HK70090A - A new process for the preparation of alpha-6-deoxy-tetracyclines - Google Patents

A new process for the preparation of alpha-6-deoxy-tetracyclines

Info

Publication number
HK70090A
HK70090A HK700/90A HK70090A HK70090A HK 70090 A HK70090 A HK 70090A HK 700/90 A HK700/90 A HK 700/90A HK 70090 A HK70090 A HK 70090A HK 70090 A HK70090 A HK 70090A
Authority
HK
Hong Kong
Prior art keywords
tetracyclines
deoxy
alpha
preparation
new process
Prior art date
Application number
HK700/90A
Other languages
English (en)
Inventor
Philip Ronald Page
Original Assignee
Hovione Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT77210A external-priority patent/PT77210A/pt
Priority claimed from PT7833484A external-priority patent/PT78334A/pt
Application filed by Hovione Int Ltd filed Critical Hovione Int Ltd
Publication of HK70090A publication Critical patent/HK70090A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
HK700/90A 1983-08-17 1990-09-06 A new process for the preparation of alpha-6-deoxy-tetracyclines HK70090A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT77210A PT77210A (fr) 1983-08-17 1983-08-17 Nouveau procede pour preparation de alpha-6-deoxy-tetracyclines
PT7833484A PT78334A (en) 1984-03-29 1984-03-29 Preparation of the alpha-6-deoxy-tetracyclines new process

Publications (1)

Publication Number Publication Date
HK70090A true HK70090A (en) 1990-09-14

Family

ID=26653438

Family Applications (1)

Application Number Title Priority Date Filing Date
HK700/90A HK70090A (en) 1983-08-17 1990-09-06 A new process for the preparation of alpha-6-deoxy-tetracyclines

Country Status (11)

Country Link
US (1) US4597904A (da)
EP (1) EP0137661B1 (da)
KR (1) KR870001142B1 (da)
AU (1) AU548771B2 (da)
CA (1) CA1242704A (da)
DE (1) DE3480339D1 (da)
DK (1) DK386784A (da)
ES (1) ES8600734A1 (da)
FR (1) FR2550788B1 (da)
HK (1) HK70090A (da)
NZ (1) NZ209262A (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
HU198173B (en) * 1987-09-18 1989-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing doxycycline
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
WO1990007492A1 (en) * 1989-01-04 1990-07-12 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
NZ544826A (en) * 2003-07-25 2008-07-31 Warner Chilcott Co Inc A doxycycline metal complex in a solid dosage form
AU2005244988C1 (en) 2004-05-21 2012-06-28 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
MX2007008724A (es) * 2005-01-21 2007-09-21 Warner Chilcott Co Inc Complejo metalico de tetraciclina en una forma de dosificacion solida.
AU2007235279B2 (en) * 2006-04-07 2012-12-06 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
EP2076133B1 (en) * 2006-10-11 2012-12-12 President and Fellows of Harvard College Synthesis of enone intermediate
EP2424834B1 (en) 2009-04-30 2018-07-11 President and Fellows of Harvard College Synthesis of tetracyclines and intermediates thereof
CN110023505B (zh) * 2016-10-27 2023-04-04 瓦纳迪斯诊断公司 用于处理滚环扩增产物的方法
CN107098825B (zh) * 2017-04-10 2019-05-31 广东中农联生物制药有限公司 一种强力霉素的高效制备方法
CN107056641B (zh) * 2017-04-10 2019-05-17 河南师范大学 一种强力霉素的制备方法
CN113248397B (zh) * 2021-07-01 2021-11-05 山东国邦药业有限公司 一种盐酸多西环素的制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA668581A (en) * 1963-08-13 R. D. Mccormick Jerry Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (da) * 1960-05-23 1966-05-25
US3484483A (en) * 1966-10-31 1969-12-16 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US3397231A (en) * 1967-04-12 1968-08-13 Pfizer & Co C Refining of alpha-6-deoxy-5-oxytetracycline
US3442943A (en) * 1967-08-16 1969-05-06 American Cyanamid Co Process for preparing 6-deoxytetracyclines
AU2940371A (en) * 1970-06-12 1972-11-30 Societa Farmaceutici Italia 6-deoxy-5-oxytetracycline-5-esters
CA942743A (en) * 1970-07-03 1974-02-26 Ivan Villax Process for producing 6-methylenetetracyclines and 6-deoxytetracyclines
US4061676A (en) * 1970-07-03 1977-12-06 Ivan Villax Recovery of doxycycline and products thereof
US3795707A (en) * 1970-12-28 1974-03-05 Rachelle Labor Italia Spa Manufacture of alpha-6-deoxytetracyclines
US4207258A (en) * 1972-02-24 1980-06-10 Ankerfarm S.P.A. Process for the preparatin of α-6-deoxytetracyclines
SE435619C (sv) * 1973-02-01 1985-10-31 Pfizer Forfarande for framstellning av en 6alfa-deoxitetracyklin
US3954862A (en) * 1973-04-20 1976-05-04 Pfizer Inc. Process for producing α-6-deoxytetracyclines
HU167250B (da) * 1973-06-08 1975-09-27
GB1459861A (en) * 1973-06-21 1976-12-31 Pfizer Process for 11a-dehalogenation of 11a-halotetracyclines
DK501574A (da) * 1973-09-28 1975-05-26 Ankerfarm Spa
US3907890A (en) * 1974-05-28 1975-09-23 Pfizer Preparation of alpha-6-deoxy-5-hydroxytetracycline
AR208347A1 (es) * 1974-12-19 1976-12-20 Pfizer Mejora en la produccion de alfa-6-deoxitetraciclinas
US4001321A (en) * 1975-06-26 1977-01-04 Pfizer Inc. Preparation of α-6-deoxytetracyclines
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
GB1593927A (en) * 1978-05-15 1981-07-22 Pliva Pharm & Chem Works T-butyl derivatives of 5-hydroxy-tetracycline and a process for preparing the same
IT1198342B (it) * 1980-07-10 1988-12-21 Carbo Biochimica Srl Processo per la produzione di alfa-6-desossi-tetracicline
DE3131954C2 (de) * 1981-08-13 1984-10-31 Degussa Ag, 6000 Frankfurt Metallkomplexe von polymeren, gegebenenfalls vernetzten Organosiloxanaminen, Verfahren zu ihrer Herstellung und Verwendung
US4550096A (en) * 1982-01-19 1985-10-29 Plurichemie Anstalt Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same

Also Published As

Publication number Publication date
EP0137661A2 (en) 1985-04-17
FR2550788A1 (fr) 1985-02-22
KR870001142B1 (ko) 1987-06-11
FR2550788B1 (fr) 1989-11-17
AU548771B2 (en) 1986-01-02
NZ209262A (en) 1987-07-31
CA1242704A (en) 1988-10-04
EP0137661A3 (en) 1987-08-19
KR850001897A (ko) 1985-04-10
US4597904A (en) 1986-07-01
ES535223A0 (es) 1985-11-01
DK386784D0 (da) 1984-08-10
AU3197984A (en) 1985-02-21
EP0137661B1 (en) 1989-11-02
DE3480339D1 (en) 1989-12-07
ES8600734A1 (es) 1985-11-01
DK386784A (da) 1985-02-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)