HRP20150889T1 - Postupci za lijeäśenje adhezivnog kapsulitisa - Google Patents
Postupci za lijeäśenje adhezivnog kapsulitisa Download PDFInfo
- Publication number
- HRP20150889T1 HRP20150889T1 HRP20150889TT HRP20150889T HRP20150889T1 HR P20150889 T1 HRP20150889 T1 HR P20150889T1 HR P20150889T T HRP20150889T T HR P20150889TT HR P20150889 T HRP20150889 T HR P20150889T HR P20150889 T1 HRP20150889 T1 HR P20150889T1
- Authority
- HR
- Croatia
- Prior art keywords
- collagenase
- use according
- degrees
- less
- external rotation
- Prior art date
Links
- 206010034464 Periarthritis Diseases 0.000 title claims 3
- 102000029816 Collagenase Human genes 0.000 claims 18
- 108060005980 Collagenase Proteins 0.000 claims 18
- 229960002424 collagenase Drugs 0.000 claims 18
- 238000002347 injection Methods 0.000 claims 4
- 239000007924 injection Substances 0.000 claims 4
- 241000193159 Hathewaya histolytica Species 0.000 claims 2
- YRQNKMKHABXEJZ-UVQQGXFZSA-N chembl176323 Chemical compound C1C[C@]2(C)[C@@]3(C)CC(N=C4C[C@]5(C)CCC6[C@]7(C)CC[C@@H]([C@]7(CC[C@]6(C)[C@@]5(C)CC4=N4)C)CCCCCCCC)=C4C[C@]3(C)CCC2[C@]2(C)CC[C@H](CCCCCCCC)[C@]21C YRQNKMKHABXEJZ-UVQQGXFZSA-N 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24007—Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
Claims (9)
1. Uporaba kolagenaze za proizvodnju lijeka za liječenje adhezivnog kapsulitisa kod subjekta koji je čovjek kojem treba takvo liječenje, naznačena time da se navedeni pripravak dostavlja u kolagene adhezije u ramenu pri čemu se kolagenaza dobiva od iz soja bakterija Clostridium histolyticum, te pri čemu se u razmaku od 4 do 6 tjedana daju najmanje dvije injekcije od najmanje 700 SRC jedinica kolagenaze.
2. Uporaba prema zahtjevu 1, naznačena time da svaka injekcija kolagenaze ima volumen od 0.5 ml ili manje.
3. Uporaba prema zahtjevu 1 ili zahtjevu 2, naznačena time da kolagenaza sadrži kolagenazu I i kolagenazu II.
4. Uporaba prema bilo kojem prethodnom zahtjevu, čemu je pacijent naznačen time da ima nagib prema naprijed od samo 90 stupnjeva i aktivnu vanjsku rotaciju od manje od 50 stupnjeva.
5. Uporaba prema bilo kojem od zahtjeva 1 do 3, naznačena time da nakon jednog mjeseca primanja najmanje jednog davanja kolagenaze, pacijent postiže aktivnu vanjsku rotaciju veću od 15º, u usporedbi s početnim stanjem.
6. Kolagenaza za uporabu za liječenje adhezivnog kapsulitisa kod subjekta koji je čovjek, naznačena time da se navedena kolagenaza dostavlja u kolagene adhezije u ramenu, pri čemu se kolagenaza dobiva od iz soja bakterija Clostridium histolyticum, te pri čemu se u razmaku od 4 do 6 tjedana daju najmanje dvije injekcije od najmanje 700 SRC jedinica kolagenaze.
7. Kolagenaza za uporabu prema zahtjevu 6, naznačena time da:
a) svaka injekcija kolagenaze ima volumen od 0.5 ml ili manje; i/ili
b) kolagenaza sadrži kolagenazu I i kolagenazu II.
8. Kolagenaza za uporabu prema zahtjevu ili zahtjevu 7, pri čemu je pacijent naznačen time da ima aktivan nagib prema naprijed od samo 90 stupnjeva i aktivnu vanjsku rotaciju od manje od 50 stupnjeva.
