191904T1 (hr) 2012-05-24 2019-10-21 Postupak pročišćavanja spojeva fosfaplatine

Country Status (18)

Country Link
US (2) US8846964B2 (cg-RX-API-DMAC7.html)
EP (2) EP2855496B1 (cg-RX-API-DMAC7.html)
JP (1) JP5833795B2 (cg-RX-API-DMAC7.html)
CN (2) CN106967124B (cg-RX-API-DMAC7.html)
CY (2) CY1118746T1 (cg-RX-API-DMAC7.html)
DK (2) DK3202769T3 (cg-RX-API-DMAC7.html)
ES (2) ES2619412T3 (cg-RX-API-DMAC7.html)
HR (2) HRP20170416T1 (cg-RX-API-DMAC7.html)
HU (2) HUE032197T2 (cg-RX-API-DMAC7.html)
IN (1) IN2014KN02722A (cg-RX-API-DMAC7.html)
LT (2) LT2855496T (cg-RX-API-DMAC7.html)
PL (2) PL3202769T3 (cg-RX-API-DMAC7.html)
PT (2) PT3202769T (cg-RX-API-DMAC7.html)
RS (2) RS59725B1 (cg-RX-API-DMAC7.html)
SI (2) SI2855496T1 (cg-RX-API-DMAC7.html)
SM (2) SMT201700168T1 (cg-RX-API-DMAC7.html)
TW (2) TWI653237B (cg-RX-API-DMAC7.html)
WO (1) WO2013176764A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3202769T (pt) * 2012-05-24 2019-10-31 Phosplatin Therapeutics Llc Processos de síntese e de purificação para compostos de fosfaplatina e aplicações dos mesmos
KR102419247B1 (ko) * 2016-04-06 2022-07-11 포스플라틴 테라퓨틱스 인코포레이티드 포스파플라틴 액제 제형
CN110381952B (zh) 2017-01-06 2023-10-20 弗斯普拉廷治疗有限公司 作为治疗剂用于治疗骨癌或血癌的磷铂化合物
JP7381083B2 (ja) * 2017-09-08 2023-11-15 フォスプラティン テラピューティクス インコーポレイテッド 免疫調節剤としてのホスファプラチン化合物およびその治療的使用
CN113861036B (zh) * 2021-11-08 2024-04-02 合肥工业大学 一种乙二胺高氯酸铜配合物的制备及用途
US11673904B1 (en) * 2021-12-09 2023-06-13 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Low pressure process for synthesis of Pt(PF3)4 involving a soluble intermediate and storage of obtained Pt(PF3)4
CN119822568B (zh) * 2025-02-19 2025-08-19 扬州宏鑫环保科技有限公司 一种高效纯化水制备装置及制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
WO2005000858A2 (en) 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
KR20080096682A (ko) * 2006-01-30 2008-10-31 플라트코 테크놀로지스 (프로프라이어터리) 리미티드 백금(ⅱ) 착물의 제조법
NZ582049A (en) * 2007-05-18 2012-12-21 Tti Ellebeau Inc Transdermal delivery devices assuring an improved release of an active principle through a biological interface
PL2173337T3 (pl) 2007-08-06 2014-11-28 Univ Ohio Fosfaplatyny i ich zastosowanie w leczeniu raków opornych na cisplatynę i karboplatynę
JP5860872B2 (ja) * 2010-06-04 2016-02-16 オハイオ ユニバーシティー ホスファプラチン、及び癌治療のためのそれらの使用
MX357865B (es) * 2011-10-05 2018-07-25 N Bose Rathindra Procedimientos eficientes para preparación a gran escala de agentes antitumorales de fosfaplatinos.
PT3202769T (pt) * 2012-05-24 2019-10-31 Phosplatin Therapeutics Llc Processos de síntese e de purificação para compostos de fosfaplatina e aplicações dos mesmos

Also Published As

Publication number Publication date
HUE046327T2 (hu) 2020-03-30
HUE032197T2 (en) 2017-09-28
CY1118746T1 (el) 2018-03-07
PL2855496T3 (pl) 2017-09-29
US8859796B1 (en) 2014-10-14
DK3202769T3 (da) 2019-10-28
LT2855496T (lt) 2017-04-10
TWI599361B (zh) 2017-09-21
CN104540839A (zh) 2015-04-22
CY1122316T1 (el) 2021-01-27
SMT201700168T1 (it) 2017-05-08
EP2855496A1 (en) 2015-04-08
DK2855496T3 (en) 2017-03-27
PL3202769T3 (pl) 2020-03-31
EP3202769A1 (en) 2017-08-09
ES2751668T3 (es) 2020-04-01
US8846964B2 (en) 2014-09-30
US20140024848A1 (en) 2014-01-23
CN106967124A (zh) 2017-07-21
SI3202769T1 (sl) 2020-02-28
US20140288321A1 (en) 2014-09-25
PT3202769T (pt) 2019-10-31
EP2855496A4 (en) 2015-04-08
TWI653237B (zh) 2019-03-11
RS59725B1 (sr) 2020-01-31
LT3202769T (lt) 2019-12-10
EP2855496B1 (en) 2016-12-14
HRP20191904T1 (hr) 2020-01-24
RS55806B1 (sr) 2017-08-31
JP2015523335A (ja) 2015-08-13
ES2619412T3 (es) 2017-06-26
SI2855496T1 (sl) 2017-04-26
CN104540839B (zh) 2017-02-22
EP3202769B1 (en) 2019-10-02
PT2855496T (pt) 2017-03-23
TW201347765A (zh) 2013-12-01
TW201741326A (zh) 2017-12-01
CN106967124B (zh) 2020-03-06
WO2013176764A1 (en) 2013-11-28
SMT201900617T1 (it) 2020-01-14
IN2014KN02722A (cg-RX-API-DMAC7.html) 2015-05-08
HK1203202A1 (en) 2015-10-23
JP5833795B2 (ja) 2015-12-16

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