HRP20120349T1 - Formulacija glatiramer acetata smanjenog volumenai postupci davanja - Google Patents
Formulacija glatiramer acetata smanjenog volumenai postupci davanja Download PDFInfo
- Publication number
- HRP20120349T1 HRP20120349T1 HRP20120349AT HRP20120349T HRP20120349T1 HR P20120349 T1 HRP20120349 T1 HR P20120349T1 HR P20120349A T HRP20120349A T HR P20120349AT HR P20120349 T HRP20120349 T HR P20120349T HR P20120349 T1 HRP20120349 T1 HR P20120349T1
- Authority
- HR
- Croatia
- Prior art keywords
- unit dose
- dose according
- injection
- subcutaneous injection
- glatiramer acetate
- Prior art date
Links
- 108010072051 Glatiramer Acetate Proteins 0.000 title claims abstract 9
- FHEAIOHRHQGZPC-KIWGSFCNSA-N acetic acid;(2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound CC(O)=O.C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 FHEAIOHRHQGZPC-KIWGSFCNSA-N 0.000 title claims abstract 9
- 229960003776 glatiramer acetate Drugs 0.000 title claims abstract 9
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003186 pharmaceutical solution Substances 0.000 claims abstract 9
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract 7
- 229930195725 Mannitol Natural products 0.000 claims abstract 7
- 235000010355 mannitol Nutrition 0.000 claims abstract 7
- 239000000594 mannitol Substances 0.000 claims abstract 7
- 239000000243 solution Substances 0.000 claims abstract 2
- 238000010254 subcutaneous injection Methods 0.000 claims 12
- 239000007929 subcutaneous injection Substances 0.000 claims 12
- 206010022095 Injection Site reaction Diseases 0.000 claims 7
- 238000002347 injection Methods 0.000 claims 5
- 239000007924 injection Substances 0.000 claims 5
- 230000000007 visual effect Effects 0.000 claims 4
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 1
- 229940071643 prefilled syringe Drugs 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27100909P | 2009-07-15 | 2009-07-15 | |
| US27134009P | 2009-07-20 | 2009-07-20 | |
| US33701110P | 2010-01-29 | 2010-01-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120349T1 true HRP20120349T1 (hr) | 2012-07-31 |
Family
ID=42283140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120349AT HRP20120349T1 (hr) | 2009-07-15 | 2012-04-18 | Formulacija glatiramer acetata smanjenog volumenai postupci davanja |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US20110060279A1 (da) |
| EP (2) | EP2275086B1 (da) |
| JP (1) | JP2012533540A (da) |
| AR (1) | AR077484A1 (da) |
| AT (1) | ATE549013T1 (da) |
| AU (1) | AU2010273234A1 (da) |
| BR (1) | BR112012000878A2 (da) |
| CA (1) | CA2697570C (da) |
| DK (1) | DK2275086T3 (da) |
| EA (1) | EA201270167A1 (da) |
| ES (1) | ES2383347T3 (da) |
| HK (1) | HK1152249A1 (da) |
| HR (1) | HRP20120349T1 (da) |
| IL (1) | IL217240A0 (da) |
| MX (1) | MX2012000687A (da) |
| PL (1) | PL2275086T3 (da) |
| PT (1) | PT2275086E (da) |
| RS (1) | RS52367B (da) |
| WO (1) | WO2011008274A2 (da) |
| ZA (1) | ZA201200586B (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| US12097357B2 (en) | 2008-09-15 | 2024-09-24 | West Pharma. Services IL, Ltd. | Stabilized pen injector |
| PT2275086E (pt) | 2009-07-15 | 2012-05-18 | Teva Pharma | Formulação de volume reduzido de acetato de glatirâmero e métodos de administração |
| US8920373B2 (en) | 2009-07-15 | 2014-12-30 | Teva Pharmaceutical Industries, Ltd. | Reduced volume formulation of glatiramer acetate and methods of administration |