9. Kolagenaza za uporabu prema zahtjevu 6 ili zahtjevu 7, naznačena time da nakon jednog mjeseca primanja najmanje jednog davanja kolagenaze, pacijent postiže aktivnu vanjsku rotaciju veću od 15º, u usporedbi s početnim stanjem.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64577205P | 2005-01-21 | 2005-01-21 | |
| US67744005P | 2005-05-03 | 2005-05-03 | |
| US71947005P | 2005-09-22 | 2005-09-22 | |
| PCT/US2006/001980 WO2006078870A2 (en) | 2005-01-21 | 2006-01-19 | Methods for treating adhesive capsulitis |
| EP06718969.6A EP1846022B1 (en) | 2005-01-21 | 2006-01-19 | Methods for treating adhesive capsulitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20150889T1 true HRP20150889T1 (hr) | 2015-11-20 |
Family
ID=36692898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20150889TT HRP20150889T1 (hr) | 2005-01-21 | 2015-08-20 | Postupci za lijeäśenje adhezivnog kapsulitisa |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US20060204488A1 (hr) |
| EP (2) | EP1846022B1 (hr) |
| JP (1) | JP4967081B2 (hr) |
| KR (2) | KR20090130158A (hr) |
| CN (1) | CN101107006B (hr) |
| AU (1) | AU2006206393B2 (hr) |
| BR (1) | BRPI0607280A2 (hr) |
| CA (1) | CA2593038C (hr) |
| CY (1) | CY1120193T1 (hr) |
| DK (1) | DK1846022T3 (hr) |
| ES (1) | ES2548516T3 (hr) |
| HK (3) | HK1109592A1 (hr) |
| HR (1) | HRP20150889T1 (hr) |
| HU (1) | HUE027236T2 (hr) |
| ME (1) | ME02344B (hr) |
| MX (1) | MX2007008764A (hr) |
| NZ (1) | NZ556160A (hr) |
| PL (1) | PL1846022T3 (hr) |
| PT (1) | PT1846022E (hr) |
| RS (1) | RS54265B1 (hr) |
| SI (1) | SI1846022T1 (hr) |
| WO (1) | WO2006078870A2 (hr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6958150B2 (en) | 1994-12-15 | 2005-10-25 | Advance Biofactures Of Curacao, N.V. | Reduction of adipose tissue |
| US20070224184A1 (en) * | 2006-02-22 | 2007-09-27 | The Research Foundation Of The State University Of New York | Method for treating cellulite |
| US7811560B2 (en) * | 2006-01-30 | 2010-10-12 | Auxilium Us Holdings, Llc | Compositions and methods for treating collagen-mediated diseases |
| US8323642B2 (en) | 2006-12-13 | 2012-12-04 | Depuy Mitek, Inc. | Tissue fusion method using collagenase for repair of soft tissue |
| US10071143B1 (en) | 2007-05-03 | 2018-09-11 | The Research Foundation For The State University Of New York | Methods for non-surgical treatment of carpal tunnel syndrome |
| DK2274422T3 (en) * | 2008-04-17 | 2017-07-03 | Anaeropharma Science Inc | expression |
| DK2632446T3 (en) * | 2010-10-30 | 2019-04-01 | Univ Oxford Innovation Ltd | TREATMENT OF DUPUYTRY CONTRACT |
| WO2013034416A1 (en) | 2011-09-09 | 2013-03-14 | Unilever N.V. | Antimicrobial method and composition |
| WO2013106510A2 (en) | 2012-01-12 | 2013-07-18 | Auxilium Pharmaceuticals, Inc. | Clostridium histolyticum enzymes and methods for the use thereof |
| WO2014066622A2 (en) | 2012-10-24 | 2014-05-01 | The Research Foundation For The State University Of New York | Use of collagenase to treat glaucoma |
| CN115969318A (zh) | 2017-03-01 | 2023-04-18 | 恩多风投有限公司 | 用于评估和治疗橘皮组织的装置和方法 |
| KR102642381B1 (ko) | 2017-03-28 | 2024-02-28 | 엔도 벤쳐즈 리미티드 | 개선된 콜라게나제 생성 방법 |
| RU2745328C1 (ru) * | 2020-05-24 | 2021-03-23 | Федеральное государственное бюджетное учреждение «Федеральный центр травматологии, ортопедии и эндопротезирования» Министерства здравоохранения и социального развития РФ (г. Чебоксары) | Способ лечения болевого синдрома при адгезивном капсулите |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4524065A (en) * | 1983-08-04 | 1985-06-18 | Bio-Specifics N.V. | Method for the prevention and treatment of scars with enzymes |
