CA2026278A1 - Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis Disorders - Google Patents

Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis Disorders

Info

Publication number
CA2026278A1
CA2026278A1 CA2026278A CA2026278A CA2026278A1 CA 2026278 A1 CA2026278 A1 CA 2026278A1 CA 2026278 A CA2026278 A CA 2026278A CA 2026278 A CA2026278 A CA 2026278A CA 2026278 A1 CA2026278 A1 CA 2026278A1
Authority
CA
Canada
Prior art keywords
combatting
acid compounds
alkylphosphoric acid
alkylamino
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2026278A
Other languages
French (fr)
Other versions
CA2026278C (en
Inventor
Hansjorg Eibl
Clemens Unger
Jurgen Engel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6390272&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2026278(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2026278A1 publication Critical patent/CA2026278A1/en
Application granted granted Critical
Publication of CA2026278C publication Critical patent/CA2026278C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/664—Amides of phosphorus acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Abstract

The use of alkylphosphoric acid compounds of formula I

where in formula I R represents a saturated or unsaturated hydrocarbon radical with 12 to 24 carbon atoms or where R
represents the group -CH2-CHR3-CH2-Z-R4 and R3 is a C1-C6-alkoxy group or a C1-C6-alkoxymethyl group, Z represents oxygen or sulphur and R4 represents a C1-C24-alkyl radical, X is an oxygen atom, NH or NR2 and Y is an oxygen atom or NH, R1 is a C1-C8-alkyl group, or where R1 represents a C2-C8-alkyl group which is unsaturated and/or substituted by halogen, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, tri-C1-C6-alkylamino, hydroxy, carboxy, C3-C8-cycloalkyl or phenyl for the preparation of a medicament for combatting psoriasis disorders.
CA002026278A 1989-09-27 1990-09-26 Use of alkylphosphoric acid compounds for combatting psoriasis disorders Expired - Lifetime CA2026278C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3932183.5 1989-09-27
DE3932183 1989-09-27

Publications (2)

Publication Number Publication Date
CA2026278A1 true CA2026278A1 (en) 1991-03-28
CA2026278C CA2026278C (en) 1996-04-30

Family

ID=6390272

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002026278A Expired - Lifetime CA2026278C (en) 1989-09-27 1990-09-26 Use of alkylphosphoric acid compounds for combatting psoriasis disorders

Country Status (17)

Country Link
EP (2) EP0916343A1 (en)
JP (1) JP3176615B2 (en)
CA (1) CA2026278C (en)
DD (1) DD298052A5 (en)
DE (1) DE4029747C2 (en)
EG (1) EG19338A (en)
FI (1) FI904726A0 (en)
HU (1) HU209589B (en)
IE (1) IE903464A1 (en)
LT (1) LT3804B (en)
LV (1) LV10391B (en)
MC (1) MC2150A1 (en)
NO (1) NO904184L (en)
PT (1) PT95422B (en)
RU (1) RU1837877C (en)
UA (1) UA19335A (en)
ZA (1) ZA907702B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120115814A1 (en) * 2009-07-09 2012-05-10 Expergen Drug Development Gmbh Liquid Pharmaceutical Form Of Alkylphosphocholine And Method For Preparing Same

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4233044A1 (en) * 1992-10-01 1994-04-07 Asta Medica Ag Phospholipid derivatives that contain higher elements of the 5th main group
US5958906A (en) * 1992-10-01 1999-09-28 Asta-Medica Aktiengesellschaft Phospholipid derivatives containing higher elements of the fifth main group
DE4235911A1 (en) * 1992-10-23 1994-04-28 Asta Medica Ag Stabilized hexadecylphosphocholine solutions in glycerol alkyl ethers
CN100413492C (en) 1998-01-22 2008-08-27 赞塔里斯有限公司 Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis
DE102006004821B4 (en) * 2006-01-30 2020-12-10 Cuma Kilic Collection container for waste and building rubble

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761404A (en) * 1985-07-01 1988-08-02 Merck & Co., Inc. Phospholipid analogs useful as PAF synthesis inhibitors
CA1338627C (en) * 1985-12-04 1996-10-01 Hansjorg Eibl Pharmaceuticals based on phosphoric acid esters for use in tumor therapy, and process for their preparation
DE3829899C2 (en) * 1988-09-02 1994-12-15 Reutter Werner Glycerine glycophosphatides and pharmaceutical compositions containing them for combating skin diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120115814A1 (en) * 2009-07-09 2012-05-10 Expergen Drug Development Gmbh Liquid Pharmaceutical Form Of Alkylphosphocholine And Method For Preparing Same
US8722648B2 (en) * 2009-07-09 2014-05-13 Paul Meng Liquid pharmaceutical form of alkylphosphocholine and method for preparing same

Also Published As

Publication number Publication date
EP0916343A1 (en) 1999-05-19
LV10391A (en) 1995-02-20
PT95422B (en) 1997-07-31
EG19338A (en) 1994-12-30
PT95422A (en) 1991-05-22
LTIP1488A (en) 1995-06-26
EP0419998A3 (en) 1991-10-23
FI904726A0 (en) 1990-09-26
DE4029747A1 (en) 1991-04-11
NO904184L (en) 1991-04-02
LV10391B (en) 1995-10-20
MC2150A1 (en) 1992-03-10
UA19335A (en) 1997-12-25
JP3176615B2 (en) 2001-06-18
LT3804B (en) 1996-03-25
IE903464A1 (en) 1991-04-10
JPH03130228A (en) 1991-06-04
RU1837877C (en) 1993-08-30
EP0419998A2 (en) 1991-04-03
ZA907702B (en) 1991-07-31
DE4029747C2 (en) 2003-10-02
CA2026278C (en) 1996-04-30
NO904184D0 (en) 1990-09-26
HU209589B (en) 1994-08-29
HU906233D0 (en) 1991-03-28
DD298052A5 (en) 1992-02-06
HUT55992A (en) 1991-07-29

Similar Documents

Publication Publication Date Title
WO1987003478A3 (en) Medicaments
IE861820L (en) 2-hydroxy-2-phenylethylaminotetralines
ES2131207T3 (en) AMIDAS DERIVATIVES OF VALPROIC ACID AND 2-VALPROENOIC ACID AND ITS USE AS ANTICONVULSIVES.
AU557691B2 (en) 2-penem antibiotics and their oxa-aza-, and carba analogues
AU572497B2 (en) 1,2,3,4-tetrahydro-2-naphthylamines
ES2105108T3 (en) STEROIDS FOR THE TREATMENT OF PROSTATIC HYPERTROPHY, ITS PREPARATION AND ITS USE.
AU2246292A (en) Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
DE59209663D1 (en) Process for the manufacture of a medicament for oral or topical administration in the treatment of leishmaniasis
AU1302388A (en) Method of treating anxiety with tetrahydrobenz(c,d)indole-6- carboxamides
AU2868689A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
AU4732089A (en) Sulfur-containing heterocyclic compounds
CA2026278A1 (en) Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis Disorders
EP0270046A3 (en) Pharmaceutical composition for treatment of cataract
GEP19971011B (en) process for production of Compounds for Combatting Psoriasis Disorders
PH21295A (en) Octahydroindolizine compounds useful as analgesics
AU2224795A (en) Ameliorant or remedy for paraneoplastic syndrome
ES8301230A1 (en) Amidotetrazole compounds and processes for their preparation.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry