DE60006990D1 - Pyrrolderivate mit antiproliferativer wirkung geeignet für die behandlung von krebs - Google Patents

Pyrrolderivate mit antiproliferativer wirkung geeignet für die behandlung von krebs

Info

Publication number
DE60006990D1
DE60006990D1 DE60006990T DE60006990T DE60006990D1 DE 60006990 D1 DE60006990 D1 DE 60006990D1 DE 60006990 T DE60006990 T DE 60006990T DE 60006990 T DE60006990 T DE 60006990T DE 60006990 D1 DE60006990 D1 DE 60006990D1
Authority
DE
Germany
Prior art keywords
cancer
treatment
antiproliferative effect
effect suitable
pyrrol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60006990T
Other languages
English (en)
Other versions
DE60006990T2 (de
Inventor
Nader Fotouhi
Norman Kong
Aijun Liu
John Lovey
Guilfoyle Mullin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60006990D1 publication Critical patent/DE60006990D1/de
Application granted granted Critical
Publication of DE60006990T2 publication Critical patent/DE60006990T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60006990T 1999-10-12 2000-10-02 Pyrrolderivate mit antiproliferativer wirkung geeignet für die behandlung von krebs Expired - Fee Related DE60006990T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15886099P 1999-10-12 1999-10-12
US158860P 1999-10-12
PCT/EP2000/009635 WO2001027106A1 (en) 1999-10-12 2000-10-02 Substituted pyrroles as antiproliferative agents for the treatment of cancer

Publications (2)

Publication Number Publication Date
DE60006990D1 true DE60006990D1 (de) 2004-01-15
DE60006990T2 DE60006990T2 (de) 2004-10-28

Family

ID=22570037

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006990T Expired - Fee Related DE60006990T2 (de) 1999-10-12 2000-10-02 Pyrrolderivate mit antiproliferativer wirkung geeignet für die behandlung von krebs

Country Status (30)

Country Link
EP (1) EP1224181B1 (de)
JP (1) JP2003511449A (de)
KR (1) KR20020038817A (de)
CN (1) CN1155595C (de)
AR (1) AR026004A1 (de)
AT (1) ATE255576T1 (de)
AU (1) AU781732B2 (de)
BR (1) BR0014680A (de)
CA (1) CA2385071A1 (de)
CZ (1) CZ20021610A3 (de)
DE (1) DE60006990T2 (de)
DK (1) DK1224181T3 (de)
ES (1) ES2210005T3 (de)
HK (1) HK1050533A1 (de)
HR (1) HRP20020262B1 (de)
HU (1) HUP0203558A3 (de)
IL (1) IL148815A0 (de)
MA (1) MA26830A1 (de)
MX (1) MXPA02003667A (de)
NO (1) NO20021718L (de)
NZ (1) NZ518038A (de)
PE (1) PE20010695A1 (de)
PL (1) PL357441A1 (de)
PT (1) PT1224181E (de)
RU (1) RU2002110111A (de)
TR (1) TR200200987T2 (de)
TW (1) TWI230708B (de)
WO (1) WO2001027106A1 (de)
YU (1) YU25202A (de)
ZA (1) ZA200202231B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313143B1 (en) * 1999-12-16 2001-11-06 Hoffmann-La Roche Inc. Substituted pyrroles
US7776855B2 (en) 2006-07-27 2010-08-17 Janssen Pharmaceutica N.V. Antimicrobial oxazolidinone prodrugs
WO2010151711A1 (en) * 2009-06-25 2010-12-29 Alkermes, Inc. Prodrugs of nh-acidic compounds
UY34072A (es) 2011-05-17 2013-01-03 Novartis Ag Derivados sustituidos de indol
IN2015DN02660A (de) 2012-11-07 2015-09-04 Novartis Ag
EP3771711A1 (de) 2019-07-29 2021-02-03 Bayer Animal Health GmbH Pyrazolderivate für die kontrolle von arthropoden

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
PE91598A1 (es) * 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
EP1064279B1 (de) * 1998-03-17 2003-06-25 F.Hoffmann-La Roche Ag Substituierte bisindolylmaleimide zur inhibierung der zellproliferation

