CA2026278A1 - Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis Disorders - Google Patents
Use of Alkylphosphoric Acid Compounds for Combatting Psoriasis DisordersInfo
- Publication number
- CA2026278A1 CA2026278A1 CA2026278A CA2026278A CA2026278A1 CA 2026278 A1 CA2026278 A1 CA 2026278A1 CA 2026278 A CA2026278 A CA 2026278A CA 2026278 A CA2026278 A CA 2026278A CA 2026278 A1 CA2026278 A1 CA 2026278A1
- Authority
- CA
- Canada
- Prior art keywords
- combatting
- acid compounds
- alkylphosphoric acid
- alkylamino
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The use of alkylphosphoric acid compounds of formula I
where in formula I R represents a saturated or unsaturated hydrocarbon radical with 12 to 24 carbon atoms or where R
represents the group -CH2-CHR3-CH2-Z-R4 and R3 is a C1-C6-alkoxy group or a C1-C6-alkoxymethyl group, Z represents oxygen or sulphur and R4 represents a C1-C24-alkyl radical, X is an oxygen atom, NH or NR2 and Y is an oxygen atom or NH, R1 is a C1-C8-alkyl group, or where R1 represents a C2-C8-alkyl group which is unsaturated and/or substituted by halogen, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, tri-C1-C6-alkylamino, hydroxy, carboxy, C3-C8-cycloalkyl or phenyl for the preparation of a medicament for combatting psoriasis disorders.
where in formula I R represents a saturated or unsaturated hydrocarbon radical with 12 to 24 carbon atoms or where R
represents the group -CH2-CHR3-CH2-Z-R4 and R3 is a C1-C6-alkoxy group or a C1-C6-alkoxymethyl group, Z represents oxygen or sulphur and R4 represents a C1-C24-alkyl radical, X is an oxygen atom, NH or NR2 and Y is an oxygen atom or NH, R1 is a C1-C8-alkyl group, or where R1 represents a C2-C8-alkyl group which is unsaturated and/or substituted by halogen, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, tri-C1-C6-alkylamino, hydroxy, carboxy, C3-C8-cycloalkyl or phenyl for the preparation of a medicament for combatting psoriasis disorders.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3932183 | 1989-09-27 | ||
| DEP3932183.5 | 1989-09-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2026278A1 true CA2026278A1 (en) | 1991-03-28 |
| CA2026278C CA2026278C (en) | 1996-04-30 |
Family
ID=6390272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002026278A Expired - Lifetime CA2026278C (en) | 1989-09-27 | 1990-09-26 | Use of alkylphosphoric acid compounds for combatting psoriasis disorders |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0419998A3 (en) |
| JP (1) | JP3176615B2 (en) |
| CA (1) | CA2026278C (en) |
| DD (1) | DD298052A5 (en) |
| DE (1) | DE4029747C2 (en) |
| EG (1) | EG19338A (en) |
| FI (1) | FI904726A7 (en) |
| HU (1) | HU209589B (en) |
| IE (1) | IE903464A1 (en) |
| LT (1) | LT3804B (en) |
| LV (1) | LV10391B (en) |
| MC (1) | MC2150A1 (en) |
| NO (1) | NO904184L (en) |
| PT (1) | PT95422B (en) |
| RU (1) | RU1837877C (en) |
| UA (1) | UA19335A (en) |
| ZA (1) | ZA907702B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120115814A1 (en) * | 2009-07-09 | 2012-05-10 | Expergen Drug Development Gmbh | Liquid Pharmaceutical Form Of Alkylphosphocholine And Method For Preparing Same |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4233044A1 (en) * | 1992-10-01 | 1994-04-07 | Asta Medica Ag | Phospholipid derivatives that contain higher elements of the 5th main group |
| US5958906A (en) * | 1992-10-01 | 1999-09-28 | Asta-Medica Aktiengesellschaft | Phospholipid derivatives containing higher elements of the fifth main group |
| DE4235911A1 (en) * | 1992-10-23 | 1994-04-28 | Asta Medica Ag | Stabilized hexadecylphosphocholine solutions in glycerol alkyl ethers |
