HRP20000066A2 - 2-acylaminopropanamines as tachykinin receptor antagonists - Google Patents
2-acylaminopropanamines as tachykinin receptor antagonists Download PDFInfo
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- HRP20000066A2 HRP20000066A2 HR20000066A HRP20000066A HRP20000066A2 HR P20000066 A2 HRP20000066 A2 HR P20000066A2 HR 20000066 A HR20000066 A HR 20000066A HR P20000066 A HRP20000066 A HR P20000066A HR P20000066 A2 HRP20000066 A2 HR P20000066A2
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- Prior art keywords
- alkyl
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- alkoxy
- refers
- hydroxyl
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Classifications
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5510597P | 1997-08-06 | 1997-08-06 | |
| PCT/US1998/016313 WO1999007681A1 (en) | 1997-08-06 | 1998-08-06 | 2-acylaminopropanamines as tachykinin receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20000066A2 true HRP20000066A2 (en) | 2000-10-31 |
Family
ID=21995634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20000066A HRP20000066A2 (en) | 1997-08-06 | 2000-02-04 | 2-acylaminopropanamines as tachykinin receptor antagonists |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6339094B1 (ko) |
| EP (1) | EP1003723A4 (ko) |
| JP (1) | JP2001512717A (ko) |
| KR (1) | KR20010022580A (ko) |
| CN (1) | CN1265652A (ko) |
| AU (1) | AU8692698A (ko) |
| BR (1) | BR9811819A (ko) |
| CA (1) | CA2298702A1 (ko) |
| EA (1) | EA200000197A1 (ko) |
| HR (1) | HRP20000066A2 (ko) |
| HU (1) | HUP0003548A3 (ko) |
| ID (1) | ID24309A (ko) |
| IL (1) | IL134155A0 (ko) |
| NO (1) | NO20000518L (ko) |
| PL (1) | PL338456A1 (ko) |
| TR (1) | TR200000287T2 (ko) |
| WO (1) | WO1999007681A1 (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002250876B2 (en) * | 2001-04-23 | 2005-03-03 | F. Hoffmann-La Roche Ag | Use of NK-1 receptor antagonists against benign prostatic hyperplasia |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| US20080190324A1 (en) * | 2007-02-02 | 2008-08-14 | Chianelli Russell R | Organic/inorganic complexes as color compositions |
| NO2729147T3 (ko) | 2011-07-04 | 2018-02-03 | ||
| WO2019162519A1 (en) | 2018-02-26 | 2019-08-29 | Ospedale San Raffaele S.R.L. | Nk-1 antagonists for use in the treatment of ocular pain |
| EP4117673A1 (en) | 2020-03-11 | 2023-01-18 | Ospedale San Raffaele S.r.l. | Treatment of stem cell deficiency |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340588C (en) | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| US5278316A (en) | 1989-06-29 | 1994-01-11 | Warner-Lambert Company | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives |
| DK0533280T4 (da) * | 1991-09-20 | 2005-02-28 | Glaxo Group Ltd | Ny medicinsk anvendelse af tachykininantagonister |
| US5328927A (en) | 1992-03-03 | 1994-07-12 | Merck Sharpe & Dohme, Ltd. | Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
| US5380872A (en) * | 1992-07-14 | 1995-01-10 | Glaxo Inc. | Modulators of cholecystokinin |
| EP0655055B1 (en) | 1992-08-13 | 2000-11-29 | Warner-Lambert Company | Tachykinin antagonists |
| AU5342894A (en) * | 1992-10-30 | 1994-05-24 | Merck Sharp & Dohme Limited | Tachykinin antagonists |
| US6403577B1 (en) * | 1993-11-17 | 2002-06-11 | Eli Lilly And Company | Hexamethyleneiminyl tachykinin receptor antagonists |
| US5491140A (en) * | 1994-06-30 | 1996-02-13 | Eli Lilly And Company | Naphthyl tachykinin receptor antagonists to treat physiological conditions |
| CN1067067C (zh) | 1994-07-12 | 2001-06-13 | 伊莱利利公司 | 杂环速激肽受体拮抗物 |
| EP1005454A4 (en) * | 1997-08-06 | 2003-01-15 | Lilly Co Eli | 2-ACYLAMINOPROPANAMINE FOR USE AS TACHYKININ RECEPTOR ANTAGONISTS |
-
1998
- 1998-08-06 CA CA002298702A patent/CA2298702A1/en not_active Abandoned
- 1998-08-06 KR KR1020007001171A patent/KR20010022580A/ko not_active Application Discontinuation
- 1998-08-06 US US09/463,640 patent/US6339094B1/en not_active Expired - Fee Related
- 1998-08-06 ID IDW20000219A patent/ID24309A/id unknown
- 1998-08-06 TR TR2000/00287T patent/TR200000287T2/xx unknown
- 1998-08-06 EP EP98938395A patent/EP1003723A4/en not_active Withdrawn
- 1998-08-06 JP JP2000506185A patent/JP2001512717A/ja not_active Withdrawn
- 1998-08-06 BR BR9811819-6A patent/BR9811819A/pt not_active Application Discontinuation
- 1998-08-06 PL PL98338456A patent/PL338456A1/xx unknown
- 1998-08-06 EA EA200000197A patent/EA200000197A1/ru unknown
- 1998-08-06 CN CN98807880A patent/CN1265652A/zh active Pending
- 1998-08-06 AU AU86926/98A patent/AU8692698A/en not_active Abandoned
- 1998-08-06 IL IL13415598A patent/IL134155A0/xx unknown
- 1998-08-06 WO PCT/US1998/016313 patent/WO1999007681A1/en not_active Application Discontinuation
- 1998-08-06 HU HU0003548A patent/HUP0003548A3/hu unknown
-
2000
- 2000-02-01 NO NO20000518A patent/NO20000518L/no not_active Application Discontinuation
- 2000-02-04 HR HR20000066A patent/HRP20000066A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL134155A0 (en) | 2001-04-30 |
| NO20000518L (no) | 2000-03-31 |
| EA200000197A1 (ru) | 2000-10-30 |
| US6339094B1 (en) | 2002-01-15 |
| EP1003723A1 (en) | 2000-05-31 |
| EP1003723A4 (en) | 2000-11-02 |
| KR20010022580A (ko) | 2001-03-26 |
| PL338456A1 (en) | 2000-11-06 |
| WO1999007681A1 (en) | 1999-02-18 |
| CN1265652A (zh) | 2000-09-06 |
| NO20000518D0 (no) | 2000-02-01 |
| JP2001512717A (ja) | 2001-08-28 |
| ID24309A (id) | 2000-07-13 |
| AU8692698A (en) | 1999-03-01 |
| BR9811819A (pt) | 2000-08-15 |
| CA2298702A1 (en) | 1999-02-18 |
| HUP0003548A3 (en) | 2002-04-29 |
| TR200000287T2 (tr) | 2000-07-21 |
| HUP0003548A2 (hu) | 2002-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| OBST | Application withdrawn |