HRP20020262B1 - Substituted pyrroles as antiproliferative agents for the treatment of cancer - Google Patents

Substituted pyrroles as antiproliferative agents for the treatment of cancer

Info

Publication number
HRP20020262B1
HRP20020262B1 HR20020262A HRP20020262A HRP20020262B1 HR P20020262 B1 HRP20020262 B1 HR P20020262B1 HR 20020262 A HR20020262 A HR 20020262A HR P20020262 A HRP20020262 A HR P20020262A HR P20020262 B1 HRP20020262 B1 HR P20020262B1
Authority
HR
Croatia
Prior art keywords
cancer
treatment
antiproliferative agents
substituted pyrroles
pyrroles
Prior art date
Application number
HR20020262A
Other languages
English (en)
Inventor
Fotouhi Nader
Kong Norman
Emily
Allen
John
Original Assignee
F. Hoffmann - La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann - La Roche Ag filed Critical F. Hoffmann - La Roche Ag
Publication of HRP20020262A2 publication Critical patent/HRP20020262A2/xx
Publication of HRP20020262B1 publication Critical patent/HRP20020262B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20020262A 1999-10-12 2002-03-27 Substituted pyrroles as antiproliferative agents for the treatment of cancer HRP20020262B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15886099P 1999-10-12 1999-10-12
PCT/EP2000/009635 WO2001027106A1 (en) 1999-10-12 2000-10-02 Substituted pyrroles as antiproliferative agents for the treatment of cancer

Publications (2)

Publication Number Publication Date
HRP20020262A2 HRP20020262A2 (en) 2004-04-30
HRP20020262B1 true HRP20020262B1 (en) 2005-06-30

Family

ID=22570037

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020262A HRP20020262B1 (en) 1999-10-12 2002-03-27 Substituted pyrroles as antiproliferative agents for the treatment of cancer

Country Status (30)

Country Link
EP (1) EP1224181B1 (hu)
JP (1) JP2003511449A (hu)
KR (1) KR20020038817A (hu)
CN (1) CN1155595C (hu)
AR (1) AR026004A1 (hu)
AT (1) ATE255576T1 (hu)
AU (1) AU781732B2 (hu)
BR (1) BR0014680A (hu)
CA (1) CA2385071A1 (hu)
CZ (1) CZ20021610A3 (hu)
DE (1) DE60006990T2 (hu)
DK (1) DK1224181T3 (hu)
ES (1) ES2210005T3 (hu)
HK (1) HK1050533A1 (hu)
HR (1) HRP20020262B1 (hu)
HU (1) HUP0203558A3 (hu)
IL (1) IL148815A0 (hu)
MA (1) MA26830A1 (hu)
MX (1) MXPA02003667A (hu)
NO (1) NO20021718D0 (hu)
NZ (1) NZ518038A (hu)
PE (1) PE20010695A1 (hu)
PL (1) PL357441A1 (hu)
PT (1) PT1224181E (hu)
RU (1) RU2002110111A (hu)
TR (1) TR200200987T2 (hu)
TW (1) TWI230708B (hu)
WO (1) WO2001027106A1 (hu)
YU (1) YU25202A (hu)
ZA (1) ZA200202231B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313143B1 (en) * 1999-12-16 2001-11-06 Hoffmann-La Roche Inc. Substituted pyrroles
US7776855B2 (en) 2006-07-27 2010-08-17 Janssen Pharmaceutica N.V. Antimicrobial oxazolidinone prodrugs
AU2010266040B2 (en) * 2009-06-25 2015-01-15 Alkermes Pharma Ireland Limited Prodrugs of NH-acidic compounds
UY34072A (es) * 2011-05-17 2013-01-03 Novartis Ag Derivados sustituidos de indol
US20150284364A1 (en) 2012-11-07 2015-10-08 Nicole Bieri Substituted indole derivatives
EP3771711A1 (en) 2019-07-29 2021-02-03 Bayer Animal Health GmbH Pyrazole derivatives for controlling arthropods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
PE91598A1 (es) * 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
PT1064279E (pt) * 1998-03-17 2003-10-31 Hoffmann La Roche Bisindolilmaleimidas substituidas para a inibicao da proliferacao celular

Also Published As

Publication number Publication date
ATE255576T1 (de) 2003-12-15
NO20021718L (no) 2002-04-11
EP1224181A1 (en) 2002-07-24
MXPA02003667A (es) 2002-08-30
AR026004A1 (es) 2002-12-26
IL148815A0 (en) 2002-09-12
YU25202A (sh) 2004-12-31
JP2003511449A (ja) 2003-03-25
TR200200987T2 (tr) 2002-09-23
PL357441A1 (en) 2004-07-26
NO20021718D0 (no) 2002-04-11
PE20010695A1 (es) 2001-07-05
CN1378545A (zh) 2002-11-06
AU7911600A (en) 2001-04-23
DE60006990D1 (de) 2004-01-15
BR0014680A (pt) 2002-06-11
HK1050533A1 (en) 2003-06-27
AU781732B2 (en) 2005-06-09
KR20020038817A (ko) 2002-05-23
MA26830A1 (fr) 2004-12-20
DK1224181T3 (da) 2004-04-13
EP1224181B1 (en) 2003-12-03
NZ518038A (en) 2004-02-27
CZ20021610A3 (cs) 2002-10-16
HUP0203558A3 (en) 2004-01-28
PT1224181E (pt) 2004-04-30
RU2002110111A (ru) 2003-12-20
HRP20020262A2 (en) 2004-04-30
CA2385071A1 (en) 2001-04-19
DE60006990T2 (de) 2004-10-28
WO2001027106A1 (en) 2001-04-19
ES2210005T3 (es) 2004-07-01
HUP0203558A2 (hu) 2003-02-28
CN1155595C (zh) 2004-06-30
ZA200202231B (en) 2003-06-19
TWI230708B (en) 2005-04-11

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20050516

Year of fee payment: 6

B1PR Patent granted
PBON Lapse due to non-payment of renewal fee

Effective date: 20061003