| DE4200080A1 (de) * | 1992-01-03 | 1993-09-30 | Reinmueller Johannes | Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung |
| US5589171A (en) * | 1994-08-22 | 1996-12-31 | Advance Biofactures Of Curacao | Treatment of Dupuytren's disease with collagenase |
| US5989888A (en) * | 1996-01-24 | 1999-11-23 | Roche Diagnostics Corporation | Purified mixture of collagenase I, collagenase II and two other proteases |
| US5830741A (en) | 1996-12-06 | 1998-11-03 | Boehringer Mannheim Corporation | Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease |
| US6086872A (en) * | 1997-03-27 | 2000-07-11 | Advance Biofactures Of Curacao, Nv | Amelioration of dupuytren's disease |
| US6060474A (en) | 1998-11-05 | 2000-05-09 | New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method for preventing scar tissue formation |
| US6022539A (en) * | 1999-06-03 | 2000-02-08 | Advance Biofactures Of Curacao | Amelioration of peyronie's disease |
| EP1433845A1 (en) | 2002-12-23 | 2004-06-30 | Georg-August-Universität | Clostridium tetani collagenase and uses thereof |
| US7854929B2 (en) * | 2005-01-21 | 2010-12-21 | The Research Foundation Of State University Of New York | Method for treating lateral epicondylitis using collagenase |
| US20070224184A1 (en) * | 2006-02-22 | 2007-09-27 | The Research Foundation Of The State University Of New York | Method for treating cellulite |
-
2006
- 2006-01-19 US US11/335,157 patent/US20060204488A1/en not_active Abandoned
- 2006-01-19 AU AU2006206393A patent/AU2006206393B2/en not_active Ceased
- 2006-01-19 HU HUE06718969A patent/HUE027236T2/en unknown
- 2006-01-19 KR KR1020097025614A patent/KR20090130158A/ko not_active Application Discontinuation
- 2006-01-19 MX MX2007008764A patent/MX2007008764A/es active IP Right Grant
- 2006-01-19 SI SI200631968T patent/SI1846022T1/sl unknown
- 2006-01-19 DK DK06718969.6T patent/DK1846022T3/en active
- 2006-01-19 ME MEP-2016-25A patent/ME02344B/me unknown
- 2006-01-19 PL PL06718969T patent/PL1846022T3/pl unknown
- 2006-01-19 CA CA2593038A patent/CA2593038C/en active Active
- 2006-01-19 PT PT67189696T patent/PT1846022E/pt unknown
- 2006-01-19 JP JP2007552280A patent/JP4967081B2/ja not_active Expired - Fee Related
- 2006-01-19 ES ES06718969.6T patent/ES2548516T3/es active Active
- 2006-01-19 EP EP06718969.6A patent/EP1846022B1/en active Active
- 2006-01-19 BR BRPI0607280-1A patent/BRPI0607280A2/pt not_active Application Discontinuation
- 2006-01-19 NZ NZ556160A patent/NZ556160A/en not_active IP Right Cessation
- 2006-01-19 KR KR1020077018990A patent/KR100989267B1/ko active IP Right Grant
- 2006-01-19 WO PCT/US2006/001980 patent/WO2006078870A2/en active Application Filing
- 2006-01-19 RS RS20150550A patent/RS54265B1/en unknown
- 2006-01-19 EP EP15001499.1A patent/EP2977058A1/en not_active Ceased
- 2006-01-19 CN CN2006800029696A patent/CN101107006B/zh not_active Expired - Fee Related
-
2008
- 2008-04-19 HK HK08104403.5A patent/HK1109592A1/xx not_active IP Right Cessation
- 2008-04-21 HK HK08104422.2A patent/HK1115295A1/xx not_active IP Right Cessation
- 2008-11-06 US US12/266,090 patent/US8323643B2/en active Active
-
2012
- 2012-11-29 US US13/688,387 patent/US20130330320A1/en not_active Abandoned
-
2014
- 2014-12-16 US US14/572,104 patent/US20150174216A1/en not_active Abandoned
-
2015
- 2015-08-20 HR HRP20150889TT patent/HRP20150889T1/hr unknown
- 2015-08-20 CY CY20151100725T patent/CY1120193T1/el unknown
-
2016
- 2016-06-03 US US15/173,497 patent/US20160354450A1/en not_active Abandoned
- 2016-07-27 HK HK16109019.0A patent/HK1221143A1/zh unknown
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