HRP20010075A2 - Methods and compositions for treating gastro-esophageal reflux disease - Google Patents

Methods and compositions for treating gastro-esophageal reflux disease Download PDF

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Publication number
HRP20010075A2
HRP20010075A2 HR20010075A HRP20010075A HRP20010075A2 HR P20010075 A2 HRP20010075 A2 HR P20010075A2 HR 20010075 A HR20010075 A HR 20010075A HR P20010075 A HRP20010075 A HR P20010075A HR P20010075 A2 HRP20010075 A2 HR P20010075A2
Authority
HR
Croatia
Prior art keywords
norcisapride
pharmaceutically acceptable
administration
cisapride
acceptable salt
Prior art date
Application number
HR20010075A
Other languages
English (en)
Croatian (hr)
Inventor
John R Mccullough
Thomas P Jerussi
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of HRP20010075A2 publication Critical patent/HRP20010075A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20010075A 1998-07-28 2001-01-26 Methods and compositions for treating gastro-esophageal reflux disease HRP20010075A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/123,892 US6147093A (en) 1996-07-19 1998-07-28 Methods for treating gastroesophageal reflux disease
PCT/US1999/016736 WO2000006165A1 (en) 1998-07-28 1999-07-23 Methods and compositions for treating gastro-esophageal reflux disease

Publications (1)

Publication Number Publication Date
HRP20010075A2 true HRP20010075A2 (en) 2002-02-28

Family

ID=22411520

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010075A HRP20010075A2 (en) 1998-07-28 2001-01-26 Methods and compositions for treating gastro-esophageal reflux disease

Country Status (25)

Country Link
US (4) US6147093A (cs)
EP (1) EP1100502A1 (cs)
JP (1) JP2002521448A (cs)
KR (1) KR20010071047A (cs)
CN (1) CN1320036A (cs)
AR (1) AR019947A1 (cs)
AU (1) AU5126099A (cs)
BG (1) BG105218A (cs)
BR (1) BR9912581A (cs)
CA (1) CA2338465A1 (cs)
CO (1) CO5060499A1 (cs)
CZ (1) CZ295776B6 (cs)
EA (1) EA200100188A1 (cs)
EE (1) EE200100051A (cs)
HK (1) HK1041226A1 (cs)
HR (1) HRP20010075A2 (cs)
HU (1) HUP0102979A3 (cs)
ID (1) ID28894A (cs)
IL (1) IL141047A0 (cs)
NO (1) NO20010464L (cs)
NZ (1) NZ509671A (cs)
PL (1) PL345764A1 (cs)
SK (1) SK1202001A3 (cs)
TR (1) TR200100921T2 (cs)
WO (1) WO2000006165A1 (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147093A (en) * 1996-07-19 2000-11-14 Sepracor Inc. Methods for treating gastroesophageal reflux disease
BR9811676A (pt) * 1997-07-11 2000-09-19 Janssen Pharmaceutica Nv (+) norcisaprida útil para distúrbios mediados por 5-ht3 e 5-ht4
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
DE10314916A1 (de) 2003-04-01 2004-10-21 Endress + Hauser Flowtec Ag, Reinach Vorrichtung zur Bestimmung und/oder Überwachung des Volumen- und/oder Massenstroms eines Mediums
JP4740152B2 (ja) * 2003-12-23 2011-08-03 セロドス アクスイェ セルスカブ 末梢性5−ht受容体の修飾因子
US8524736B2 (en) 2004-01-07 2013-09-03 Armetheon, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
DK2194053T3 (da) 2004-01-07 2013-07-01 Armetheon Inc Methoxypiperidinderivater til brug i behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet.
US8138204B2 (en) * 2004-01-07 2012-03-20 Aryx Therapeutics, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US20050160544A1 (en) * 2004-01-26 2005-07-28 Marc Geller Contoured grill brush
CA2620379C (en) * 2005-08-31 2015-02-24 Aryx Therapeutics, Inc. Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
WO2007149929A1 (en) * 2006-06-23 2007-12-27 Aryx Therapeutics, Inc. Piperidine derivatives for the treatment of gastrointestinal and cns disorders
US10570127B1 (en) 2018-11-05 2020-02-25 Renexxion, Llc Material and methods for the treatment of gastro-intestinal disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
AU4770593A (en) * 1992-07-07 1994-01-31 Sepracor, Inc. Methods of using (+) cisapride for the treatment of gastro-esophageal reflux disease and other disorders
JPH08502032A (ja) * 1992-07-07 1996-03-05 セプラコア インコーポレーテッド 胃食道逆流疾患およびその他の障害を治療するために▲(−)▼シサプリドを使用する方法
AU7397194A (en) * 1993-07-06 1995-02-06 Mcneil-Ppc, Inc. H2 antagonist-gastrointestinal motility agent combinations
US5712293A (en) * 1995-06-07 1998-01-27 Sepracor, Inc. Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride
US5739151A (en) * 1996-07-19 1998-04-14 Sepracor Inc. Method for treating emesis and central nervous system disorders using optically pure (+) norcisapride
US6147093A (en) * 1996-07-19 2000-11-14 Sepracor Inc. Methods for treating gastroesophageal reflux disease
BR9811676A (pt) * 1997-07-11 2000-09-19 Janssen Pharmaceutica Nv (+) norcisaprida útil para distúrbios mediados por 5-ht3 e 5-ht4

Also Published As

Publication number Publication date
CA2338465A1 (en) 2000-02-10
SK1202001A3 (en) 2001-08-06
EP1100502A1 (en) 2001-05-23
NZ509671A (en) 2003-08-29
JP2002521448A (ja) 2002-07-16
CO5060499A1 (es) 2001-07-30
HUP0102979A3 (en) 2002-01-28
CN1320036A (zh) 2001-10-31
AR019947A1 (es) 2002-03-27
BR9912581A (pt) 2001-05-02
AU5126099A (en) 2000-02-21
CZ2001348A3 (cs) 2002-01-16
WO2000006165A1 (en) 2000-02-10
US6632827B2 (en) 2003-10-14
NO20010464D0 (no) 2001-01-26
CZ295776B6 (cs) 2005-11-16
IL141047A0 (en) 2002-02-10
US20010020031A1 (en) 2001-09-06
ID28894A (id) 2001-07-12
HUP0102979A2 (hu) 2001-12-28
EA200100188A1 (ru) 2001-08-27
US6147093A (en) 2000-11-14
US6242465B1 (en) 2001-06-05
NO20010464L (no) 2001-03-23
HK1041226A1 (zh) 2002-07-05
EE200100051A (et) 2002-06-17
TR200100921T2 (tr) 2001-10-22
US20040044039A1 (en) 2004-03-04
KR20010071047A (ko) 2001-07-28
PL345764A1 (en) 2002-01-02
BG105218A (en) 2001-11-30

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