HK22797A - Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same - Google Patents

Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same

Info

Publication number
HK22797A
HK22797A HK22797A HK22797A HK22797A HK 22797 A HK22797 A HK 22797A HK 22797 A HK22797 A HK 22797A HK 22797 A HK22797 A HK 22797A HK 22797 A HK22797 A HK 22797A
Authority
HK
Hong Kong
Prior art keywords
methods
pharmaceutical compositions
same
therapeutic treatment
preparation pharmaceutical
Prior art date
Application number
HK22797A
Other languages
English (en)
Inventor
Peter W Schiller
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of HK22797A publication Critical patent/HK22797A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK22797A 1988-06-30 1997-02-27 Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same HK22797A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA570874 1988-06-30

Publications (1)

Publication Number Publication Date
HK22797A true HK22797A (en) 1997-02-27

Family

ID=4138301

Family Applications (1)

Application Number Title Priority Date Filing Date
HK22797A HK22797A (en) 1988-06-30 1997-02-27 Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same

Country Status (8)

Country Link
US (1) US5312899A (el)
EP (1) EP0350221B1 (el)
AT (1) ATE136905T1 (el)
DE (1) DE68926269T2 (el)
ES (1) ES2085865T3 (el)
GR (1) GR3020139T3 (el)
HK (1) HK22797A (el)
SG (1) SG64368A1 (el)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602100A (en) * 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
JPH09505555A (ja) 1993-08-13 1997-06-03 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ,アズ リプレゼンテッド バイ ザ セクレタリー,デパートメント オブ ヘルス アンド ヒューマン サービシーズ TGF−βの活性を刺激および阻害する方法および組成物
SE9503924D0 (sv) * 1995-08-18 1995-11-07 Astra Ab Novel opioid peptides
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5885958A (en) * 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
SE9900961D0 (sv) * 1999-03-16 1999-03-16 Astra Ab Novel compounds
DE60143945D1 (de) * 2000-07-18 2011-03-10 Cornell Res Foundation Inc Medizinische verwendung von agonisten des mu-opioid rezeptors
US7316819B2 (en) 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
US7401046B2 (en) * 2001-07-25 2008-07-15 Chicago Board Options Exchange System and method for displaying option market information
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
HUE027110T2 (en) * 2003-02-04 2016-08-29 Cornell Res Foundation Inc Use of an aromatic cationic peptide
CN104383542B (zh) 2003-04-08 2017-09-26 普罗热尼奇制药公司 包含甲基纳曲酮的药物配方
CN100506841C (zh) * 2003-05-01 2009-07-01 科内尔研究基金会 将分子递送到细胞的方法和载体复合物
US20050215476A1 (en) * 2004-01-21 2005-09-29 Unigene Laboratories Inc. Amidated parathyroid hormone fragments and uses thereof
RU2376028C2 (ru) 2004-01-23 2009-12-20 Корнелл Рисеч Фаундейшн, Инк. Способ уменьшения окислительного повреждения (варианты)
US20050282756A1 (en) 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
EP1931369B1 (en) 2005-09-16 2016-08-17 Cornell Research Foundation, Inc. Aromatic-cationic peptide for use in a method for reducing CD36 expression
US20100279944A1 (en) * 2006-03-30 2010-11-04 Ronald Mathison Suppression and treatment of neuropathic pain
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
PA8774201A1 (es) 2007-03-29 2009-06-23 Progenics Pharm Inc Antagonista del receptor
SI2139890T1 (sl) * 2007-03-29 2014-12-31 Wyeth Llc Antagonisti perifernih opioidnih receptorjev in njih uporaba
MX351611B (es) 2007-03-29 2017-10-20 Wyeth Llc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
EP2730578A1 (en) 2008-02-06 2014-05-14 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnal trexone
EP2712620A1 (en) 2008-02-07 2014-04-02 Cornell University Methods for Preventing or Treating Insulin Resistance
EP2262520B1 (en) 2008-02-26 2017-05-03 Cornell University Compositions for prevention and treatment of renal injury
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US20100331265A1 (en) 2009-03-20 2010-12-30 Tompkins Ronald G Methods for the prevention and treatment of burn injuries and secondary complications
EP3251686A1 (en) * 2009-08-12 2017-12-06 Cornell University Methods for preventing or treating metabolic syndrome
US8470784B2 (en) 2009-08-24 2013-06-25 Stealth Peptides International, Inc. Methods and compositions for preventing or treating ophthalmic conditions
JP2013506696A (ja) 2009-10-05 2013-02-28 コーネル ユニヴァーシティー 心不全の予防又は処置の方法
CA2850520C (en) 2011-09-29 2021-08-31 Mayo Foundation For Medical Education And Research Aromatic-cationic peptides and methods for using same
WO2017156403A1 (en) * 2016-03-11 2017-09-14 Stealth Biotherapeutics Crystalline salt forms
WO2018187400A1 (en) 2017-04-05 2018-10-11 Stealth Biotherapeutics Corp. Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2
WO2019051494A1 (en) 2017-09-11 2019-03-14 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND USES THEREOF
PL439243A1 (pl) * 2021-10-18 2023-04-24 Instytut Medycyny Doświadczalnej I Klinicznej Im. Mirosława Mossakowskiego Polskiej Akademii Nauk Nowy analog dermorfiny jako lek przeciwbólowy do stosowania w leczeniu bólu przewlekłego

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
DE3435727A1 (de) * 1984-09-28 1986-04-10 Victor Dipl.-Chem. Dr.med. 6200 Wiesbaden Brantl Pharmakologisch aktive peptide

Also Published As

Publication number Publication date
EP0350221A2 (en) 1990-01-10
US5312899A (en) 1994-05-17
SG64368A1 (en) 1999-04-27
GR3020139T3 (en) 1996-08-31
ES2085865T3 (es) 1996-06-16
DE68926269D1 (de) 1996-05-23
EP0350221B1 (en) 1996-04-17
ATE136905T1 (de) 1996-05-15
DE68926269T2 (de) 1996-08-14
EP0350221A3 (en) 1990-09-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)