HRP20040744A2 - Preparation of n-methyl-3-hydroxy-3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediates - Google Patents
Preparation of n-methyl-3-hydroxy-3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediatesInfo
- Publication number
- HRP20040744A2 HRP20040744A2 HRP20040744A HRP20040744A2 HR P20040744 A2 HRP20040744 A2 HR P20040744A2 HR P20040744 A HRP20040744 A HR P20040744A HR P20040744 A2 HRP20040744 A2 HR P20040744A2
- Authority
- HR
- Croatia
- Prior art keywords
- thienyl
- intermediates
- hydroxy
- methyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10207586A DE10207586A1 (de) | 2002-02-22 | 2002-02-22 | Herstellung von N-Methyl-3-hydroxy-3-(2-thienyl)propanamin über neue carbamatgruppenhaltige Thiophenderivate als Zwischenprodukte |
PCT/EP2003/000910 WO2003070720A1 (en) | 2002-02-22 | 2003-01-30 | Preparation of n-methyl-3-hydroxy- 3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20040744A2 true HRP20040744A2 (en) | 2004-12-31 |
Family
ID=27740334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20040744 HRP20040744A2 (en) | 2002-02-22 | 2004-08-18 | Preparation of n-methyl-3-hydroxy-3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediates |
Country Status (11)
Country | Link |
---|---|
US (1) | US20050171360A1 (xx) |
EP (1) | EP1476439A1 (xx) |
JP (1) | JP2005519077A (xx) |
KR (1) | KR20040096593A (xx) |
AU (1) | AU2003206800A1 (xx) |
CA (1) | CA2477082A1 (xx) |
DE (1) | DE10207586A1 (xx) |
HR (1) | HRP20040744A2 (xx) |
IL (1) | IL163611A0 (xx) |
PL (1) | PL370432A1 (xx) |
WO (1) | WO2003070720A1 (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1506965A4 (en) * | 2002-05-20 | 2010-11-03 | Mitsubishi Rayon Co | PROPANOLAMINE DERIVATIVES, PROCESS FOR THE PREPARATION OF 3-N-METHYLAMINO-1- (2-THIENYL) -1-PROPANOLS AND PROCESS FOR THE PREPARATION OF PROPANOLAMINE DERIVATIVES |
WO2005080370A1 (en) * | 2004-02-19 | 2005-09-01 | Lonza Ag | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols |
EP1566383A1 (en) * | 2004-02-19 | 2005-08-24 | Lonza AG | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols |
CZ297560B6 (cs) * | 2004-10-26 | 2007-02-07 | Zentiva, A. S. | Zpusob výroby hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu (duloxetinu) |
CA2599475A1 (en) | 2005-03-14 | 2006-09-21 | Teva Pharmaceutical Industries Ltd. | Pure duloxetine hydrochloride |
WO2006104249A1 (ja) * | 2005-03-29 | 2006-10-05 | Zeon Corporation | 1−(2−チエニル)−3−アルキルアミノプロピルアルコールの製造方法 |
MY148074A (en) | 2005-05-10 | 2013-02-28 | Novartis Ag | Pharmaceutical compositions comprising imatinib and a release retardant |
EP1838692A2 (en) | 2005-09-22 | 2007-10-03 | Teva Pharmaceutical Industries Ltd | Dnt-maleate and methods of preparation thereof |
US20080015362A1 (en) * | 2006-04-17 | 2008-01-17 | Santiago Ini | Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine |
TW200813002A (en) * | 2006-05-31 | 2008-03-16 | Teva Pharma | Process for preparing duloxetine and intermediates thereof |
WO2008004191A2 (en) | 2006-07-03 | 2008-01-10 | Ranbaxy Laboratories Limited | Process for the preparation of enantiomerically pure salts of n-methyl-3- ( 1-naphthaleneoxy) -3- (2-thienyl) propanamine |
EP2114912B1 (en) * | 2006-12-22 | 2012-04-04 | Synthon B.V. | Process for making duloxetine and related compounds |
US8148549B2 (en) * | 2009-03-12 | 2012-04-03 | Sci Pharmtech, Inc. | Preparation of (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl) propylamine using optically active methylhydroxylaminopropanol compound as an intermediate |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI912280A (fi) * | 1990-05-17 | 1991-11-18 | Lilly Co Eli | Kiral syntes av 1-aryl-3-aminopropan-1 -oler. |
-
2002
- 2002-02-22 DE DE10207586A patent/DE10207586A1/de not_active Ceased
-
2003
- 2003-01-30 AU AU2003206800A patent/AU2003206800A1/en not_active Abandoned
- 2003-01-30 US US10/503,600 patent/US20050171360A1/en not_active Abandoned
- 2003-01-30 JP JP2003569627A patent/JP2005519077A/ja active Pending
- 2003-01-30 EP EP03704496A patent/EP1476439A1/en not_active Withdrawn
- 2003-01-30 KR KR10-2004-7012990A patent/KR20040096593A/ko not_active Application Discontinuation
- 2003-01-30 IL IL16361103A patent/IL163611A0/xx unknown
- 2003-01-30 PL PL03370432A patent/PL370432A1/xx not_active Application Discontinuation
- 2003-01-30 WO PCT/EP2003/000910 patent/WO2003070720A1/en not_active Application Discontinuation
- 2003-01-30 CA CA002477082A patent/CA2477082A1/en not_active Abandoned
-
2004
- 2004-08-18 HR HRP20040744 patent/HRP20040744A2/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1476439A1 (en) | 2004-11-17 |
US20050171360A1 (en) | 2005-08-04 |
JP2005519077A (ja) | 2005-06-30 |
PL370432A1 (en) | 2005-05-30 |
WO2003070720A1 (en) | 2003-08-28 |
DE10207586A1 (de) | 2003-09-11 |
IL163611A0 (en) | 2005-12-18 |
CA2477082A1 (en) | 2003-08-28 |
AU2003206800A1 (en) | 2003-09-09 |
KR20040096593A (ko) | 2004-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20050103 Year of fee payment: 3 |
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OBST | Application withdrawn |