HRP20090302T1 - New macrolides - Google Patents
New macrolidesInfo
- Publication number
- HRP20090302T1 HRP20090302T1 HR20090302T HRP20090302T HRP20090302T1 HR P20090302 T1 HRP20090302 T1 HR P20090302T1 HR 20090302 T HR20090302 T HR 20090302T HR P20090302 T HRP20090302 T HR P20090302T HR P20090302 T1 HRP20090302 T1 HR P20090302T1
- Authority
- HR
- Croatia
- Prior art keywords
- group
- atoms
- sulfur
- atom
- carbon
- Prior art date
Links
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 2
- 229940041033 macrolides Drugs 0.000 title 1
- 125000004429 atom Chemical group 0.000 abstract 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 229910052717 sulfur Inorganic materials 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 239000011593 sulfur Substances 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyano, nitro, amino Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05002664 | 2005-02-09 | ||
| EP05011419 | 2005-05-26 | ||
| PCT/CH2006/000083 WO2006084410A1 (en) | 2005-02-09 | 2006-02-08 | New macrolides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090302T1 true HRP20090302T1 (en) | 2009-07-31 |
Family
ID=36204543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090302T HRP20090302T1 (en) | 2005-02-09 | 2009-05-22 | New macrolides |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7524823B2 (de) |
| EP (1) | EP1846430B1 (de) |
| JP (1) | JP5112079B2 (de) |
| KR (1) | KR101139751B1 (de) |
| AT (1) | ATE427315T1 (de) |
| AU (1) | AU2006212626B2 (de) |
| CA (1) | CA2597327C (de) |
| CY (1) | CY1109187T1 (de) |
| DE (1) | DE602006006030D1 (de) |
| DK (1) | DK1846430T3 (de) |
| ES (1) | ES2322775T3 (de) |
| HR (1) | HRP20090302T1 (de) |
| MX (1) | MX2007008549A (de) |
| PL (1) | PL1846430T3 (de) |
| SI (1) | SI1846430T1 (de) |
| TW (1) | TWI389916B (de) |
| WO (1) | WO2006084410A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2428874T3 (es) * | 2006-08-09 | 2013-11-12 | Basilea Pharmaceutica Ag | Nuevos macrólidos útiles contra las enfermedades inflamatorias y alérgicas |
| EP2056844A4 (de) * | 2006-08-24 | 2010-11-24 | Wockhardt Research Center | Neue makrolide und ketolide mit antimikrobieller wirkung |
| WO2009098320A2 (en) | 2008-02-08 | 2009-08-13 | Basilea Pharmaceutica Ag | Macrolides and uses of macrolides |
| BRPI0908343A2 (pt) * | 2008-02-08 | 2020-08-18 | Basilea Pharmaceutica Ag | macrolídeos e seu uso |
| WO2009130189A1 (en) * | 2008-04-23 | 2009-10-29 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | 2'-o,3'-n-bridged macrolides |
| WO2010136971A1 (en) * | 2009-05-27 | 2010-12-02 | Wockhardt Research Centre | Ketolide compounds having antimicrobial activity |
| JP5662445B2 (ja) * | 2009-08-13 | 2015-01-28 | バジリア ファルマスーチカ アーゲーＢａｓｉｌｅａ Ｐｈａｒｍａｃｅｕｔｉｃａ ＡＧ | 新規マクロライド及びその使用 |
| PT2938623T (pt) * | 2012-12-31 | 2016-11-23 | Basilea Pharmaceutica Ag | Macrólidos selecionados com atividade inibitória de pde4 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1313751B1 (de) * | 2000-08-22 | 2008-09-17 | Basilea Pharmaceutica AG | Neue macrolide mit antibakterieller wirkung |
| CA2451391A1 (en) * | 2001-07-03 | 2003-01-16 | Chiron Corporation | C12 modified erythromycin macrolides and ketolides having antibacterial activity |
| EP1471923A4 (de) * | 2002-01-17 | 2006-01-11 | Kosan Biosciences Inc | Amido-makrolide |
| US6995143B2 (en) * | 2002-02-28 | 2006-02-07 | Basilea Pharmaceutica Ag | Macrolides with antibacterial activity |
| DE102004002638A1 (de) | 2004-01-19 | 2005-08-18 | Merck Patent Gmbh | Kombinationen von Serotonin-Wiederaufnahme-Hemmern und Imidazolin-I2-Agonisten |
-
2006
- 2006-02-08 PL PL06701650T patent/PL1846430T3/pl unknown
- 2006-02-08 SI SI200630285T patent/SI1846430T1/sl unknown
- 2006-02-08 KR KR1020077018855A patent/KR101139751B1/ko not_active IP Right Cessation
- 2006-02-08 AT AT06701650T patent/ATE427315T1/de active
- 2006-02-08 CA CA2597327A patent/CA2597327C/en not_active Expired - Fee Related
- 2006-02-08 JP JP2007554411A patent/JP5112079B2/ja not_active Expired - Fee Related
- 2006-02-08 EP EP06701650A patent/EP1846430B1/de active Active
- 2006-02-08 DK DK06701650T patent/DK1846430T3/da active
- 2006-02-08 TW TW095104242A patent/TWI389916B/zh not_active IP Right Cessation
- 2006-02-08 ES ES06701650T patent/ES2322775T3/es active Active
- 2006-02-08 DE DE602006006030T patent/DE602006006030D1/de active Active
- 2006-02-08 MX MX2007008549A patent/MX2007008549A/es active IP Right Grant
- 2006-02-08 WO PCT/CH2006/000083 patent/WO2006084410A1/en active Application Filing
- 2006-02-08 AU AU2006212626A patent/AU2006212626B2/en not_active Ceased
- 2006-05-08 US US11/429,678 patent/US7524823B2/en not_active Expired - Fee Related
-
2009
- 2009-05-22 HR HR20090302T patent/HRP20090302T1/xx unknown
- 2009-06-29 CY CY20091100676T patent/CY1109187T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2597327A1 (en) | 2006-08-17 |
| DE602006006030D1 (de) | 2009-05-14 |
| PL1846430T3 (pl) | 2009-08-31 |
| AU2006212626A1 (en) | 2006-08-17 |
| TWI389916B (zh) | 2013-03-21 |
| AU2006212626B2 (en) | 2010-04-29 |
| JP5112079B2 (ja) | 2013-01-09 |
| ES2322775T3 (es) | 2009-06-26 |
| MX2007008549A (es) | 2007-08-14 |
| KR101139751B1 (ko) | 2012-04-26 |
| TW200640942A (en) | 2006-12-01 |
| EP1846430B1 (de) | 2009-04-01 |
| ATE427315T1 (de) | 2009-04-15 |
| SI1846430T1 (sl) | 2009-08-31 |
| EP1846430A1 (de) | 2007-10-24 |
| JP2008530035A (ja) | 2008-08-07 |
| CA2597327C (en) | 2012-02-07 |
| KR20070113206A (ko) | 2007-11-28 |
| US20060264387A1 (en) | 2006-11-23 |
| WO2006084410A1 (en) | 2006-08-17 |
| US7524823B2 (en) | 2009-04-28 |
| DK1846430T3 (da) | 2009-06-22 |
| CY1109187T1 (el) | 2014-07-02 |
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