IN2012DN02126A - - Google Patents

Download PDF

Info

Publication number
IN2012DN02126A
IN2012DN02126A IN2126DEN2012A IN2012DN02126A IN 2012DN02126 A IN2012DN02126 A IN 2012DN02126A IN 2126DEN2012 A IN2126DEN2012 A IN 2126DEN2012A IN 2012DN02126 A IN2012DN02126 A IN 2012DN02126A
Authority
IN
India
Prior art keywords
compound
diagnostic
composition
pharmaceutically acceptable
acceptable carrier
Prior art date
Application number
Inventor
Wistrand Lars-Goran
Thaning Mikkel
Newton Ben
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of IN2012DN02126A publication Critical patent/IN2012DN02126A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a new diagnostic X-ray composition which exhibits a superior cardiac safety profile. The composition comprises a non-ionic iodinated dimer in a pharmaceutically acceptable carrier. More particularly, the invention provides a diagnostic composition comprising a Compound I, Compound I a pharmaceutically acceptable carrier, and dissolved therein a sodium compound and a calcium compound providing a sodium ion concentration of 40-50 mM and a calcium ion concentration of 0.1-0.7 mM. The invention also relates to methods of imaging using such diagnostic compositions.
IN2126DEN2012 2009-10-29 2010-10-28 IN2012DN02126A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09174413 2009-10-29
PCT/EP2010/066351 WO2011051387A1 (en) 2009-10-29 2010-10-28 Diagnostic composition comprising plasma cations having superior safety profile

Publications (1)

Publication Number Publication Date
IN2012DN02126A true IN2012DN02126A (en) 2015-08-21

Family

ID=43503035

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2126DEN2012 IN2012DN02126A (en) 2009-10-29 2010-10-28

Country Status (21)

Country Link
US (1) US8815210B2 (en)
EP (1) EP2493511B1 (en)
JP (1) JP5335147B2 (en)
KR (1) KR101545045B1 (en)
CN (1) CN102596257B (en)
AU (1) AU2010311478B2 (en)
BR (1) BR112012009859B1 (en)
CA (1) CA2773685C (en)
CO (1) CO6531477A2 (en)
DK (1) DK2493511T3 (en)
ES (1) ES2435299T3 (en)
HR (1) HRP20130991T1 (en)
IL (1) IL218456A (en)
IN (1) IN2012DN02126A (en)
MX (1) MX2012005021A (en)
NZ (1) NZ598540A (en)
PL (1) PL2493511T3 (en)
PT (1) PT2493511E (en)
RU (1) RU2544113C2 (en)
WO (1) WO2011051387A1 (en)
ZA (1) ZA201203505B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO333914B1 (en) * 2011-12-21 2013-10-21 Ge Healthcare As Stabilization of diagnostic X-ray composition
WO2013104690A1 (en) * 2012-01-11 2013-07-18 Ge Healthcare As X-ray imaging contrast media with low iodine concentration and x-ray imaging process
MX2015013658A (en) * 2013-03-27 2016-02-18 Ge Healthcare As Method and reagent for preparing a diagnostic composition.
US10575744B2 (en) 2017-02-24 2020-03-03 Medtronic Cryocath Lp Pericardial balloon mapping
CN109876157B (en) * 2019-02-27 2020-12-15 浙江大学 Composite material of ion-specific filter membrane/mesoporous silicon, nano sensor, product of nano sensor and application of nano sensor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO161368C (en) * 1982-11-08 1989-08-09 Nyegaard & Co As ROENTGEN CONTRACTORS AND RADIOLOGICAL PREPARATIONS THEREOF.
GB8906130D0 (en) 1989-03-17 1989-05-04 Nycomed As Compositions
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
DE4344464A1 (en) * 1993-12-22 1995-06-29 Schering Ag Cascade polymers with iodine aromatics
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US8066970B2 (en) * 2006-05-11 2011-11-29 Ge Healthcare As Contrast agents
US8920780B2 (en) * 2007-07-12 2014-12-30 Ge Healthcare As Contrast agents

Also Published As

Publication number Publication date
KR20120091149A (en) 2012-08-17
RU2012116882A (en) 2013-12-10
US20120328522A1 (en) 2012-12-27
AU2010311478A1 (en) 2012-03-29
DK2493511T3 (en) 2013-11-25
HRP20130991T1 (en) 2013-12-20
CA2773685C (en) 2016-05-31
BR112012009859B1 (en) 2019-10-22
ES2435299T3 (en) 2013-12-18
CA2773685A1 (en) 2011-05-05
BR112012009859A2 (en) 2016-08-30
JP2013509378A (en) 2013-03-14
MX2012005021A (en) 2012-06-19
CO6531477A2 (en) 2012-09-28
PT2493511E (en) 2013-11-18
EP2493511A1 (en) 2012-09-05
IL218456A (en) 2015-08-31
WO2011051387A1 (en) 2011-05-05
PL2493511T3 (en) 2014-05-30
IL218456A0 (en) 2012-04-30
RU2544113C2 (en) 2015-03-10
KR101545045B1 (en) 2015-08-17
CN102596257B (en) 2013-08-21
ZA201203505B (en) 2013-01-31
CN102596257A (en) 2012-07-18
JP5335147B2 (en) 2013-11-06
US8815210B2 (en) 2014-08-26
NZ598540A (en) 2014-03-28
AU2010311478B2 (en) 2015-09-24
EP2493511B1 (en) 2013-10-16

Similar Documents

Publication Publication Date Title
UA110943C2 (en) N-acyl sulfonamideapoptosis promoters
MX2011013648A (en) New compounds, pharmaceutical composition and methods relating thereto.
IN2012DN02126A (en)
MX2011011513A (en) Methods for improving taste and oral care compositions with improved taste.
UY29404A1 (en) BETA-D CRYSTALINE FORM OF IVABRADINE CHLORHYDRATE, ITS PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.
UY29406A1 (en) GAMMA CRYSTAL FORM OF IVABRADINE CHLORHYDRATE, ITS PREPARATION PROCEDURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.
UA105911C2 (en) Sulfonamide derivatives
TN2012000126A1 (en) Polycyclic compounds as lysophosphatidic acid receptor antagonists
UA96076C2 (en) Use of trans-clomiphene
SG165417A1 (en) Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
TW200637609A (en) Oxidation resistant dentifrice compositions
TNSN07360A1 (en) Substituted pyrrolo-pyridines, composition containing them, method for their producing and use thereof
UA104869C2 (en) Normal;heading 1;heading 2;heading 3;PHARMACEUTICAL FORMULATIONS CONTAINING DOPAMINE RECEPTOR LIGANDS
PT2421879E (en) Novel 7-deazapurine nucleosides for therapeutic uses
MY151295A (en) Pyrimidyl indoline compound
MX2009005413A (en) Crystalline forms of zoledronic acid.
MX2009009153A (en) Pyrano-pyrazole-amines.
MY150829A (en) Oral compositions containing extracts of myristica fragrans and related methods
MX2009009291A (en) Radio fluoridation methods.
MX2009012472A (en) Combination comprising pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, and use thereof in the treatment of atopic dermatitis.
MX2007006042A (en) Bengamides with a substituted caprolactame cycle, method for the preparation thereof, compositions containing them and use thereof.
UA99146C2 (en) Co-crystals of pyrimethanil and dithianon, processes for their preparation (variants), a composition comprising them and its use, an aqueous suspension concentrate and processes for its preparation (variants)
MX2012001921A (en) Single diastereomers of 4-fluoroglutamine and methods fo their preparation and use.
MY152018A (en) Indole derivatives as anticancer agents
TN2010000585A1 (en) Pharmaceutical compositions of rosuvastatin calcium