HUP0102979A3 - Pharmaceutical compositions for treating gastro-esophageal reflux disease containing (+)-norcisapride as active ingredient - Google Patents
Pharmaceutical compositions for treating gastro-esophageal reflux disease containing (+)-norcisapride as active ingredientInfo
- Publication number
- HUP0102979A3 HUP0102979A3 HU0102979A HUP0102979A HUP0102979A3 HU P0102979 A3 HUP0102979 A3 HU P0102979A3 HU 0102979 A HU0102979 A HU 0102979A HU P0102979 A HUP0102979 A HU P0102979A HU P0102979 A3 HUP0102979 A3 HU P0102979A3
- Authority
- HU
- Hungary
- Prior art keywords
- norcisapride
- active ingredient
- pharmaceutical compositions
- reflux disease
- esophageal reflux
- Prior art date
Links
- ZDLILMQNLSEPLK-UHFFFAOYSA-N 2-chloro-5-methoxy-n-piperidin-4-ylpyrimidin-4-amine Chemical compound COC1=CN=C(Cl)N=C1NC1CCNCC1 ZDLILMQNLSEPLK-UHFFFAOYSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/123,892 US6147093A (en) | 1996-07-19 | 1998-07-28 | Methods for treating gastroesophageal reflux disease |
| PCT/US1999/016736 WO2000006165A1 (en) | 1998-07-28 | 1999-07-23 | Methods and compositions for treating gastro-esophageal reflux disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0102979A2 HUP0102979A2 (hu) | 2001-12-28 |
| HUP0102979A3 true HUP0102979A3 (en) | 2002-01-28 |
Family
ID=22411520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0102979A HUP0102979A3 (en) | 1998-07-28 | 1999-07-23 | Pharmaceutical compositions for treating gastro-esophageal reflux disease containing (+)-norcisapride as active ingredient |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US6147093A (hu) |
| EP (1) | EP1100502A1 (hu) |
| JP (1) | JP2002521448A (hu) |
| KR (1) | KR20010071047A (hu) |
| CN (1) | CN1320036A (hu) |
| AR (1) | AR019947A1 (hu) |
| AU (1) | AU5126099A (hu) |
| BG (1) | BG105218A (hu) |
| BR (1) | BR9912581A (hu) |
| CA (1) | CA2338465A1 (hu) |
| CO (1) | CO5060499A1 (hu) |
| CZ (1) | CZ295776B6 (hu) |
| EA (1) | EA200100188A1 (hu) |
| EE (1) | EE200100051A (hu) |
| HK (1) | HK1041226A1 (hu) |
| HR (1) | HRP20010075A2 (hu) |
| HU (1) | HUP0102979A3 (hu) |
| ID (1) | ID28894A (hu) |
| IL (1) | IL141047A0 (hu) |
| NO (1) | NO20010464L (hu) |
| NZ (1) | NZ509671A (hu) |
| PL (1) | PL345764A1 (hu) |
| SK (1) | SK1202001A3 (hu) |
| TR (1) | TR200100921T2 (hu) |
| WO (1) | WO2000006165A1 (hu) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6147093A (en) * | 1996-07-19 | 2000-11-14 | Sepracor Inc. | Methods for treating gastroesophageal reflux disease |
| BR9811676A (pt) * | 1997-07-11 | 2000-09-19 | Janssen Pharmaceutica Nv | (+) norcisaprida útil para distúrbios mediados por 5-ht3 e 5-ht4 |
| US6353005B1 (en) | 1999-03-02 | 2002-03-05 | Sepracor, Inc. | Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist |
| DE10314916A1 (de) | 2003-04-01 | 2004-10-21 | Endress + Hauser Flowtec Ag, Reinach | Vorrichtung zur Bestimmung und/oder Überwachung des Volumen- und/oder Massenstroms eines Mediums |
| JP4740152B2 (ja) * | 2003-12-23 | 2011-08-03 | セロドス アクスイェ セルスカブ | 末梢性５−ｈｔ受容体の修飾因子 |
| US8524736B2 (en) | 2004-01-07 | 2013-09-03 | Armetheon, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| DK2194053T3 (da) | 2004-01-07 | 2013-07-01 | Armetheon Inc | Methoxypiperidinderivater til brug i behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet. |
| US8138204B2 (en) * | 2004-01-07 | 2012-03-20 | Aryx Therapeutics, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| US20050160544A1 (en) * | 2004-01-26 | 2005-07-28 | Marc Geller | Contoured grill brush |
| CA2620379C (en) * | 2005-08-31 | 2015-02-24 | Aryx Therapeutics, Inc. | Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders |
| WO2007149929A1 (en) * | 2006-06-23 | 2007-12-27 | Aryx Therapeutics, Inc. | Piperidine derivatives for the treatment of gastrointestinal and cns disorders |
| US10570127B1 (en) | 2018-11-05 | 2020-02-25 | Renexxion, Llc | Material and methods for the treatment of gastro-intestinal disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5057525A (en) * | 1981-10-01 | 1991-10-15 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives |
| US4962115A (en) * | 1981-10-01 | 1990-10-09 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| US5137896A (en) * | 1981-10-01 | 1992-08-11 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| AU4770593A (en) * | 1992-07-07 | 1994-01-31 | Sepracor, Inc. | Methods of using (+) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
| JPH08502032A (ja) * | 1992-07-07 | 1996-03-05 | セプラコア インコーポレーテッド | 胃食道逆流疾患およびその他の障害を治療するために▲（−）▼シサプリドを使用する方法 |
| AU7397194A (en) * | 1993-07-06 | 1995-02-06 | Mcneil-Ppc, Inc. | H2 antagonist-gastrointestinal motility agent combinations |
| US5712293A (en) * | 1995-06-07 | 1998-01-27 | Sepracor, Inc. | Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride |
| US5739151A (en) * | 1996-07-19 | 1998-04-14 | Sepracor Inc. | Method for treating emesis and central nervous system disorders using optically pure (+) norcisapride |
| US6147093A (en) * | 1996-07-19 | 2000-11-14 | Sepracor Inc. | Methods for treating gastroesophageal reflux disease |
| BR9811676A (pt) * | 1997-07-11 | 2000-09-19 | Janssen Pharmaceutica Nv | (+) norcisaprida útil para distúrbios mediados por 5-ht3 e 5-ht4 |
-
1998
- 1998-07-28 US US09/123,892 patent/US6147093A/en not_active Expired - Fee Related
-
1999
- 1999-07-23 EE EEP200100051A patent/EE200100051A/xx unknown
- 1999-07-23 CA CA002338465A patent/CA2338465A1/en not_active Abandoned
- 1999-07-23 CN CN99811374A patent/CN1320036A/zh active Pending
- 1999-07-23 AU AU51260/99A patent/AU5126099A/en not_active Abandoned
- 1999-07-23 SK SK120-2001A patent/SK1202001A3/sk unknown
- 1999-07-23 EA EA200100188A patent/EA200100188A1/ru unknown
- 1999-07-23 JP JP2000562019A patent/JP2002521448A/ja active Pending
- 1999-07-23 KR KR1020017001188A patent/KR20010071047A/ko not_active Application Discontinuation
- 1999-07-23 EP EP99935877A patent/EP1100502A1/en not_active Withdrawn
- 1999-07-23 ID IDW20010484A patent/ID28894A/id unknown
- 1999-07-23 WO PCT/US1999/016736 patent/WO2000006165A1/en active IP Right Grant
- 1999-07-23 HU HU0102979A patent/HUP0102979A3/hu unknown
- 1999-07-23 IL IL14104799A patent/IL141047A0/xx unknown
- 1999-07-23 TR TR2001/00921T patent/TR200100921T2/xx unknown
- 1999-07-23 PL PL99345764A patent/PL345764A1/xx not_active Application Discontinuation
- 1999-07-23 BR BR9912581-1A patent/BR9912581A/pt not_active Application Discontinuation
- 1999-07-23 CZ CZ2001348A patent/CZ295776B6/cs not_active IP Right Cessation
- 1999-07-23 NZ NZ509671A patent/NZ509671A/en unknown
- 1999-07-28 CO CO99047624A patent/CO5060499A1/es unknown
- 1999-07-28 AR ARP990103729A patent/AR019947A1/es not_active Application Discontinuation
-
2000
- 2000-05-18 US US09/573,423 patent/US6242465B1/en not_active Expired - Fee Related
-
2001
- 2001-01-26 HR HR20010075A patent/HRP20010075A2/hr not_active Application Discontinuation
- 2001-01-26 NO NO20010464A patent/NO20010464L/no not_active Application Discontinuation
- 2001-02-05 BG BG105218A patent/BG105218A/xx unknown
- 2001-03-16 US US09/809,165 patent/US6632827B2/en not_active Expired - Fee Related
-
2002
- 2002-04-24 HK HK02103109.0A patent/HK1041226A1/zh unknown
-
2003
- 2003-09-03 US US10/653,072 patent/US20040044039A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2338465A1 (en) | 2000-02-10 |
| SK1202001A3 (en) | 2001-08-06 |
| EP1100502A1 (en) | 2001-05-23 |
| NZ509671A (en) | 2003-08-29 |
| JP2002521448A (ja) | 2002-07-16 |
| CO5060499A1 (es) | 2001-07-30 |
| CN1320036A (zh) | 2001-10-31 |
| AR019947A1 (es) | 2002-03-27 |
| HRP20010075A2 (en) | 2002-02-28 |
| BR9912581A (pt) | 2001-05-02 |
| AU5126099A (en) | 2000-02-21 |
| CZ2001348A3 (cs) | 2002-01-16 |
| WO2000006165A1 (en) | 2000-02-10 |
| US6632827B2 (en) | 2003-10-14 |
| NO20010464D0 (no) | 2001-01-26 |
| CZ295776B6 (cs) | 2005-11-16 |
| IL141047A0 (en) | 2002-02-10 |
| US20010020031A1 (en) | 2001-09-06 |
| ID28894A (id) | 2001-07-12 |
| HUP0102979A2 (hu) | 2001-12-28 |
| EA200100188A1 (ru) | 2001-08-27 |
| US6147093A (en) | 2000-11-14 |
| US6242465B1 (en) | 2001-06-05 |
| NO20010464L (no) | 2001-03-23 |
| HK1041226A1 (zh) | 2002-07-05 |
| EE200100051A (et) | 2002-06-17 |
| TR200100921T2 (tr) | 2001-10-22 |
| US20040044039A1 (en) | 2004-03-04 |
| KR20010071047A (ko) | 2001-07-28 |
| PL345764A1 (en) | 2002-01-02 |
| BG105218A (en) | 2001-11-30 |
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