HK86090A - N-phenylmethylalkadienamide derivatives and compositions for use as analgesics - Google Patents

N-phenylmethylalkadienamide derivatives and compositions for use as analgesics Download PDF

Info

Publication number
HK86090A
HK86090A HK860/90A HK86090A HK86090A HK 86090 A HK86090 A HK 86090A HK 860/90 A HK860/90 A HK 860/90A HK 86090 A HK86090 A HK 86090A HK 86090 A HK86090 A HK 86090A
Authority
HK
Hong Kong
Prior art keywords
pharmaceutically
alkadienamides
compositions
acceptable salts
phenylmethylalkadienamide
Prior art date
Application number
HK860/90A
Other languages
English (en)
Inventor
Robert Lahann Thomas
Michael Janusz John
Lee Buckwalter Brian
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Publication of HK86090A publication Critical patent/HK86090A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK860/90A 1983-07-14 1990-10-18 N-phenylmethylalkadienamide derivatives and compositions for use as analgesics HK86090A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/514,207 US4544669A (en) 1983-07-14 1983-07-14 Compounds and compositions useful for producing analgesia

Publications (1)

Publication Number Publication Date
HK86090A true HK86090A (en) 1990-10-25

Family

ID=24046232

Family Applications (1)

Application Number Title Priority Date Filing Date
HK860/90A HK86090A (en) 1983-07-14 1990-10-18 N-phenylmethylalkadienamide derivatives and compositions for use as analgesics

Country Status (15)

Country Link
US (1) US4544669A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0132346B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS6075454A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU561216B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1244047A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3460819D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK164851C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2144414B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK86090A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE57566B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY102023A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ208898A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH21840A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG44390G (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA845266B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493848A (en) * 1983-07-14 1985-01-15 The Procter & Gamble Company Compositions and methods useful for producing analgesia
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
EP0187009B1 (en) * 1984-12-20 1988-07-06 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
US4885027A (en) * 1985-04-05 1989-12-05 Chevron Research Company Herbicidal arylmethylenesulfonamido-acetamide and thioacetamide derivatives
GB2178031B (en) 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4990533A (en) * 1985-12-20 1991-02-05 Warner-Lambert Co. Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4980366A (en) * 1986-08-19 1990-12-25 Warner-Lambert Co. Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US6239180B1 (en) 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
WO1998051290A2 (en) 1997-05-16 1998-11-19 Children's Medical Center Corporation Local anesthetic formulations comprising a site 1 sodium channel blocker combined with a second active agent
US6689399B1 (en) 2000-03-16 2004-02-10 James R. Dickson Transdermal delivery of an anti-inflammatory composition
AU2002254007B2 (en) 2001-02-22 2006-09-21 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
EP1610742B1 (en) 2003-04-10 2015-01-21 Neurogesx, Inc. Uses and compositions for administration of capsaicin
WO2006060505A2 (en) * 2004-12-01 2006-06-08 Dacanay Rhodel G Capsaicin nutritional supplement
ZA200707492B (en) * 2005-02-14 2009-02-25 Neurogesx Inc Device for delivery of TRPV1 agonists
CA2602832A1 (en) * 2005-03-30 2006-10-05 Keith R. Bley Low-concentration capsaicin patch and methods for treating neuropathic pain
US7632519B2 (en) * 2005-04-25 2009-12-15 Neurogesx, Inc. TRPV1 agonist compounds, formulations, prodrugs, methods for using the same
US8952152B2 (en) 2009-03-24 2015-02-10 Proteus S.A. Methods for purifying phycotoxins, pharmaceutical compositions containing purified phycotoxins, and methods of use thereof
PL2629610T3 (pl) 2010-07-27 2018-02-28 Flex Pharma, Inc. Sposoby i kompozycje do zapobiegania i zmniejszania kurczy mięśni i do regeneracji po nerwowo-mięśniowym podrażnieniu i zmęczeniu po ćwiczeniach fizycznych
EP2646107A2 (en) 2010-12-01 2013-10-09 Spinal Modulation Inc. Agent delivery systems for selective neuromodulation
KR20210062693A (ko) 2013-03-15 2021-05-31 더 칠드런스 메디칼 센터 코포레이션 지속성 국소 마취용 네오삭시톡신 조합 제형
CN103739511A (zh) * 2013-12-20 2014-04-23 白城艾高食品有限公司 一种萃取辣椒碱的方法
CN105439889B (zh) * 2015-11-20 2017-08-22 安徽省逸欣铭医药科技有限公司 一种香兰素胺类新化合物、其制备方法及医药用途
US11253493B2 (en) 2017-01-23 2022-02-22 Cliff-Cartwright Corporation Compositions and methods affecting exercise performance

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE938014C (de) * 1952-11-05 1956-01-19 Beiersdorf & Co A G P Verfahren zur Herstellung kristallisierter Vanillylamide
DE1166766B (de) * 1961-08-04 1964-04-02 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen Phenylalkylcarbonsaeureamiden
US3621043A (en) * 1963-02-06 1971-11-16 Sumitomo Chemical Co N-substituted octadecadienoic acid amides as cholesterol lowering agents
JPS4218610B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-08-28 1967-09-23
GB1051286A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-04-28
SE353319B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-08-15 1973-01-29 Sumitomo Chemical Co
US3558500A (en) * 1968-02-07 1971-01-26 Buckman Labor Inc Method for the control of scale using n,n-dimethylamides of 18 carbon unsaturated carboxylic acids
US3920523A (en) * 1971-03-17 1975-11-18 Akzona Inc Thin film evaporation of a crude amide feed in mixture with an alkali metal hydroxide
US3888893A (en) * 1971-06-14 1975-06-10 John B Siddall Unsaturated amides
US3816484A (en) * 1971-10-08 1974-06-11 Zoecon Corp Aliphatic hydrocarbon 2,4-dienamides
US3803185A (en) * 1971-11-22 1974-04-09 Zoecon Corp Novel 2,4-dienamides
JPS5619344B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-11-11 1981-05-07
DE2752366A1 (de) * 1977-11-24 1979-05-31 Bayer Ag 3,3-dimethyl-4-penten-thiosaeureamide und verfahren zu ihrer herstellung
US4238508A (en) * 1979-08-17 1980-12-09 The Research Foundation Of State University Of New York Method for analgesia using 3-hydroxyacetanilide
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
US4401663A (en) * 1981-06-30 1983-08-30 The Procter & Gamble Company Novel sulfonamide derivatives

Also Published As

Publication number Publication date
MY102023A (en) 1992-02-29
CA1244047A (en) 1988-11-01
EP0132346B1 (en) 1986-09-24
JPS6075454A (ja) 1985-04-27
IE841813L (en) 1985-01-14
EP0132346A1 (en) 1985-01-30
AU561216B2 (en) 1987-04-30
SG44390G (en) 1990-12-21
PH21840A (en) 1988-03-17
GB2144414A (en) 1985-03-06
JPH0510334B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-02-09
US4544669A (en) 1985-10-01
ZA845266B (en) 1985-03-27
DK345784D0 (da) 1984-07-13
DK164851B (da) 1992-08-31
IE57566B1 (en) 1992-12-16
DE3460819D1 (en) 1986-10-30
GB8417624D0 (en) 1984-08-15
AU3058584A (en) 1985-01-17
DK345784A (da) 1985-01-15
DK164851C (da) 1993-01-18
NZ208898A (en) 1988-03-30
GB2144414B (en) 1987-11-11

Similar Documents

Publication Publication Date Title
HK86090A (en) N-phenylmethylalkadienamide derivatives and compositions for use as analgesics
HK74990A (en) N-phenylmethyl-alkynamide derivatives and compositions for use as analgesics
HK58590A (en) N-phenylmethyl-alkanamide derivatives and compositions for use as analgesics
ES9000023A1 (es) Un procedimiento para preparar nuevos antibioticos macrociclicos que contienen anillos de dihidrobenzofurano y de pirano
JPS5681561A (en) Anilide derivative* its manufacture and its use
CA2108903A1 (en) Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
AU2418692A (en) New 3,5-di-tert.butyl-4-hydroxyphenyl derivatives, methods of preparing them and drugs containing them
EP0433679A3 (en) Pharmaceutical compositions for inhibition of maillard's reaction
MY100095A (en) 2-oxo-imidazolidine compounds, a process for preparing the same and a pharmaceutical composition.
DE3568440D1 (en) New (8s)-8-fluoroerythromycin derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them
EP0135189A3 (en) Pharmaceutically useful malonamides
CA2026278A1 (en) Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis Disorders
MY102706A (en) Compounds & compositions having anti- inflammatory and analgesic activity
DE3663660D1 (en) Û4.2.0¨bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same
KR880013896A (ko) 벤조푸로[3,2-c]퀴놀린 화합물
JPS54125663A (en) Carcinostatic agent and novel compound having carcinostatic activity
DE3662693D1 (en) 1-methyl-15-alpha-alkyl-androsta-1,4-diene-3,17-diones, process for their preparation and pharmaceutical compositions containing them
DE3175939D1 (en) Use of gamma-piperidino-butyrophenones for the preparation of medicaments for treating diarrhoea
IE44999L (en) Hydrazinopyridazine derivatives.
EP0322248A3 (en) Compounds effective against cerebral insufficiency
TW353071B (en) Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
IL91261A0 (en) Pharmaceutical compositions containing carbinolo-imidazoles
JPS57140721A (en) Antipyretic and analgesic agent containing o- or m-aminobenzoic acid derivative
JPS57126418A (en) Antiallergic agent
JPS5681579A (en) Prostacyclin derivative

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)