JPS5681579A - Prostacyclin derivative - Google Patents

Prostacyclin derivative

Info

Publication number
JPS5681579A
JPS5681579A JP15796279A JP15796279A JPS5681579A JP S5681579 A JPS5681579 A JP S5681579A JP 15796279 A JP15796279 A JP 15796279A JP 15796279 A JP15796279 A JP 15796279A JP S5681579 A JPS5681579 A JP S5681579A
Authority
JP
Japan
Prior art keywords
formula
compound
group
lower alkyl
titled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15796279A
Other languages
Japanese (ja)
Inventor
Takeshi Yu
Takeo Oba
Toshio Tanaka
Kenzo Watanabe
Kiyoshi Sakauchi
Seiji Kurozumi
Noriaki Okamura
Akira Otsu
Tatsuyuki Naritomo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP15796279A priority Critical patent/JPS5681579A/en
Publication of JPS5681579A publication Critical patent/JPS5681579A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I [R1 is H, lower alkyl or pharmaceutically acceptable salt; one or both of R2 and R3 are groups of formula II (R6 is aryl or alky; n is 0 or 1); when one of R2 and R3 is group of formula II, the other is H; the broken line is double bond with the solid line (Δ5 or Δ6); R4 is H or (protected) OH; R5 is H or group of formula III (R7 is H or protecting group of OH)].
EXAMPLE: Methyl 7-cyclopentyl-6,2'-epoxy-7-phenylthio-6-heptenoate.
USE: A medicine having an inhibitory action of platelet aggregation, hypotensive and smooth muscle relaxing actions. Stable to water and will not be easily hydrolyzed even by the acid treatment. Characterized by the high stability in the living body.
PROCESS: A compound of formula IV (R1 is lower alkyl) is reacted with a compound of the formula R6SX (X is Cl or Br) to give the titled substance of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP15796279A 1979-12-07 1979-12-07 Prostacyclin derivative Pending JPS5681579A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15796279A JPS5681579A (en) 1979-12-07 1979-12-07 Prostacyclin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15796279A JPS5681579A (en) 1979-12-07 1979-12-07 Prostacyclin derivative

Publications (1)

Publication Number Publication Date
JPS5681579A true JPS5681579A (en) 1981-07-03

Family

ID=15661249

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15796279A Pending JPS5681579A (en) 1979-12-07 1979-12-07 Prostacyclin derivative

Country Status (1)

Country Link
JP (1) JPS5681579A (en)

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