HRP20090614T1 - Stabilizirane superzasićene krute otopine steroidnih lijekova - Google Patents

Stabilizirane superzasićene krute otopine steroidnih lijekova Download PDF

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Publication number
HRP20090614T1
HRP20090614T1 HR20090614T HRP20090614T HRP20090614T1 HR P20090614 T1 HRP20090614 T1 HR P20090614T1 HR 20090614 T HR20090614 T HR 20090614T HR P20090614 T HRP20090614 T HR P20090614T HR P20090614 T1 HRP20090614 T1 HR P20090614T1
Authority
HR
Croatia
Prior art keywords
steroid molecule
solvent
acetate
steroid
drospirenone
Prior art date
Application number
HR20090614T
Other languages
English (en)
Croatian (hr)
Inventor
Funke Adrian
Wagner Torsten
Lipp Ralph
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34928105&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20090614(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of HRP20090614T1 publication Critical patent/HRP20090614T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
HR20090614T 2004-03-10 2005-03-10 Stabilizirane superzasićene krute otopine steroidnih lijekova HRP20090614T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55133004P 2004-03-10 2004-03-10
EP04075714 2004-03-10
PCT/IB2005/000748 WO2005087199A2 (en) 2004-03-10 2005-03-10 Stabilised supersaturated solid solutions of steroidal drugs

Publications (1)

Publication Number Publication Date
HRP20090614T1 true HRP20090614T1 (hr) 2009-12-31

Family

ID=34928105

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090614T HRP20090614T1 (hr) 2004-03-10 2005-03-10 Stabilizirane superzasićene krute otopine steroidnih lijekova

Country Status (32)

Country Link
US (1) US8715735B2 (enExample)
EP (2) EP1765290B1 (enExample)
JP (1) JP5006185B2 (enExample)
KR (1) KR101210695B1 (enExample)
CN (1) CN1984644B (enExample)
AR (1) AR048500A1 (enExample)
AT (1) ATE442131T1 (enExample)
AU (1) AU2005221403B8 (enExample)
BR (1) BRPI0507342A (enExample)
CA (1) CA2558582C (enExample)
CR (1) CR8630A (enExample)
DE (1) DE602005016551D1 (enExample)
DK (1) DK1765290T3 (enExample)
EA (1) EA012746B1 (enExample)
EC (1) ECSP066902A (enExample)
ES (2) ES2332229T3 (enExample)
GT (1) GT200500045A (enExample)
HR (1) HRP20090614T1 (enExample)
IL (1) IL177894A0 (enExample)
MY (1) MY142989A (enExample)
NO (1) NO20064473L (enExample)
NZ (1) NZ549793A (enExample)
PA (1) PA8626101A1 (enExample)
PE (1) PE20060016A1 (enExample)
PL (1) PL1765290T3 (enExample)
PT (1) PT1765290E (enExample)
RS (1) RS51076B (enExample)
SI (1) SI1765290T1 (enExample)
SV (1) SV2005002044A (enExample)
TW (1) TWI345986B (enExample)
UY (1) UY28803A1 (enExample)
WO (1) WO2005087199A2 (enExample)

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Also Published As

Publication number Publication date
MY142989A (en) 2011-02-14
WO2005087199A2 (en) 2005-09-22
KR20060132999A (ko) 2006-12-22
ATE442131T1 (de) 2009-09-15
NO20064473L (no) 2006-10-10
DE602005016551D1 (de) 2009-10-22
CA2558582C (en) 2013-07-16
PE20060016A1 (es) 2006-02-16
RS51076B (sr) 2010-10-31
WO2005087199A8 (en) 2007-03-29
ECSP066902A (es) 2006-12-20
EA012746B1 (ru) 2009-12-30
PL1765290T3 (pl) 2010-02-26
CA2558582A1 (en) 2005-09-22
CR8630A (es) 2007-06-06
AR048500A1 (es) 2006-05-03
EP2087883B1 (en) 2012-07-25
NZ549793A (en) 2010-06-25
AU2005221403B8 (en) 2010-01-07
TW200600116A (en) 2006-01-01
AU2005221403B2 (en) 2009-12-10
IL177894A0 (en) 2006-12-31
EA200601588A1 (ru) 2007-02-27
DK1765290T3 (da) 2009-11-02
ES2390406T3 (es) 2012-11-12
ES2332229T3 (es) 2010-01-29
EP2087883A1 (en) 2009-08-12
SI1765290T1 (sl) 2010-01-29
US8715735B2 (en) 2014-05-06
CN1984644B (zh) 2010-12-08
PT1765290E (pt) 2009-11-23
EP1765290B1 (en) 2009-09-09
HK1103660A1 (en) 2007-12-28
PA8626101A1 (es) 2006-07-03
GT200500045A (es) 2005-10-31
JP5006185B2 (ja) 2012-08-22
TWI345986B (en) 2011-08-01
EP1765290A2 (en) 2007-03-28
US20050207990A1 (en) 2005-09-22
SV2005002044A (es) 2005-11-04
AU2005221403A1 (en) 2005-09-22
BRPI0507342A (pt) 2007-07-03
UY28803A1 (es) 2005-10-31
CN1984644A (zh) 2007-06-20
KR101210695B1 (ko) 2012-12-11
JP2007528389A (ja) 2007-10-11
WO2005087199A3 (en) 2009-01-15

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