| DK2630962T3 (da) | 2009-08-20 | 2018-07-23 | Yeda Res & Development Company Ltd | Lavfrekvent glatiramer-acetat-terapi |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| KR20140019296A (ko) | 2010-10-11 | 2014-02-14 | 테바 파마슈티컬 인더스트리즈 리미티드 | 글라티라머 아세테이트에 대한 임상 반응의 예측성 바이오마커로서의 사이토카인 바이오마커 |
| US8815511B2 (en) | 2011-10-10 | 2014-08-26 | Teva Pharmaceutical Industries, Ltd. | Determination of single nucleotide polymorphisms useful to predict response for glatiramer acetate |
| JP6510408B2 (ja) * | 2012-08-20 | 2019-05-08 | ケアベイ・ヨーロッパ・リミテッドＣａｒｅｂａｙ Ｅｕｒｏｐｅ Ｌｉｍｉｔｅｄ | 自動注射器具 |
| CA2884267A1 (en) | 2012-10-10 | 2014-04-17 | Teva Pharmaceutical Industries Ltd. | Biomarkers predictive for clinical response for glatiramer acetate |
| WO2014128079A1 (en) * | 2013-02-19 | 2014-08-28 | Synthon B.V. | Glatiramer acetate multidose formulation |
| BR112015021548A2 (pt) * | 2013-03-08 | 2017-07-18 | Teva Pharmaceutical Industries Ltd | dispositivo injetor reutilizável para seringa |
| US8591463B1 (en) * | 2013-03-08 | 2013-11-26 | Teva Pharmaceutical Industries Ltd. | Re-useable injector device for syringe |
| NZ630468A (en) * | 2013-03-08 | 2017-04-28 | Teva Pharma | Re-useable injector device for syringe |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| CA2939651A1 (en) | 2014-02-26 | 2015-09-03 | Allergan, Inc. | Intraocular implant delivery apparatus and methods of use thereof |
| US9415176B1 (en) | 2015-01-22 | 2016-08-16 | West Pharmaceutical Services, Inc. | Autoinjector having an end-of-dose visual indicator |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| EP3534893A1 (en) * | 2016-11-02 | 2019-09-11 | To Pharmaceuticals LLC | Combination therapy of cbd and copaxone |
| CN110402097A (zh) | 2016-12-07 | 2019-11-01 | 普罗根尼蒂公司 | 胃肠道检测方法、装置和系统 |
| JP7602322B2 (ja) | 2017-03-26 | 2024-12-18 | マピ ファーマ リミテッド | 進行型の多発性硬化症を治療するためのグラチラマーデポシステム |
| EP3645029B1 (en) | 2017-06-26 | 2023-01-18 | Institut Pasteur | Treatments to eliminate hiv reservoirs and reduce viral load |
| US20200306516A1 (en) | 2017-08-14 | 2020-10-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2017924B3 (es) * | 1985-10-11 | 1991-03-16 | Duphar Int Res B V | Inyector automatico. |
| NL8701091A (nl) * | 1987-05-08 | 1988-12-01 | Spruyt Hillen Bv | Injectiepen. |
| US5981485A (en) * | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
| GB8926825D0 (en) * | 1989-11-28 | 1990-01-17 | Glaxo Group Ltd | Device |
| IL113812A (en) * | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
| US6454746B1 (en) * | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
| US20020077278A1 (en) * | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
| SE518981C2 (sv) | 2000-12-14 | 2002-12-17 | Shl Medical Ab | Autoinjektor |
| CN100464796C (zh) * | 2002-11-25 | 2009-03-04 | 特克法马许可公司 | 包括可复位安全释放设备的自动注射器 |
| US7585843B2 (en) * | 2003-10-03 | 2009-09-08 | Bayhill Therapeutics, Inc. | Treatment of demyelinating autoimmune disease with modified ordered peptides |
| US7655221B2 (en) * | 2004-05-07 | 2010-02-02 | Peptimmune, Inc. | Methods of treating disease with random copolymers |
| US20090048181A1 (en) * | 2004-09-02 | 2009-02-19 | Schipper Hyman M | Combination therapy with glatiramer acetate and n-acetylcysteine for the treatment of multiple sclerosis |
| WO2006029411A2 (en) * | 2004-09-09 | 2006-03-16 | Yeda Research And Development Co. Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof |
| AU2005302500B2 (en) * | 2004-10-29 | 2008-11-27 | Sandoz Ag | Processes for preparing glatiramer |
| US20070161566A1 (en) * | 2006-01-11 | 2007-07-12 | Teva Pharmaceutical Industries, Ltd. | Method of treating multiple sclerosis |
| US20070161960A1 (en) * | 2006-01-12 | 2007-07-12 | Fu-Yuan Li | Lancet device |
| US20080118553A1 (en) * | 2006-06-12 | 2008-05-22 | Anton Frenkel | Tannate salt form of polypeptide mixtures, their preparation and use |
| BRPI0713802A2 (pt) * | 2006-06-30 | 2012-11-06 | Abbott Biotech Ltd | dispositivo de injeção automático |
| USD622374S1 (en) * | 2006-09-06 | 2010-08-24 | Abbott Biotechnology Ltd. | Automatic injection device |
| WO2009070298A1 (en) | 2007-11-28 | 2009-06-04 | Teva Pharmaceutical Industries, Ltd. | Method of delaying the onset of clinically definite multiple sclerosis |
| USD607558S1 (en) * | 2008-09-19 | 2010-01-05 | Becton Dickinson France S.A.S. | Medicine injector |
| PT2275086E (pt) * | 2009-07-15 | 2012-05-18 | Teva Pharma | Formulação de volume reduzido de acetato de glatirâmero e métodos de administração |
-
2010
- 2010-04-15 PT PT10160099T patent/PT2275086E/pt unknown
- 2010-04-15 RS RS20120188A patent/RS52367B/en unknown
- 2010-04-15 CA CA2697570A patent/CA2697570C/en not_active Expired - Fee Related
- 2010-04-15 EP EP10160099A patent/EP2275086B1/en active Active
- 2010-04-15 PL PL10160099T patent/PL2275086T3/pl unknown
- 2010-04-15 DK DK10160099.7T patent/DK2275086T3/da active
- 2010-04-15 ES ES10160099T patent/ES2383347T3/es active Active
- 2010-04-15 US US12/761,367 patent/US20110060279A1/en not_active Abandoned
- 2010-04-15 AT AT10160099T patent/ATE549013T1/de active
- 2010-05-21 US US12/785,125 patent/US7855176B1/en not_active Expired - Fee Related
- 2010-07-14 EP EP10800156A patent/EP2453907A2/en not_active Withdrawn
- 2010-07-14 JP JP2012520598A patent/JP2012533540A/ja active Pending
- 2010-07-14 WO PCT/US2010/001972 patent/WO2011008274A2/en active Application Filing
- 2010-07-14 MX MX2012000687A patent/MX2012000687A/es not_active Application Discontinuation
- 2010-07-14 EA EA201270167A patent/EA201270167A1/ru unknown
- 2010-07-14 BR BR112012000878A patent/BR112012000878A2/pt not_active IP Right Cessation
- 2010-07-14 AU AU2010273234A patent/AU2010273234A1/en not_active Abandoned
- 2010-07-15 AR ARP100102598A patent/AR077484A1/es unknown
- 2010-11-17 US US12/948,611 patent/US9018170B2/en not_active Expired - Fee Related
-
2011
- 2011-06-22 HK HK11106439.3A patent/HK1152249A1/xx unknown
- 2011-12-27 IL IL217240A patent/IL217240A0/en unknown
-
2012
- 2012-01-24 ZA ZA2012/00586A patent/ZA201200586B/en unknown
- 2012-04-18 HR HRP20120349AT patent/HRP20120349T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2697570A1 (en) | 2010-06-22 |
| MX2012000687A (es) | 2012-09-07 |
| US9018170B2 (en) | 2015-04-28 |
| EP2275086B1 (en) | 2012-03-14 |
| WO2011008274A3 (en) | 2011-09-22 |
| ATE549013T1 (de) | 2012-03-15 |
| PT2275086E (pt) | 2012-05-18 |
| CA2697570C (en) | 2011-11-01 |
| US20110060279A1 (en) | 2011-03-10 |
| RS52367B (en) | 2012-12-31 |
| WO2011008274A2 (en) | 2011-01-20 |
| AU2010273234A1 (en) | 2012-02-23 |
| HK1152249A1 (en) | 2012-02-24 |
| AR077484A1 (es) | 2011-08-31 |
| US20110066112A1 (en) | 2011-03-17 |
| ZA201200586B (en) | 2013-10-30 |
| EP2275086A1 (en) | 2011-01-19 |
| IL217240A0 (en) | 2012-02-29 |
| PL2275086T3 (pl) | 2012-09-28 |
| EP2453907A2 (en) | 2012-05-23 |
| BR112012000878A2 (pt) | 2019-09-24 |
| US7855176B1 (en) | 2010-12-21 |
| DK2275086T3 (da) | 2012-07-09 |
| EA201270167A1 (ru) | 2012-08-30 |
| ES2383347T3 (es) | 2012-06-20 |
| WO2011008274A4 (en) | 2011-11-10 |
| JP2012533540A (ja) | 2012-12-27 |
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