HK99287A - Process for the preparation of chiral hydantoins,and a novel hydantoin produced by said process and a pharmaceutical composition containing it - Google Patents
Process for the preparation of chiral hydantoins,and a novel hydantoin produced by said process and a pharmaceutical composition containing itInfo
- Publication number
- HK99287A HK99287A HK992/87A HK99287A HK99287A HK 99287 A HK99287 A HK 99287A HK 992/87 A HK992/87 A HK 992/87A HK 99287 A HK99287 A HK 99287A HK 99287 A HK99287 A HK 99287A
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- pharmaceutical composition
- composition containing
- novel hydantoin
- hydantoins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/135,137 US4286098A (en) | 1980-03-28 | 1980-03-28 | Process for the preparation of chiral hydantoins |
Publications (1)
Publication Number | Publication Date |
---|---|
HK99287A true HK99287A (en) | 1987-12-31 |
Family
ID=22466719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK992/87A HK99287A (en) | 1980-03-28 | 1987-12-24 | Process for the preparation of chiral hydantoins,and a novel hydantoin produced by said process and a pharmaceutical composition containing it |
Country Status (12)
Country | Link |
---|---|
US (1) | US4286098A (ja) |
EP (2) | EP0037672B1 (ja) |
JP (2) | JPS56152483A (ja) |
AR (1) | AR225498A1 (ja) |
DE (1) | DE3174610D1 (ja) |
DK (1) | DK139881A (ja) |
ES (1) | ES500744A0 (ja) |
GR (1) | GR74481B (ja) |
HK (1) | HK99287A (ja) |
IE (1) | IE52337B1 (ja) |
MY (1) | MY8800093A (ja) |
SG (1) | SG69987G (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58124788A (ja) * | 1982-01-20 | 1983-07-25 | Eisai Co Ltd | 光学活性ヒダントイン誘導体,その製造方法ならびにそれを含有する治療用薬剤 |
US4528387A (en) * | 1982-11-10 | 1985-07-09 | Pfizer Inc. | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
US4435578A (en) * | 1982-11-10 | 1984-03-06 | Pfizer Inc. | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
US4431828A (en) * | 1982-11-10 | 1984-02-14 | Pfizer Inc. | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil |
US4620019A (en) * | 1984-08-23 | 1986-10-28 | Pfizer Inc. | S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil |
JPS6172762A (ja) * | 1984-09-17 | 1986-04-14 | Kanegafuchi Chem Ind Co Ltd | 光学活性ヒダントイン類の製造法 |
US4551542A (en) * | 1984-09-26 | 1985-11-05 | Pfizer Inc. | Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid |
US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
US5340829A (en) * | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
HU206618B (en) * | 1986-01-17 | 1992-12-28 | Pfizer | Process for producing hydroxyacetic acid derivatives for treating complications of diabetes and pharmaceutical compositions containing them |
JPH05508386A (ja) * | 1989-02-10 | 1993-11-25 | ワシントン リサーチ ファンデション | 免疫調整剤 |
US5151544A (en) * | 1990-05-25 | 1992-09-29 | Alcon Laboratories, Inc. | Intermediates in the preparation of chiral spirofluorenehydantoins |
US20040002615A1 (en) * | 2002-06-28 | 2004-01-01 | Allen David Robert | Preparation of chiral amino-nitriles |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
US4093799A (en) * | 1977-07-01 | 1978-06-06 | Morton-Norwich Products, Inc. | N-arylidene-4-chromanamines |
-
1980
- 1980-03-28 US US06/135,137 patent/US4286098A/en not_active Expired - Lifetime
-
1981
- 1981-03-23 GR GR64481A patent/GR74481B/el unknown
- 1981-03-23 AR AR284708A patent/AR225498A1/es active
- 1981-03-24 EP EP81301247A patent/EP0037672B1/en not_active Expired
- 1981-03-24 DE DE8181301247T patent/DE3174610D1/de not_active Expired
- 1981-03-24 EP EP84112748A patent/EP0145895B1/en not_active Expired
- 1981-03-26 ES ES500744A patent/ES500744A0/es active Granted
- 1981-03-27 IE IE709/81A patent/IE52337B1/en unknown
- 1981-03-27 DK DK139881A patent/DK139881A/da not_active Application Discontinuation
- 1981-03-27 JP JP4537181A patent/JPS56152483A/ja active Granted
-
1987
- 1987-08-27 SG SG699/87A patent/SG69987G/en unknown
- 1987-12-24 HK HK992/87A patent/HK99287A/xx unknown
-
1988
- 1988-01-08 JP JP63002381A patent/JPS63253086A/ja active Pending
- 1988-12-30 MY MY93/88A patent/MY8800093A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPS56152483A (en) | 1981-11-26 |
EP0145895A1 (en) | 1985-06-26 |
EP0037672A2 (en) | 1981-10-14 |
DK139881A (da) | 1981-09-29 |
US4286098A (en) | 1981-08-25 |
EP0145895B1 (en) | 1987-03-04 |
EP0037672A3 (en) | 1983-08-24 |
AR225498A1 (es) | 1982-03-31 |
IE52337B1 (en) | 1987-09-16 |
SG69987G (en) | 1988-02-19 |
JPS63253086A (ja) | 1988-10-20 |
ES8204737A1 (es) | 1982-01-16 |
MY8800093A (en) | 1988-12-31 |
IE810709L (en) | 1981-09-28 |
DE3174610D1 (en) | 1986-06-19 |
EP0037672B1 (en) | 1986-05-14 |
GR74481B (ja) | 1984-06-28 |
ES500744A0 (es) | 1982-01-16 |
JPS6340433B2 (ja) | 1988-08-11 |
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