| HUP0004363A3 (en) * | 1998-01-22 | 2002-12-28 | Zentaris Gmbh | Solid pharmaceutical compositions containing miltefosine for use in the treatment of leishmaniasis |
| RU2190390C2 (en) * | 1998-01-22 | 2002-10-10 | Центарис АГ | Solid pharmaceutical composition for oral administration in treatment of leishmaniasis and method of its production, pharmaceutical combination for treatment of leishmaniasis in mammals and method of treatment (versions) |
| RU2196583C1 (en) * | 2001-05-29 | 2003-01-20 | Барбинов Вячеслав Викторович | Agent for external therapy of psoriasis and method of its preparing |
| DE102006004821B4 (en) * | 2006-01-30 | 2020-12-10 | Cuma Kilic | Collection container for waste and building rubble |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761404A (en) * | 1985-07-01 | 1988-08-02 | Merck & Co., Inc. | Phospholipid analogs useful as PAF synthesis inhibitors |
| IE59777B1 (en) * | 1985-12-04 | 1994-04-06 | Max Planck Gesellschaft | Medicaments |
| DE3829899C2 (en) * | 1988-09-02 | 1994-12-15 | Reutter Werner | Glycerine glycophosphatides and pharmaceutical compositions containing them for combating skin diseases |
-
1990
- 1990-09-18 EP EP19900117888 patent/EP0419998A3/en not_active Ceased
- 1990-09-18 EP EP98112091A patent/EP0916343A1/en not_active Withdrawn
- 1990-09-20 DE DE4029747A patent/DE4029747C2/en not_active Expired - Lifetime
- 1990-09-25 EG EG56690A patent/EG19338A/en active
- 1990-09-25 MC MC902151A patent/MC2150A1/en unknown
- 1990-09-25 DD DD90344186A patent/DD298052A5/en not_active IP Right Cessation
- 1990-09-26 NO NO90904184A patent/NO904184L/en unknown
- 1990-09-26 RU SU904831261A patent/RU1837877C/en active
- 1990-09-26 HU HU906233A patent/HU209589B/en not_active IP Right Cessation
- 1990-09-26 UA UA4831261A patent/UA19335A/en unknown
- 1990-09-26 ZA ZA907702A patent/ZA907702B/en unknown
- 1990-09-26 PT PT95422A patent/PT95422B/en not_active IP Right Cessation
- 1990-09-26 IE IE346490A patent/IE903464A1/en unknown
- 1990-09-26 CA CA002026278A patent/CA2026278C/en not_active Expired - Lifetime
- 1990-09-26 FI FI904726A patent/FI904726A7/en not_active Application Discontinuation
- 1990-09-27 JP JP25549990A patent/JP3176615B2/en not_active Expired - Fee Related
-
1992
- 1992-10-27 LV LVP-92-169A patent/LV10391B/en unknown
-
1993
- 1993-11-25 LT LTIP1488A patent/LT3804B/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120115814A1 (en) * | 2009-07-09 | 2012-05-10 | Expergen Drug Development Gmbh | Liquid Pharmaceutical Form Of Alkylphosphocholine And Method For Preparing Same |
| US8722648B2 (en) * | 2009-07-09 | 2014-05-13 | Paul Meng | Liquid pharmaceutical form of alkylphosphocholine and method for preparing same |
Also Published As
| Publication number | Publication date |
|---|---|
| NO904184D0 (en) | 1990-09-26 |
| RU1837877C (en) | 1993-08-30 |
| HU906233D0 (en) | 1991-03-28 |
| FI904726A0 (en) | 1990-09-26 |
| PT95422B (en) | 1997-07-31 |
| LTIP1488A (en) | 1995-06-26 |
| JPH03130228A (en) | 1991-06-04 |
| FI904726A7 (en) | 1991-03-28 |
| DE4029747C2 (en) | 2003-10-02 |
| CA2026278C (en) | 1996-04-30 |
| HUT55992A (en) | 1991-07-29 |
| ZA907702B (en) | 1991-07-31 |
| HU209589B (en) | 1994-08-29 |
| EG19338A (en) | 1994-12-30 |
| LV10391A (en) | 1995-02-20 |
| EP0916343A1 (en) | 1999-05-19 |
| DD298052A5 (en) | 1992-02-06 |
| IE903464A1 (en) | 1991-04-10 |
| NO904184L (en) | 1991-04-02 |
| JP3176615B2 (en) | 2001-06-18 |
| UA19335A (en) | 1997-12-25 |
| DE4029747A1 (en) | 1991-04-11 |
| MC2150A1 (en) | 1992-03-10 |
| PT95422A (en) | 1991-05-22 |
| EP0419998A3 (en) | 1991-10-23 |
| EP0419998A2 (en) | 1991-04-03 |
| LV10391B (en) | 1995-10-20 |
| LT3804B (en) | 1996-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |