HRP20130991T1 - Dijagnostiäśki sastav nadmoä†nog sigurnosnog profila koji obuhvaä†a katione plazme - Google Patents
Dijagnostiäśki sastav nadmoä†nog sigurnosnog profila koji obuhvaä†a katione plazme Download PDFInfo
- Publication number
- HRP20130991T1 HRP20130991T1 HRP20130991AT HRP20130991T HRP20130991T1 HR P20130991 T1 HRP20130991 T1 HR P20130991T1 HR P20130991A T HRP20130991A T HR P20130991AT HR P20130991 T HRP20130991 T HR P20130991T HR P20130991 T1 HRP20130991 T1 HR P20130991T1
- Authority
- HR
- Croatia
- Prior art keywords
- substance
- diagnostic composition
- composition according
- sodium
- calcium
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 16
- 150000001768 cations Chemical class 0.000 title 1
- 239000000126 substance Substances 0.000 claims 18
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 7
- 239000011575 calcium Substances 0.000 claims 7
- 229910052791 calcium Inorganic materials 0.000 claims 7
- 239000011734 sodium Substances 0.000 claims 7
- 229910052708 sodium Inorganic materials 0.000 claims 7
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 6
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 6
- 229910001424 calcium ion Inorganic materials 0.000 claims 6
- 229910001415 sodium ion Inorganic materials 0.000 claims 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical group [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 239000007983 Tris buffer Substances 0.000 claims 1
- 239000001110 calcium chloride Substances 0.000 claims 1
- 229910001628 calcium chloride Inorganic materials 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0452—Solutions, e.g. for injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Claims (15)
1. Dijagnostički sastav obuhvaća Tvar 1
[image]
Tvar 1
farmaceutski prihvatljivi nosač;
i u njemu otopljenu natrijevu tvar i kalcijevu tvar koji omogućava koncentraciju natrijevog iona od 40-50 mM i koncentraciju kalcijevog iona od 0.1-0.7 mM.
2. Dijagnostički sastav prema patentnom zahtjevu 1 obuhvaća natrijevu tvar koja omogućuje koncentraciju natrijevog iona od 42-47 mM.
3. Dijagnostički sastav prema patentnom zahtjevu 1 obuhvaća natrijevu tvar koja omogućuje koncentraciju natrijevog iona od 44-46 mM.
4. Dijagnostički sastav prema patentnom zahtjevu 1 obuhvaća natrijevu tvar koja omogućuje koncentraciju natrijevog iona od 45 mM.
5. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 4 obuhvaća kalcijevu tvar koja omogućuje koncentraciju kalcijevog iona od 0.3-0.6 mM.
6. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 4 obuhvaća kalcijevu tvar koja omogućuje koncentraciju kalcijevog iona od 0.4-0.5 mM.
7. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 4 obuhvaća kalcijevu tvar koja omogućuje koncentraciju kalcijevog iona od 0.5 mM.
8. Dijagnostički sastav prema patentnom zahtjevu 1 pri čemu je omjer između koncentracije natrijevog iona i koncentracije kalcijevog iona između 63 i 117.
9. Dijagnostički sastav obuhvaća tvar 1
[image]
Tvar 1
farmaceutski prihvatljivi nosač;
i u njemu otopljenu natrijevu tvar i kalcijevu tvar pri čemu je omjer između koncentracije natrijevog iona i koncentracije kalcijevog iona između 40 i 45.
10. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 9 pri čemu su natrijeva tvar i kalcijeva tvar soli koje obuhvaćaju suprotno nabijene ione odabrane iz grupe klorida, sulfata, fosfata i hidrogen karbonata.
11. Dijagnostički sastav prema patentnom zahtjevu 10 pri čemu je natrijeva tvar natrijev klorid, a kalcijeva tvar je kalcijev klorid.
12. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 11 nadalje obuhvaća EDTA i/ili TRIS.
13. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 1 do 12 za uporabu kao kontrastni medij za X-zračenje u dijagnostici X-zračenjem ili slikovnu dijagnostiku X-zračenjem.
14. Dijagnostički sastav prema patentnom zahtjevu 13 pri čemu uporaba uključuje pregled tijela pomoću dijagnostičke naprave i sakupljanje podataka pregleda.
15. Dijagnostički sastav prema bilo kojem od patentnih zahtjeva 13 i 14 pri čemu je uporaba metoda koronarne atreriografije.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09174413 | 2009-10-29 | ||
| PCT/EP2010/066351 WO2011051387A1 (en) | 2009-10-29 | 2010-10-28 | Diagnostic composition comprising plasma cations having superior safety profile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20130991T1 true HRP20130991T1 (hr) | 2013-12-20 |
Family
ID=43503035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20130991AT HRP20130991T1 (hr) | 2009-10-29 | 2013-10-21 | Dijagnostiäśki sastav nadmoä†nog sigurnosnog profila koji obuhvaä†a katione plazme |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8815210B2 (hr) |
| EP (1) | EP2493511B1 (hr) |
| JP (1) | JP5335147B2 (hr) |
| KR (1) | KR101545045B1 (hr) |
| CN (1) | CN102596257B (hr) |
| AU (1) | AU2010311478B2 (hr) |
| BR (1) | BR112012009859B1 (hr) |
| CA (1) | CA2773685C (hr) |
| CO (1) | CO6531477A2 (hr) |
| DK (1) | DK2493511T3 (hr) |
| ES (1) | ES2435299T3 (hr) |
| HR (1) | HRP20130991T1 (hr) |
| IL (1) | IL218456A (hr) |
| IN (1) | IN2012DN02126A (hr) |
| MX (1) | MX2012005021A (hr) |
| NZ (1) | NZ598540A (hr) |
| PL (1) | PL2493511T3 (hr) |
| PT (1) | PT2493511E (hr) |
| RU (1) | RU2544113C2 (hr) |
| WO (1) | WO2011051387A1 (hr) |
| ZA (1) | ZA201203505B (hr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO333914B1 (no) * | 2011-12-21 | 2013-10-21 | Ge Healthcare As | Stabilisering av diagnostisk røntgensammensetning |
| CA2862495A1 (en) * | 2012-01-11 | 2013-07-18 | Ge Healthcare As | X-ray imaging contrast media with low iodine concentration and x-ray imaging process |
| CN105579069A (zh) * | 2013-03-27 | 2016-05-11 | 通用电气医疗集团股份有限公司 | 用于制备诊断组合物的方法和试剂 |
| US10575744B2 (en) | 2017-02-24 | 2020-03-03 | Medtronic Cryocath Lp | Pericardial balloon mapping |
| CN109876157B (zh) * | 2019-02-27 | 2020-12-15 | 浙江大学 | 离子特异性滤膜/介孔硅的复合材料、纳米传感器及其产品和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0108638B1 (en) * | 1982-11-08 | 1986-07-16 | NYEGAARD & CO. A/S | X-ray contrast agents |
| GB8906130D0 (en) * | 1989-03-17 | 1989-05-04 | Nycomed As | Compositions |
| GB9020091D0 (en) | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| DE4344464A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Kaskadenpolymere mit Iodaromaten |
| GB9419203D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
| US8066970B2 (en) * | 2006-05-11 | 2011-11-29 | Ge Healthcare As | Contrast agents |
| BRPI0814811A2 (pt) | 2007-07-12 | 2015-02-03 | Ge Healthcare As | Composto, agente, método, e composição de diagnóstico, uso de um composto, e, método de formação de imagem |
-
2010
- 2010-10-28 JP JP2012535827A patent/JP5335147B2/ja not_active Expired - Fee Related
- 2010-10-28 ES ES10771120T patent/ES2435299T3/es active Active
- 2010-10-28 IN IN2126DEN2012 patent/IN2012DN02126A/en unknown
- 2010-10-28 PL PL10771120T patent/PL2493511T3/pl unknown
- 2010-10-28 EP EP10771120.2A patent/EP2493511B1/en not_active Not-in-force
- 2010-10-28 DK DK10771120.2T patent/DK2493511T3/da active
- 2010-10-28 PT PT107711202T patent/PT2493511E/pt unknown
- 2010-10-28 US US13/497,641 patent/US8815210B2/en not_active Expired - Fee Related
- 2010-10-28 MX MX2012005021A patent/MX2012005021A/es active IP Right Grant
- 2010-10-28 CN CN2010800498286A patent/CN102596257B/zh not_active Expired - Fee Related
- 2010-10-28 WO PCT/EP2010/066351 patent/WO2011051387A1/en active Application Filing
- 2010-10-28 AU AU2010311478A patent/AU2010311478B2/en not_active Ceased
- 2010-10-28 BR BR112012009859A patent/BR112012009859B1/pt not_active IP Right Cessation
- 2010-10-28 NZ NZ598540A patent/NZ598540A/en not_active IP Right Cessation
- 2010-10-28 KR KR1020127010930A patent/KR101545045B1/ko active IP Right Grant
- 2010-10-28 CA CA2773685A patent/CA2773685C/en not_active Expired - Fee Related
- 2010-10-28 RU RU2012116882/15A patent/RU2544113C2/ru not_active IP Right Cessation
-
2012
- 2012-03-04 IL IL218456A patent/IL218456A/en not_active IP Right Cessation
- 2012-04-25 CO CO12068011A patent/CO6531477A2/es unknown
- 2012-05-14 ZA ZA2012/03505A patent/ZA201203505B/en unknown