Also Published As

Publication number Publication date
CA2385071A1 (en) 2001-04-19
DK1224181T3 (da) 2004-04-13
TR200200987T2 (tr) 2002-09-23
AR026004A1 (es) 2002-12-26
WO2001027106A1 (en) 2001-04-19
YU25202A (sh) 2004-12-31
NO20021718D0 (no) 2002-04-11
PL357441A1 (en) 2004-07-26
ES2210005T3 (es) 2004-07-01
ATE255576T1 (de) 2003-12-15
CN1378545A (zh) 2002-11-06
IL148815A0 (en) 2002-09-12
PT1224181E (pt) 2004-04-30
NO20021718L (no) 2002-04-11
AU7911600A (en) 2001-04-23
HRP20020262A2 (en) 2004-04-30
HRP20020262B1 (en) 2005-06-30
HK1050533A1 (en) 2003-06-27
ZA200202231B (en) 2003-06-19
PE20010695A1 (es) 2001-07-05
HUP0203558A2 (hu) 2003-02-28
EP1224181A1 (de) 2002-07-24
CZ20021610A3 (cs) 2002-10-16
NZ518038A (en) 2004-02-27
EP1224181B1 (de) 2003-12-03
JP2003511449A (ja) 2003-03-25
CN1155595C (zh) 2004-06-30
TWI230708B (en) 2005-04-11
MA26830A1 (fr) 2004-12-20
KR20020038817A (ko) 2002-05-23
HUP0203558A3 (en) 2004-01-28
BR0014680A (pt) 2002-06-11
MXPA02003667A (es) 2002-08-30
DE60006990T2 (de) 2004-10-28
AU781732B2 (en) 2005-06-09
RU2002110111A (ru) 2003-12-20

Similar Documents

Publication Publication Date Title
ATE286895T1 (de) Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten
DE60108754D1 (de) Substituierte bizyklische derivate für die behandlung von unnormalem zellwachstum
DE60019556D1 (de) 2-amino-benzoxazinonderivate zur behandlung von fettleibigkeit
DZ3327A1 (fr) Derives de benzimidazole nouveaux utiles comme agents antiproliferatifs.
DE60011570D1 (de) Arylpiperazinyl-cyclohexyl indolderivate zur behandlung von depressionen
DE60218493D1 (de) Substituierte 7-aza-ä2.2.1übicycloheptane für die behandlung von krankheiten
ATE438630T1 (de) 5-sulfanyl-4h-1,2,4-triazolderivate und deren verwendung zur behandlung von somatostatine vermittelten krankheiten
DE60043692D1 (de) Acyl derivate zur behandlung von krankheiten die in zusammenhang mit vla-4 stehen
DE60001421D1 (de) Behandlung von abgas
DE60019555D1 (de) 2-oxy-benzoxazinonderivate zur behandlung von fettleibigkeit
DE60016449D1 (de) Beschichtungsverfahren
EE04747B1 (et) Amiini-plaatina komplekside valmistamismeetod
DE60216275D1 (de) Verwendung von mit azetidinon substituierten derivaten bei der behandlung der alzheimer-krankheit
DE60325498D1 (de) 1-acyl-pyrrolidin-derivate für die behandlung von viralen infektionen
DE60030210D1 (de) Elektrolytisches Behandlungsverfahren
ATE500830T1 (de) Behandlung von krebs beim menschen mit et743
DE60239558D1 (de) Kombinationen für die behandlung von immun-entzündlichen erkrankungen
ATE384699T1 (de) 2,6-chinolinyl- und 2,6-naphthylderivate und deren verwendungen zur behandlung von vla-4 bezogenen krankheiten
ITBO940276A0 (it) Dispositivo di rullatura per elementi allungati, particolarmente per la produzione di articoli da fumo
DE69917684D1 (de) Betulinsäure-derivate mit antiangiogener wirkung, verfahren zur herstellung solcher derivate und deren verwendung für die behandlung tumorassoziierter angiogenese
DE60006990D1 (de) Pyrrolderivate mit antiproliferativer wirkung geeignet für die behandlung von krebs
DE60037780D1 (de) Variables induktives Element
DE60112423D1 (de) Verwendung von substituierten distamycin-acryloylderivaten zur behandlung von tumoren die mit erhöhten glutathion-spiegeln zusammenhängen
DE60021521D1 (de) Isonipecotamide zur behandlung von integrin vermittelten störungen
FR2792173B1 (fr) Procede de fabrication de vetements ou de parties de vetements par deformation

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee