GR80201B - Improvements in and relating to pyrimido (4,5-9) quinolines and intermediates - Google Patents

Improvements in and relating to pyrimido (4,5-9) quinolines and intermediates

Info

Publication number
GR80201B
GR80201B GR80201A GR840180201A GR80201B GR 80201 B GR80201 B GR 80201B GR 80201 A GR80201 A GR 80201A GR 840180201 A GR840180201 A GR 840180201A GR 80201 B GR80201 B GR 80201B
Authority
GR
Greece
Prior art keywords
pyrimido
quinolines
intermediates
relating
Prior art date
Application number
GR80201A
Other languages
English (en)
Inventor
Nichols Lynn Cynthia
Kornfeld Carl Edmund
Foreman Mortensen Mark
Schaus Mehnert John
Huser Lynn Diane
Booher Nolan Richard
Taiwai David Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/535,503 external-priority patent/US4501890A/en
Priority claimed from US06/535,474 external-priority patent/US4521421A/en
Priority claimed from US06/575,126 external-priority patent/US4528290A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR80201B publication Critical patent/GR80201B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GR80201A 1983-09-26 1984-08-23 Improvements in and relating to pyrimido (4,5-9) quinolines and intermediates GR80201B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US53551983A 1983-09-26 1983-09-26
US06/535,503 US4501890A (en) 1983-09-26 1983-09-26 Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines
US06/535,474 US4521421A (en) 1983-09-26 1983-09-26 Treatment of sexual dysfunction
US06/575,126 US4528290A (en) 1984-01-30 1984-01-30 Stimulating dopamine D-1 receptors
US60609184A 1984-05-02 1984-05-02

Publications (1)

Publication Number Publication Date
GR80201B true GR80201B (en) 1985-01-02

Family

ID=27541855

Family Applications (1)

Application Number Title Priority Date Filing Date
GR80201A GR80201B (en) 1983-09-26 1984-08-23 Improvements in and relating to pyrimido (4,5-9) quinolines and intermediates

Country Status (16)

Country Link
EP (1) EP0139393B1 (el)
JP (1) JPH01151581A (el)
AU (2) AU569539B2 (el)
CY (1) CY1495A (el)
DE (1) DE3484583D1 (el)
DK (4) DK164867C (el)
FI (1) FI78091C (el)
GB (1) GB2146985B (el)
GR (1) GR80201B (el)
HK (1) HK98789A (el)
IE (1) IE57848B1 (el)
IL (1) IL72730A (el)
NZ (1) NZ209295A (el)
PT (1) PT79112B (el)
RO (1) RO89126A (el)
SG (1) SG46389G (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR870000623B1 (ko) * 1984-08-03 1987-03-26 일라이 릴리 앤드 캄파니 트리사이클릭 퀴놀린 유도체의 제조방법
US4764609A (en) * 1986-03-31 1988-08-16 Eli Lilly And Company Synthesis of 2-aminopyrimido[4,5-g]quinolines
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
US4762843A (en) * 1986-09-15 1988-08-09 Warner-Lambert Company Hetero [f] fused carbocyclic pyridines as dopaminergic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
JPS59202892A (ja) * 1983-05-04 1984-11-16 Ricoh Co Ltd 光学的情報記録媒体
US4507478A (en) * 1983-09-26 1985-03-26 Eli Lilly And Company 2-Mercaptopyrimidohexahydroquinolines and related compounds
KR870000623B1 (ko) * 1984-08-03 1987-03-26 일라이 릴리 앤드 캄파니 트리사이클릭 퀴놀린 유도체의 제조방법

Also Published As

Publication number Publication date
DK296190A (da) 1990-12-13
DK296390D0 (da) 1990-12-13
HK98789A (en) 1989-12-22
CY1495A (en) 1990-02-16
DE3484583D1 (de) 1991-06-20
DK296190D0 (da) 1990-12-13
DK296290D0 (da) 1990-12-13
PT79112A (en) 1984-09-01
DK169948B1 (da) 1995-04-10
GB8421160D0 (en) 1984-09-26
AU3228084A (en) 1985-04-04
EP0139393A2 (en) 1985-05-02
DK169970B1 (da) 1995-04-18
IE57848B1 (en) 1993-04-21
IL72730A0 (en) 1984-11-30
JPH01151581A (ja) 1989-06-14
IL72730A (en) 1987-10-30
FI78091B (fi) 1989-02-28
DK164867B (da) 1992-08-31
EP0139393A3 (en) 1988-01-13
GB2146985A (en) 1985-05-01
AU585473B2 (en) 1989-06-15
DK169622B1 (da) 1994-12-27
EP0139393B1 (en) 1991-05-15
JPH0529398B2 (el) 1993-04-30
NZ209295A (en) 1987-05-29
IE842154L (en) 1985-03-26
RO89126A (ro) 1986-04-30
PT79112B (en) 1986-11-14
SG46389G (en) 1989-12-22
DK400984A (da) 1985-03-27
DK296290A (da) 1990-12-13
DK400984D0 (da) 1984-08-22
GB2146985B (en) 1987-05-28
DK164867C (da) 1993-11-08
AU569539B2 (en) 1988-02-04
FI843282A0 (fi) 1984-08-20
DK296390A (da) 1990-12-13
FI843282A (fi) 1985-03-27
AU8216887A (en) 1988-03-31
FI78091C (fi) 1989-06-12

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