-
2013
- 2013-10-21 HR HRP20130991AT patent/HRP20130991T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2493511T3 (pl) | 2014-05-30 |
| WO2011051387A1 (en) | 2011-05-05 |
| EP2493511B1 (en) | 2013-10-16 |
| MX2012005021A (es) | 2012-06-19 |
| RU2012116882A (ru) | 2013-12-10 |
| IN2012DN02126A (hr) | 2015-08-21 |
| AU2010311478B2 (en) | 2015-09-24 |
| KR20120091149A (ko) | 2012-08-17 |
| EP2493511A1 (en) | 2012-09-05 |
| US20120328522A1 (en) | 2012-12-27 |
| AU2010311478A1 (en) | 2012-03-29 |
| CA2773685A1 (en) | 2011-05-05 |
| BR112012009859B1 (pt) | 2019-10-22 |
| DK2493511T3 (da) | 2013-11-25 |
| KR101545045B1 (ko) | 2015-08-17 |
| CO6531477A2 (es) | 2012-09-28 |
| IL218456A0 (en) | 2012-04-30 |
| PT2493511E (pt) | 2013-11-18 |
| ZA201203505B (en) | 2013-01-31 |
| ES2435299T3 (es) | 2013-12-18 |
| CN102596257A (zh) | 2012-07-18 |
| CN102596257B (zh) | 2013-08-21 |
| IL218456A (en) | 2015-08-31 |
| US8815210B2 (en) | 2014-08-26 |
| JP5335147B2 (ja) | 2013-11-06 |
| BR112012009859A2 (pt) | 2016-08-30 |
| NZ598540A (en) | 2014-03-28 |
| RU2544113C2 (ru) | 2015-03-10 |
| CA2773685C (en) | 2016-05-31 |
| JP2013509378A (ja) | 2013-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20130991T1 (hr) | Dijagnostiäśki sastav nadmoä†nog sigurnosnog profila koji obuhvaä†a katione plazme | |
| CN103420364B (zh) | 一种石墨烯/羟基磷灰石复合材料的制备方法 | |
| MX2009005413A (es) | Formas cristalinas del acido zoledronico. | |
| MX2012006191A (es) | Cartucho para purificacion de agua que usa sorbentes de intercambio ionico de zirconio. | |
| BRPI0906261A2 (pt) | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" | |
| WO2011109835A3 (en) | Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution | |
| IL202487A (en) | Annals of 5,5 '- (hydroxyalkyl-diethyl) bis (formylazandyl) bis (2,4,6-triiodophenyl preserved), a diagnostic factor containing them and methods of diagnosis and imaging containing these factors | |
| MX367382B (es) | Composiciones, metodos y sistemas para la sintesis y el uso de agentes trazadores. | |
| PA8747701A1 (es) | Métodos de marcación con flúor radioactivo | |
| BRPI1010028A2 (pt) | métodos de tratamento de encefalopatia hepática | |
| BR112012016767A2 (pt) | Método para diagnosticar se um paciente sofre de uma condição hepática ou do fígado, método para detectar o desenvolvimento de uma patologia do fígado, método para deter5 minar o risco de um paciente para uma condição do fígado e sistema para diagnosticar o estado de saúde hepática | |
| AT503278A3 (de) | Verfahren zur röntgenbildgebung und system zur röntgenbildgebung | |
| BR112012021579A2 (pt) | traçador de tomografia por emissão de pósitron, composto precursor, método para preparar o composto precursor, cassete, composição radiofarmacêutica, método de formação de imagem por tomografia por emissão de pósitron, e, método para diagnose de uma condição. | |
| JP2013509378A5 (hr) | ||
| MX2009005855A (es) | Formulaciones inhalables de bisfosfonato enlazado con polimero y metodos de uso de las mismas. | |
| EA201290245A1 (ru) | Радиоактивно меченные pde10 лиганды | |
| CN104556429A (zh) | 一种水处理药剂组合物及其应用 | |
| TN2009000233A1 (en) | Radiolabelling via fluorination of aziridines | |
| PA8786001A1 (es) | Procedimiento para la preparacion de compuestos de bencimidazol tienilamina y de sus derivados utiles como agentes anhibidores del agente de intercambio sodio/protón del tipo 3" | |
| ATE502571T1 (de) | Anreizverfahren für den spirometrie-test mit universalkontrollsystem unabhängig von einem gewählten stimulationsbild | |
| CN104761066A (zh) | 一种水处理药剂组合物及其应用 | |
| EP2799546A4 (en) | RADIUS EXPOSURE DIAGNOSIS MARKER IGFBP-5, COMPOSITION FOR RADIOGRAPHIC EXPOSURE DIAGNOSIS BY MEASUREMENT OF EXPRESSIVE LEVEL OF MARKER, RADIOGRAPHIC EXPOSURE DIAGNOSIS KIT WITH COMPOSITION AND METHOD FOR DIAGNOSIS OF RADIATION EXPOSURE USING MARKER | |
| FR2934768B1 (fr) | Procede de visualisation de surfaces du corps humain | |
| CR8073A (es) | Iodopyrazolyl carboxanilidas | |
| Gompelmann et al. | Impact Of Heterogeneity Index On Clinical Outcome Following Endobronchial Valve Treatment In Patients With Low Collateral Ventilation-A Subgroup Analysis |