HK98789A - Improvements in and relating to pyrimido(4,5-g)quinolines and intermediates - Google Patents

Improvements in and relating to pyrimido(4,5-g)quinolines and intermediates

Info

Publication number
HK98789A
HK98789A HK987/89A HK98789A HK98789A HK 98789 A HK98789 A HK 98789A HK 987/89 A HK987/89 A HK 987/89A HK 98789 A HK98789 A HK 98789A HK 98789 A HK98789 A HK 98789A
Authority
HK
Hong Kong
Prior art keywords
pyrimido
quinolines
intermediates
relating
Prior art date
Application number
HK987/89A
Other languages
English (en)
Inventor
Cynthia Lynn Nichols
Edmund Carl Kornfeld
Mark Mortensen Foreman
John Mehnert Schaus
Diane Lynn Huser
Richard Nolan Booher
David Taiwai Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/535,474 external-priority patent/US4521421A/en
Priority claimed from US06/535,503 external-priority patent/US4501890A/en
Priority claimed from US06/575,126 external-priority patent/US4528290A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK98789A publication Critical patent/HK98789A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK987/89A 1983-09-26 1989-12-14 Improvements in and relating to pyrimido(4,5-g)quinolines and intermediates HK98789A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US53551983A 1983-09-26 1983-09-26
US06/535,474 US4521421A (en) 1983-09-26 1983-09-26 Treatment of sexual dysfunction
US06/535,503 US4501890A (en) 1983-09-26 1983-09-26 Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines
US06/575,126 US4528290A (en) 1984-01-30 1984-01-30 Stimulating dopamine D-1 receptors
US60609184A 1984-05-02 1984-05-02

Publications (1)

Publication Number Publication Date
HK98789A true HK98789A (en) 1989-12-22

Family

ID=27541855

Family Applications (1)

Application Number Title Priority Date Filing Date
HK987/89A HK98789A (en) 1983-09-26 1989-12-14 Improvements in and relating to pyrimido(4,5-g)quinolines and intermediates

Country Status (16)

Country Link
EP (1) EP0139393B1 (pt)
JP (1) JPH01151581A (pt)
AU (2) AU569539B2 (pt)
CY (1) CY1495A (pt)
DE (1) DE3484583D1 (pt)
DK (4) DK164867C (pt)
FI (1) FI78091C (pt)
GB (1) GB2146985B (pt)
GR (1) GR80201B (pt)
HK (1) HK98789A (pt)
IE (1) IE57848B1 (pt)
IL (1) IL72730A (pt)
NZ (1) NZ209295A (pt)
PT (1) PT79112B (pt)
RO (1) RO89126A (pt)
SG (1) SG46389G (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212947A (en) * 1984-08-03 1988-07-28 Lilly Co Eli Preparation of tricyclic quinoline derivatives
US4764609A (en) * 1986-03-31 1988-08-16 Eli Lilly And Company Synthesis of 2-aminopyrimido[4,5-g]quinolines
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
US4762843A (en) * 1986-09-15 1988-08-09 Warner-Lambert Company Hetero [f] fused carbocyclic pyridines as dopaminergic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
JPS59202892A (ja) * 1983-05-04 1984-11-16 Ricoh Co Ltd 光学的情報記録媒体
US4507478A (en) * 1983-09-26 1985-03-26 Eli Lilly And Company 2-Mercaptopyrimidohexahydroquinolines and related compounds
NZ212947A (en) * 1984-08-03 1988-07-28 Lilly Co Eli Preparation of tricyclic quinoline derivatives

Also Published As

Publication number Publication date
NZ209295A (en) 1987-05-29
AU569539B2 (en) 1988-02-04
AU8216887A (en) 1988-03-31
EP0139393A2 (en) 1985-05-02
DK164867C (da) 1993-11-08
IE57848B1 (en) 1993-04-21
FI843282A (fi) 1985-03-27
DE3484583D1 (de) 1991-06-20
GB2146985A (en) 1985-05-01
GB8421160D0 (en) 1984-09-26
RO89126A (ro) 1986-04-30
DK400984D0 (da) 1984-08-22
JPH0529398B2 (pt) 1993-04-30
DK296190A (da) 1990-12-13
DK296290A (da) 1990-12-13
DK400984A (da) 1985-03-27
IE842154L (en) 1985-03-26
AU585473B2 (en) 1989-06-15
AU3228084A (en) 1985-04-04
PT79112B (en) 1986-11-14
SG46389G (en) 1989-12-22
DK169622B1 (da) 1994-12-27
DK169970B1 (da) 1995-04-18
DK164867B (da) 1992-08-31
DK296390A (da) 1990-12-13
FI843282A0 (fi) 1984-08-20
PT79112A (en) 1984-09-01
JPH01151581A (ja) 1989-06-14
GB2146985B (en) 1987-05-28
DK169948B1 (da) 1995-04-10
DK296190D0 (da) 1990-12-13
DK296390D0 (da) 1990-12-13
IL72730A (en) 1987-10-30
FI78091C (fi) 1989-06-12
IL72730A0 (en) 1984-11-30
CY1495A (en) 1990-02-16
EP0139393B1 (en) 1991-05-15
GR80201B (en) 1985-01-02
DK296290D0 (da) 1990-12-13
FI78091B (fi) 1989-02-28
EP0139393A3 (en) 1988-01-13

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)